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Showing 18 of 18 academic articles

ROS/Enzyme Dual-Responsive Drug Delivery System for Targeted Colorectal Cancer Therapy: Synergistic Chemotherapy, Anti-Inflammatory, and Gut Microbiota Modulation

Xin Zhang, Ruonan Lian, Bingbing Fan, Lei Meng et al. • Pharmaceutics (2025)

Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related mortality, driven by chronic inflammation, gut microbiota dysbiosis, and complex tumor microenvironment interactions. Current therapies are limited by systemic toxicit...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics17070940

Guidelines for information about therapy experiments: a proposal on best practice for recording experimental data on cancer therapy

González-Beltrán Alejandra N, Yong May Y, Dancey Gairin, Begent Richard • BMC Research Notes (2012)

Abstract Background Biology, biomedicine and healthcare have become data-driven enterprises, where scientists and clinicians need to generate, access, validate, interpret and integrate different kinds of experimental and patient-related dat...

DOAJ Open Access (DOAJ) DOI: 10.1186/1756-0500-5-10

Nanotechnology and its Applications in Medicine

Anna Pratima Nikalje • Medicinal Chemistry (2015)

Nanotechnologyis the study of extremely small structures, having size of 0.1 to 100 nm. Nano medicine is a relatively new field of science and technology. Brief explanation of various types of pharmaceutical nano systems is given. Classific...

OPENALEX DOI: https://doi.org/10.4172/2161-0444.1000247

A recent update on development, synthesis methods, properties and application of natural products derived carbon dots

Soumitra Sahana, Anupam Gautam, Rajveer Singh, Shivani Chandel • Natural Products and Bioprospecting (2023)

Abstract Natural resources are practically infinitely abundant in nature, which stimulates scientists to create new materials with inventive uses and minimal environmental impact. Due to the various benefits of natural carbon dots (NCDs) fr...

DOAJ Open Access (DOAJ) DOI: 10.1007/s13659-023-00415-x

USP1-trapping lesions as a source of DNA replication stress and genomic instability

Kate E. Coleman, Yandong Yin, Sarah Kit Leng Lui, Sarah Keegan et al. • Nature Communications (2022)

Here the authors provide mechanistic insights into how auto-cleavage of the USP1 deubiquitinase regulates DNA replication and genome stability. Implications for the targeting of USP1 activity via protein-DNA trapping in cancer therapy are d...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-022-29369-3

Development of Anticancer Peptides Using Artificial Intelligence and Combinational Therapy for Cancer Therapeutics

Ji Su Hwang, Seok Gi Kim, Tae Hwan Shin, Yong Eun Jang et al. • Pharmaceutics (2022)

Cancer is a group of diseases causing abnormal cell growth, altering the genome, and invading or spreading to other parts of the body. Among therapeutic peptide drugs, anticancer peptides (ACPs) have been considered to target and kill cance...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics14050997

Machine Learning in Healthcare Communication

Sarkar Siddique, James C. L. Chow • Encyclopedia (2021)

Machine learning (ML) is a study of computer algorithms for automation through experience. ML is a subset of artificial intelligence (AI) that develops computer systems, which are able to perform tasks generally having need of human intelli...

OPENALEX cc-by DOI: https://doi.org/10.3390/encyclopedia1010021