Academic Articles & Research Papers

Persistent sarcopenia after flare remission in experimental RA responds to dipyridamole and is associated with restoration of adenosine and A2BR signaling.

Sarcopenia in type 2 diabetes mellitus: from muscle quantity to multidimensional muscle health.

Sepsis-associated sarcopenia: Emerging insights into mechanisms and therapeutic approaches.

Bioactive isoprenylflavonoids contribute to the dual protective effects of Xianling Gubao against sarcopenia and osteoarthritis in SAMP8 mice.

Gut microbiome-metabolome signatures of osteosarcopenia in fracture patients in China.

GLP-1-Based Pharmacotherapies and Skeletal Muscle Health in Obesity: A Narrative Review of Body Composition, Muscle Function, and Sarcopenia-Related Outcomes.

Cohort profile: the Taiwan Initiative for Geriatric Epidemiological Research - a prospective cohort study on cognition

The Taiwan Initiative for Geriatric Epidemiological Research (TIGER) was founded in 2011 to elucidate the interrelationships among various predictors of global and domain-specific cognitive impairment, with the aim of identifying older adul...

Expert Consensus on Diagnosis and Management of Secondary Sarcopenia in Adults in Colombia: A Modified Delphi Study

ABSTRACT Background Secondary sarcopenia driven by chronic disease, acute illness, immobilization, malnutrition or treatment‐related factors contributes to functional decline, falls, disability, readmission and mortality. In Colombia, uneve...

Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice

Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...

Predictivity of bioimpedance phase angle for incident disability in older adults

Abstract Background Bioelectrical impedance analysis (BIA)‐derived phase angle is expected to be an efficient prognostic marker of health adverse events with aging as an alternative of muscle mass. We aimed to examine the predictive ability...

The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy

Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condit...

Association of triglyceride glucose-body roundness index and body roundness index with incident sarcopenia among Chinese older adults: A nationwide cohort study

Background: The relationship between TyG-BRI, BRI, and the sarcopenia definition proposed by the Asian Working Group for Sarcopenia (AWGS) in 2019 remains unclear. This research focused on exploring the relationship between the TyG-BRI inde...

Epidemiology and burden of osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease involving the cartilage and many of its surrounding tissues. Disease progression is usually slow but can ultimately lead to joint failure with pain and disability. OA of the hi...

S100A9 Mediates Neuroblastoma-Associated Skeletal Muscle Atrophy via O-GlcNAcylation Repression and Activate Mitophagy Activation.

Mitochondrial Transplantation Preserves Regenerative Capacity of Denervated Skeletal Muscle by Disrupting a Ca(2+) Overload-Mitophagy-Ferroptosis Circuit.

Improving Muscle Function Through a Multimodal Behavioural Intervention for Knee Osteoarthritis and Obesity: The POMELO Trial

ABSTRACT Background Treatments aimed at improving physical function and body composition, including reducing fat mass (FM) and increasing muscle mass, may benefit individuals with advanced knee osteoarthritis (OA) and obesity. We investigat...

Segmentation of muscle tissue in computed tomography images at the level of the L3 vertebra

With the increasing routine workload on radiologists associated with the need to analyze large numbers of images, there is a need to automate part of the analysis process. Sarcopenia is a condition in which there is a loss of muscle mass. T...

Diagnostic utility of body fat distribution parameters in distinguishing osteosarcopenia from osteoporosis or sarcopenia alone in postmenopausal women: a retrospective cross-sectional study.

Association between myosteatosis and impaired glucose metabolism: A deep learning whole‐body magnetic resonance imaging population phenotyping approach

Abstract Background There is increasing evidence that myosteatosis, which is currently not assessed in clinical routine, plays an important role in risk estimation in individuals with impaired glucose metabolism, as it is associated with th...