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Constraining PERMANOVA and LDM to within-set comparisons by projection improves the efficiency of analyses of matched sets of microbiome data

Zhengyi Zhu, Glen A. Satten, Caroline Mitchell, Yi-Juan Hu • Microbiome (2021)

Abstract Background Matched-set data arise frequently in microbiome studies. For example, we may collect pre- and post-treatment samples from a set of individuals, or use important confounding variables to match data from case participants ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40168-021-01034-9