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Monogenic obesity due to MC4R deficiency: lessons from a multigenerational case

Eleni Z. Giannopoulou, Stefanie Zorn, Melanie Schirmer, Stephanie Brandt-Heunemann et al. • Molecular and Cellular Pediatrics (2026)

Abstract Background Melanocortin 4 receptor (MC4R) deficiency is the most common monogenic cause of obesity, yet remains underdiagnosed. Patients with monogenic obesity often undergo a frustrating diagnostic and therapeutic odyssey of years...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40348-025-00214-z

The Alberta Congenital Anomalies Surveillance System: a 40-year review with prevalence and trends for selected congenital anomalies, 1997–2019

R. Brian Lowry, Tanya Bedard, Xin Grevers, Susan Crawford et al. • Health Promotion and Chronic Disease Prevention in Canada (2023)

IntroductionCurrent published long-term provincial or territorial congenital anomaly data are lacking for Canada. We report on prevalence (per 1000 total births) and trends in 1997–2019, in Alberta, Canada, for selected congenital anomalies...

DOAJ Open Access (DOAJ) DOI: 10.24095/hpcdp.43.1.04

Innovative partnerships to advance public health training in community-based academic residency programs

Lo JC, Baudendistel TE, Dandekar A, Le PV et al. • Advances in Medical Education and Practice (2017)

Joan C Lo,1–3 Thomas E Baudendistel,2,3 Abhay Dandekar,3,4 Phuoc V Le,5 Stanton Siu,2,3 Bruce Blumberg6 1Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA; 2Department of Medicine, ...

DOAJ Open Access (DOAJ)

Effect of the mHealth-supported Healthy Future programme delivered by community health workers on maternal and child health in rural China: study protocol for a cluster randomised controlled trial

Huan Zhou, Sean Sylvia, Scott Rozelle, Gary L Darmstadt et al. • BMJ Open (2023)

Introduction Millions of young rural children in China still suffer from poor health and malnutrition, partly due to a lack of knowledge about optimal perinatal and child care among rural mothers and caregivers. Meanwhile, there is an urgen...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2022-065403

Familiar but neglected: identification of gaps and recommendations to close them on exclusive breastfeeding support in health facilities in Malawi

Alinane Linda Nyondo-Mipando, Mai-Lei Woo Kinshella, Sangwani Salimu, Brandina Chiwaya et al. • International Breastfeeding Journal (2021)

Abstract Background Exclusive breastfeeding is widely accepted as a key intervention with proven efficacy for improving newborn survival. Despite international commitments and targets to support and promote breastfeeding, there are still ga...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13006-021-00418-9

CuddleCard: Protocol for a randomized controlled trial evaluating the effect of providing financial support to low-income mothers of preterm infants on parental caregiving in the neonatal intensive care unit (NICU)

Margaret McConnell, Alya Alsager, Plyce Fuchu, Shrivaths Sriprasad et al. • BMC Pediatrics (2025)

Abstract Background Preterm birth is a leading cause of childhood mortality and developmental disabilities, with persistent socioeconomic disparities in incidence and outcomes. Maternal presence during prolonged neonatal intensive care unit...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12887-025-05621-9

Research and Public Policy

Leonard D. Eron • PEDIATRICS (1996)

Professor Hyman has reviewed for us all the research that has been done on the effects of corporal punishment in the schools.1 It is actually a meager record because of the reasons he has mentioned, many of them ethical, demographic, and re...

OPENALEX DOI: https://doi.org/10.1542/peds.98.4.821

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

Philipp Arnold, Fanni Annamária Boros, Jochen Mattner, Gerald Seidel et al. • Journal of Extracellular Biology (2025)

ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellu...

DOAJ Open Access (DOAJ) DOI: 10.1002/jex2.70093

Spatio-temporal analysis of childhood vaccine uptake in Nigeria: a hierarchical Bayesian Zero-inflated Poisson approach

Temitayo Victor Lawal, Kehinde Adebola Atoloye, Ayo Stephen Adebowale, Adeniyi Francis Fagbamigbe • BMC Pediatrics (2023)

Abstract Background Globally, child mortality and morbidity remain a serious health challenge and infectious diseases are the leading causes. The use of count models together with spatial analysis of the number of doses of childhood vaccine...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12887-023-04300-x

Artificial intelligence for pediatric height prediction using large-scale longitudinal body composition data

Dohyun Chun, Hae Woon Jung, Jongho Kang, Woo Young Jang et al. • Digital Health (2025)

Objective We developed a precise, reliable artificial intelligence (AI) model for predicting the future height of children and adolescents based on anthropometric and body composition data. Materials and Methods We used an extensive longitu...

DOAJ Open Access (DOAJ) DOI: 10.1177/20552076251395975

Systematic review and meta-analysis reveal positive therapeutic effects of music in brain damage rehabilitation

Laura Navarro, Laura Navarro, Laura Navarro, Nour El Zahraa Mallah et al. • Frontiers in Integrative Neuroscience (2026)

Brain damage (BD) caused by stroke, traumatic brain injury (TBI), or neurodegenerative conditions often results in persistent cognitive, motor, and emotional impairments. Music-based interventions (MI) have been explored as adjunctive rehab...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnint.2026.1720473

Cranial ultrasonographic findings in newborns exposed to SARS-CoV-2: a single-centre cross-sectional analysis

Bruna Scalia, Marco Andrea Nicola Saporito, Laura Mauceri, Alessandro Valerio Saporito et al. • Italian Journal of Pediatrics (2024)

Abstract Background SARS-CoV-2’s potential consequences on the developing brain are still unknown. The aim of this study was to describe cranial ultrasonographic (cUS) findings in a population of newborns exposed to SARS-CoV-2 born at San M...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13052-024-01826-3

Efficacy, safety, and quality of life 4 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A in the phase 3 GENEr8-1 trial

Andrew D. Leavitt, Johnny Mahlangu, Priyanka Raheja, Emily Symington et al. • Research and Practice in Thrombosis and Haemostasis (2024)

Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rpth.2024.102615

Timing of menarche and pubertal growth patterns using the QEPS growth model

Jenni Gårdstedt-Berghog, Jenni Gårdstedt-Berghog, Aimon Niklasson, Agneta Sjöberg et al. • Frontiers in Pediatrics (2024)

ObjectivesTo explore the timing of menarche, postmenarcheal growth, and to investigate the impact of various variables on menarcheal age and postmenarcheal and pubertal growth.Study DesignThis longitudinal community population-based study a...

DOAJ Open Access (DOAJ) DOI: 10.3389/fped.2024.1438042

The influence of family in children’s feeding difficulties: an integrative review

Pâmela Gracielle da Fonseca, António Raposo, Nada Alqarawi, Ibrahim Alasqah et al. • Frontiers in Pediatrics (2025)

BackgroundFeeding difficulties, such as limited appetite, selective eating, and food phobia, affect caregivers' ability to provide adequate nutrition to children. These issues impact 25%–40% of non-neurodivergent children and up 80% of neur...

DOAJ Open Access (DOAJ) DOI: 10.3389/fped.2025.1609714

Engaging Nurses in Effective Cost of Care Conversations to Address Cancer-Related Financial Toxicity: Results from an Exploratory Survey

Jean S. Edward, Amanda Thaxton Wiggins, Louis G. Baser, Haafsah Fariduddin et al. • Current Oncology (2025)

Few evidence-based trainings exist on how to equip healthcare providers, particularly nurses, with the skills to engage in cost of care conversations with patients/caregivers to mitigate the impact of cancer-related financial toxicity. This...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol32010033

Procalcitonin-guided antibiotic therapy for pediatrics with infective disease: A updated meta-analyses and trial sequential analysis

Peng Li, JiaLe Liu, Junjun Liu • Frontiers in Cellular and Infection Microbiology (2022)

ObjectiveWe aimed to evaluate the effect of procalcitonin (PCT) guided therapy on antibiotic exposure in pediatric patients with infectious disease.MethodsWe performed an updated systematic review and meta-analysis of randomized controlled ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2022.915463

Beverage Consumption Patterns and Their Association with Metabolic Health in Adults from Families at High Risk for Type 2 Diabetes in Europe—The Feel4Diabetes Study

Paris Kantaras, Niki Mourouti, Theodora Mouratidou, Ekaterini Chatzaki et al. • Endocrines (2024)

In total, 3274 adults (65.2% females) from six European countries were included in this cross-sectional analysis using data from the baseline assessment of the Feel4Diabetes study. Anthropometric, sociodemographic, dietary and behavioral da...

DOAJ Open Access (DOAJ) DOI: 10.3390/endocrines5030020

TRACK-CF prospective cohort study: Understanding early cystic fibrosis lung disease

Eva Steinke, Eva Steinke, Eva Steinke, Olaf Sommerburg et al. • Frontiers in Medicine (2023)

BackgroundLung disease as major cause for morbidity in patients with cystic fibrosis (CF) starts early in life. Its large phenotypic heterogeneity is partially explained by the genotype but other contributing factors are not well delineated...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.1034290