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Showing 5 of 5 academic articles

Publisher Correction: A general and flexible method for signal extraction from single-cell RNA-seq data

Davide Risso, Fanny Perraudeau, Svetlana Gribkova, Sandrine Dudoit et al. • Nature Communications (2019)

The original PDF version of this Article contained errors in two equations. In Eq. (1), all Γ symbols were inadvertently omitted. In the second equation in the subsection entitled ‘1. Dispersion optimization’ within the Methods section ‘ZIN...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-019-08614-2

Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

Xinbo Wang, Jiaying Miao, Sizhen Wang, Rongxi Shen et al. • Molecular Cancer (2022)

Abstract Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical features. Me...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-022-01596-8

The Advances of Single-Cell RNA-Seq in Kidney Immunology

Honghui Zeng, Honghui Zeng, Xiaoqiang Yang, Xiaoqiang Yang et al. • Frontiers in Physiology (2021)

Kidney diseases are highly prevalent and treatment is costly. Immune cells play important roles in kidney diseases; however, it has been challenging to investigate the contribution of each cell type in kidney pathophysiology. Recently, the ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2021.752679

Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease

Clara Muñoz-Castro, Ayush Noori, Colin G. Magdamo, Zhaozhi Li et al. • Journal of Neuroinflammation (2022)

Abstract Background Astrocytes and microglia react to Aβ plaques, neurofibrillary tangles, and neurodegeneration in the Alzheimer’s disease (AD) brain. Single-nuclei and single-cell RNA-seq have revealed multiple states or subpopulations of...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12974-022-02383-4