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Copper exposure association with prevalence of non-alcoholic fatty liver disease and insulin resistance among US adults (NHANES 2011–2014)

Chen Chen, Qi Zhou, Ruiyue Yang, Zhu Wu et al. • Ecotoxicology and Environmental Safety (2021)

Background: Excessive copper (Cu) has risky effect on insulin resistance (IR), oxidative stress and inflammation. Instead, some studies reported serum Cu to be protective for non-alcoholic fatty liver disease (NAFLD). The aim of this study ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ecoenv.2021.112295

Higher calorie intake with adequate exercise is associated with reduced mortality compared with low-calorie diet with equivalent exercise: An observational study from NHANES based on the 2020–2025 Dietary Guidelines for Americans

Hanghang Gan, Yu Yan, Shanshan Jia, Yingqiang Guo et al. • Experimental Gerontology (2025)

Object: To explore the effects of different combinations of calorie intake and exercise on all-cause, cardiovascular and cancer mortality. Methods: Data from the National Health and Nutrition Examination Survey (NHANES) were analyzed. Weigh...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.112805

Mediating role of neutrophil-percentage-to-albumin ratio in the association between stroke and heart failure among U.S. adults

Yan Zhao, Tingting Chen, Conghua Ji, Yuxin Shang et al. • Experimental Gerontology (2026)

Background: Stroke is an independent risk factor for heart failure (HF), and they are both linked to systemic inflammation. The neutrophil-percentage-to-albumin ratio (NPAR) is a novel inflammation biomarker. However, it is unclear whether ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.113010

The AST/ALT ratio as a mediator of heavy metal exposure and diabetic kidney disease (DKD) risk: A NHANES study

Yu Li, Juan Chai, Jinjuan Chen, Jiayin Du et al. • Scientific Reports (2025)

Abstract The potential impact of heavy metal exposure on the progression of diabetic kidney disease (DKD) remains a subject of scientific inquiry. While some studies have hinted at a correlation, definitive evidence is still lacking. It is ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-23843-w

Development and validation of an online dynamic nomogram based on the atherogenic index of plasma to screen nonalcoholic fatty liver disease

Hewei Peng, Junchao Zhang, Xianhua Huang, Miao Xu et al. • Lipids in Health and Disease (2023)

Abstract Background Nonalcoholic fatty liver disease (NAFLD), a common liver disease worldwide, can be reversed early in life with lifestyle and medical interventions. This study aimed to develop a noninvasive tool to screen NAFLD accuratel...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12944-023-01808-0

Construction of the cancer patients’ database based on the US National Health and Nutrition Examination Survey (NHANES) datasets for cancer epidemiology research

Jinyoung Moon, Yongseok Mun • BMC Medical Research Methodology (2025)

Abstract Background The US National Health and Nutrition Examination Survey (NHANES) dataset does not include a specific question or laboratory test to confirm a history of cancer diagnosis. However, if straightforward variables for cancer ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12874-025-02478-5