Academic Articles & Research Papers

Characterization of the oral microbiome in the diverse South African population by PacBio HiFi sequencing.

SequelTools: a suite of tools for working with PacBio Sequel raw sequence data

Abstract Background PacBio sequencing is an incredibly valuable third-generation DNA sequencing method due to very long read lengths, ability to detect methylated bases, and its real-time sequencing methodology. Yet, hitherto no tool was av...

A novel and accelerated method for integrated alignment and variant calling from short and long reads

BackgroundIntegrating short- and long-read sequencing technologies has become a promising approach for achieving accurate and comprehensive genomic analysis. Although short-read sequencing (Illumina, etc.) offers high base accuracy and cost...