Academic Articles & Research Papers

Polymeric Nanomedicines in Diabetic Wound Healing: Applications and Future Perspectives

Zeyao Chen,1 Kakei Chan,1 Xin Li,1,2 Li Gong,3 Yingjie Ma,4 Chiwen Huang,5 Yan Lu,6 Li Wang,1 Chunli Piao1 1Department of Endocrinology, Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, Shenzhen, People’s Republic of ...

Therapeutic potential of hyaluronic acid hydrogel combined with bone marrow stem cells-conditioned medium on arthritic rats’ TMJs

Abstract Conditioned media (CM) is derived from mesenchymal stem cells (MSC) culture and contains biologically active components. CM is easy to handle and reduces inflammation while repairing injured joints. Combination therapy of the CM wi...

Injectable mesoporous bioactive glass/sodium alginate hydrogel loaded with melatonin for intervertebral disc regeneration

Intervertebral disc degeneration (IDD) is a major contributing factor to both lower back and neck pain. As IDD progresses, the intervertebral disc (IVD) loses its ability to maintain its disc height when subjected to axial loading. This fai...

Datasets describing hydrogel properties and cellular metrics for modeling of tumor dormancy

Breast cancer dormancy is an underlying challenge toward targeting and controlling metastatic recurrence and disease progression. Development of engineered, well-defined in vitro models is necessary to systematically recapitulate tumor dorm...

Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy

Abstract Background Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe, therapy-refractory condition driven by ferroptotic disruption of jawbone-derived mesenchymal stem cells (MSCs) biology. We dissect this mechanism to va...

Injectable hyaluronic acid-collagen derived hydrogel based on component biomimetic as vitreous substitute

Vitrectomy is a common clinical treatment for fundus disease. Due to the non-renewable nature of the vitreous, artificial vitreous are usually required to replace natural vitreous to perform functions post operation. Silicone oil and gas, a...

Acoustic Cell Patterning for Structured Cell‐Laden Hydrogel Fibers/Tubules

Abstract Cell‐laden hydrogel fibers/tubules are one of the fundamentals of tissue engineering. They have been proven as a promising method for constructing biomimetic tissues, such as muscle fibers, nerve conduits, tendon and vessels, etc. ...

Fundamentals and Advances in Stimuli-Responsive Hydrogels and Their Applications: A Review

This review summarizes the fundamental concepts, recent advancements, and emerging trends in the field of stimuli-responsive hydrogels. While numerous reviews exist on this topic, the field continues to evolve dynamically, and certain resea...

Continuous monitoring biosensors for advanced healthcare and environmental applications: challenges, material innovations and future directions

This review critically discusses the development of continuous monitoring biosensors and the technological developments that have facilitated the transition from one-off or periodic measurement sensors to longer-term, connected and autonomo...

Development of a pro-angiogenic stem cell-derived vascular cell extracellular matrix-decorated hyaluronic acid hydrogel.

Pore-Throat-Adaptive Transport and Flow-Redistribution Mechanisms of Deformable Hydrogel Particles in Tight Reservoirs of the Ordos Basin

Tight reservoirs commonly exhibit strong pore-throat confinement and flow heterogeneity, which cause injected water to preferentially migrate through connected high-conductivity pathways while a large fraction of movable fluids remains unde...

Programmable self-gelling hydrogel powders: from hemostatic dressings to integrated therapeutic platforms for complex wound management.

Hydrogel-Controlled Electropolymerization of Polynorepinephrine through Confined Noncovalent Self-Assembly.