Academic Articles & Research Papers

ROS/Enzyme Dual-Responsive Drug Delivery System for Targeted Colorectal Cancer Therapy: Synergistic Chemotherapy, Anti-Inflammatory, and Gut Microbiota Modulation

Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related mortality, driven by chronic inflammation, gut microbiota dysbiosis, and complex tumor microenvironment interactions. Current therapies are limited by systemic toxicit...

Polyphenols and Pharmacological Screening of a Monarda fistulosa L. dry Extract Based on a Hydrodistilled Residue By-Product

This study aimed to determine the composition and content of polyphenols in the dry extract obtained from the hydrodistilled residue by-product of the wild bergamot (Monarda fistulosa L., Lamiaceae Martinov family) herb (MFDE) and to evalua...

HIV viral protein expression disrupts bone tissue homeostasis in mice.

Automated temporal analysis reveals stress-induced protracted feeding regulated by mesolimbic dopamine in mice.

Electroacupuncture attenuates high-salt-induced hypertension by modulating neuronal excitability and proteomic signatures in the paraventricular nucleus of mice.

Body Size and Cranial Shape Differentiation in Urban and Rural House Mice (Mus musculus domesticus).

The insulin gene in humans and mice: evolution, regulation, and sex-specific mechanisms of diabetes susceptibility.

Identification of flupirtine as a candidate against liver fibrosis in mice: Preserving mitochondria quality by suppressing calpain 1/complex I/mtROS axis via targeting asparagine synthase.

Whole-body glucose tolerance is impaired in male and female congenic mice lacking nicotinamide nucleotide transhydrogenase (NNT).

Zdhhc14 promotes pyroptosis in the dorsal root ganglion of oxaliplatin-induced peripheral neuropathy mice by enhancing GBP5 palmitoylation and suppressing its ubiquitination.

A disynaptic trigeminal circuit for the transformation and integration of oral chemesthesis in male mice.

Mapping the hepatic regulatory landscape of estradiol in gonadectomized obese female and male mice at single-nucleus resolution.

Live combined bifidobacterium attenuates rivaroxaban-associated colonic bleeding in mice: evidence for a substantial gut microbiota-dependent component.

Postoperative inulin supplementation is associated with microbiota remodeling and improved colonic anastomotic healing in LPS-primed mice.

Ameliorative Effects and Underlying Molecular Mechanisms of Nootkatone in DSS-Induced Ulcerative Colitis in Mice.

Natural compound ailanthone alleviates herpes simplex keratitis in mice by inhibiting HSV-1 replication.

β7-Integrin worsens diet-induced metabolic syndrome in mice by altering intestinal lipid handling and colonic inflammatory monocyte infiltration.

A step beyond: age and sex-dependent changes in multidimensional locomotor and gait patterns of voluntary motion of C57BL/6 mice.

Characterization of depot-specific adipokine release in diet-induced obese mice reveals a distinct secretion profile in paracardial adipose tissue.

A local sympathetic-immune axis inhibits melanoma growth in mice by dictating adrenergic control.