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Effects of Vitex trifolia L. leaf extracts and phytoconstituents on cytokine production in human U937 macrophages

Hai-Ning Wee, Soek-Ying Neo, Deepika Singh, Hui-Chuing Yew et al. • BMC Complementary Medicine and Therapies (2020)

Abstract Background Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growing in co...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12906-020-02884-w

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

Katya Carbone, Fabio Gervasi, Latipa Kozhamzharova, Nazgul Altybaeva et al. • Frontiers in Molecular Biosciences (2023)

Plants, with their range of pharmacologically active molecules, represent the most promising source for the production of new anticancer drugs and for the formulation of adjuvants in chemotherapy treatments to reduce drug content and/or cou...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmolb.2023.1157558