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Diagnostic innovations in Equine Parasitology: a Nanogold-ELISA for sensitive serodiagnosis of migratory strongylus vulgaris larvae infections

Hanadi B. A. Baghdadi, Mohamed Abdelsalam, Marwa M. Attia • BMC Veterinary Research (2024)

Abstract Strongylus vulgaris, a devastating parasitic nematode in equids, causes life-threatening verminous aneurysms that are challenging to diagnose early. This study pioneered integrating nanotechnology into an indirect enzyme-linked imm...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12917-024-04389-x

Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing

Ali Aytac Seymen, Ezgi Gulten, Erol Ozgur, Bülend Ortaç et al. • Scientific Reports (2023)

Abstract Coronavirus Disease-19 (COVID-19) is a highly contagious infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The development of rapid antigen tests has contributed to easing the burden on ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-31177-8

Evaluation of Blood-Based Antibody Rapid Testing for HIV Early Therapy: A Meta-Analysis of the Evidence

Xiaojie Huang, Xinchao Liu, Jieqing Chen, Yugang Bao et al. • Frontiers in Immunology (2018)

BackgroundWestern blot (WB) assay is considered the gold standard test for HIV infection confirmation. However, it requires technical expertise and is quite time-consuming. WHO recommends blood-based rapid diagnosis to achieve same-day test...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2018.01458

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Vladimir Tesar, Conor Judge, John Kelleher, Zdenka Hrušková et al. • RMD Open (2024)

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS>0) is often missing or inaccurate in re...

DOAJ Open Access (DOAJ) DOI: 10.1136/rmdopen-2023-003962

The Colorectal Cancer Screening Programme in the Basque Country: obtaining a good performance by means of professional collaboration

Isabel Portillo, Isabel Idigoras, Isabel Bilbao, Jose Luis Hurtado et al. • International Journal of Integrated Care (2019)

Introduction: The Basque Health Service approved the Colorectal Cancer (CRC) screening programme in 2008; targeted at residents (50 to 69 years old) estimated 598,201 by biennial faecal immunochemical test (FIT) and colonoscopy in positive ...

DOAJ Open Access (DOAJ) DOI: 10.5334/ijic.s3166

‘Optimal’ cutoff selection in studies of depression screening tool accuracy using the PHQ‐9, EPDS, or HADS‐D: A meta‐research study

Eliana Brehaut, Dipika Neupane, Brooke Levis, Yin Wu et al. • International Journal of Methods in Psychiatric Research (2023)

Abstract Objectives Optimal cutoff thresholds are selected to separate ‘positive’ from ‘negative’ screening results. We evaluated how depression screening tool studies select optimal cutoffs. Methods We included studies from previously cond...

DOAJ Open Access (DOAJ) DOI: 10.1002/mpr.1956

Photoluminescent Nanomaterials for Medical Biotechnology

Evgenii L. Guryev, Samah Shanwar, Andrei V. Zvyagin, Sergey Mikhailovich Deyev et al. • Acta Naturae (2021)

Creation of various photoluminescent nanomaterials has significantly expanded the arsenal of approaches used in modern biomedicine. Their unique photophysical properties can significantly improve the sensitivity and specificity of diagnosti...

OPENALEX cc-by DOI: https://doi.org/10.32607/actanaturae.11180 PMC: 8327149

Clustered Regularly Interspaced Short Palindromic Repeat/Cas12a Mediated Multiplexable and Portable Detection Platform for GII Genotype Porcine Epidemic Diarrhoea Virus Rapid Diagnosis

Bingxu Qian, Bingxu Qian, Kai Liao, Dexin Zeng et al. • Frontiers in Microbiology (2022)

Porcine epidemic diarrhoea virus (PEDV) is a member of the genus Alphacoronavirus in the family Coronaviridae. It causes acute watery diarrhoea and vomiting in piglets with high a mortality rate. Currently, the GII genotype, PEDV, possesses...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2022.920801

The Utilization of Point of Care Ultrasound (POCUS) for the Confirmation of Gastric and Post-Pyloric Feeding Tube Placement in a Pediatric Intensive Care Unit

Alonso Marron, Michael Wolf, Marla Levine, Jeremy Boyd et al. • POCUS Journal (2025)

The aim of this study was to investigate the role of point of care ultrasound (POCUS) as an alternative imaging modality to confirm the location of gastric and post-pyloric feeding tubes in patients admitted to the pediatric intensive care ...

DOAJ Open Access (DOAJ) DOI: 10.24908/pocusj.v10i01.17785

Estimates for Lyme borreliosis infections based on models using sentinel canine and human seroprevalence data

Michael J. Cook, Basant K. Puri • Infectious Disease Modelling (2020)

Two models were developed to estimate Lyme borreliosis (LB) cases. One was based on the seroprevalence of Borrelia infections in human samples. This model used corrections for false negative and false positive results from published test se...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.idm.2020.10.004

Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: a Prospective Pilot Study

Agnese Ozolina, Agnese Ozolina, Marina Sarkele, Marina Sarkele et al. • Frontiers in Medicine (2016)

Introduction: Coagulation and fibrinolysis remain sparsely addressed with regards to acute respiratory distress syndrome (ARDS). We hypothesized that ARDS development might be associated with changes in plasma coagulation and fibrinolysis. ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2016.00064

Unlocking Clinical Data from Narrative Reports: A Study of Natural Language Processing

George M. Hripcsak, Carol Friedman, Philip O. Alderson, William DuMouchel et al. • Annals of Internal Medicine (1995)

OBJECTIVE: To evaluate the automated detection of clinical conditions described in narrative reports. DESIGN: Automated methods and human experts detected the presence or absence of six clinical conditions in 200 admission chest radiograph ...

OPENALEX DOI: https://doi.org/10.7326/0003-4819-122-9-199505010-00007

Integrating NLP to Enhance Algorithmic Identification of Metastatic and Castration‐Resistant Prostate Cancer in Large Claims‐Based Studies

Shannon R. Stock, Joshua A. Parrish, Michael T. Burns, Jessica L. Janes et al. • Cancer Medicine (2025)

ABSTRACT Purpose Accurate classification of prostate cancer (PC) disease states defined by the presence or absence of metastasis and castration resistance (CRPC) is critical but challenging in population‐based research. As chart review is n...

DOAJ Open Access (DOAJ) DOI: 10.1002/cam4.71406

Brain tumor grading based on Neural Networks and Convolutional Neural Networks

Yuehao Pan, Weimin Huang, Zhiping Lin, Wanzheng Zhu et al. • Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2015)

This paper studies brain tumor grading using multiphase MRI images and compares the results with various configurations of deep learning structure and baseline Neural Networks. The MRI images are used directly into the learning machine, wit...

OPENALEX DOI: https://doi.org/10.1109/embc.2015.7318458

Evaluating artificial intelligence for a focal nodular hyperplasia diagnosis using magnetic resonance imaging: preliminary findings

Mecit Kantarcı, Volkan Kızılgöz, Ramazan Terzi, Ahmet Enes Kılıç et al. • Diagnostic and Interventional Radiology (2025)

PURPOSE: This study aimed to evaluate the effectiveness of artificial intelligence (AI) in diagnosing focal nodular hyperplasia (FNH) of the liver using magnetic resonance imaging (MRI) and compare its performance with that of radiologists....

DOAJ Open Access (DOAJ) DOI: 10.4274/dir.2025.243095

Deep-learning–based non-contrast CT for detecting acute ischemic stroke: a systematic review and HSROC meta-analysis of patient-level diagnostic accuracy

Kalab Yigermal Gete, Asnakew Achaw Ayele • BMC Neurology (2025)

Abstract Background Non-contrast CT (NCCT) is first-line imaging for suspected acute ischemic stroke (AIS) but has limited early sensitivity; deep learning (DL) may improve patient-level detection. Objectives To estimate the diagnostic accu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12883-025-04528-3

Automated cell type annotation and exploration of single-cell signaling dynamics using mass cytometry

Dimitrios Kleftogiannnis, Sonia Gavasso, Benedicte Sjo Tislevoll, Nisha van der Meer et al. • iScience (2024)

Summary: Mass cytometry by time-of-flight (CyTOF) is an emerging technology allowing for in-depth characterization of cellular heterogeneity in cancer and other diseases. Unfortunately, high-dimensional analyses of CyTOF data remain quite d...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.isci.2024.110261

Machine learning in pain research

Jörn Lötsch, Alfred Ultsch • Pain (2017)

1. Introduction Pain and pain chronification are incompletely understood and unresolved medical problems that continue to have a high prevalence.14 It has been accepted that pain is a complex phenomenon.2,32,72 Contemporary methods of compu...

OPENALEX cc-by-nc-nd DOI: https://doi.org/10.1097/j.pain.0000000000001118 PMC: 5895117

Integrated Bioinformatics Analysis and Experimental Verification of Immune Cell Infiltration and the Related Core Genes in Ulcerative Colitis

Zhao D, Qin D, Yin L, Yang Q • Pharmacogenomics and Personalized Medicine (2023)

Danya Zhao,1 Danping Qin,2 Liming Yin,3 Qiang Yang4 1The First School of Clinical Medicine of Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Gastroenterology, The First Affiliated Hospital of Zheji...

DOAJ Open Access (DOAJ)