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Showing 18 of 18 academic articles

CRISPR/Cas9 for hepatitis B virus infection treatment

Bo Cai, Shixue Chang, Yuhan Tian, Shuai Zhen • Immunity, Inflammation and Disease (2023)

Abstract Hepatitis B virus (HBV) infection remains a global health challenge. Despite the availability of effective preventive vaccines, millions of people are at risk of cirrhosis and hepatocellular carcinoma. Current drug therapies inhibi...

DOAJ Open Access (DOAJ) DOI: 10.1002/iid3.866

siRNA Functionalized Lipid Nanoparticles (LNPs) in Management of Diseases

Tutu Kalita, Saba Abbasi Dezfouli, Lalit M. Pandey, Hasan Uludag • Pharmaceutics (2022)

RNAi (RNA interference)-based technology is emerging as a versatile tool which has been widely utilized in the treatment of various diseases. siRNA can alter gene expression by binding to the target mRNA and thereby inhibiting its translati...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics14112520

Investigating the performance of the fluorescent sensor g-C3N4/Fe/Cu in detecting the Tenofovir drug

Nafiseh Hajian Afarani, Fatemeh Keshavarzi, Kahin Shahanipour, Seyed Amir Zarei • Scientific Reports (2025)

Abstract Tenofovir is an antiviral drug that prevents the replication of AIDS and hepatitis B viruses. To minimize the harmful side effects of the drug on the body, it is essential to determine its precise concentration in the blood. Fluore...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-08877-4

Study on seroprevalence of hepatitis delta in a regional hospital in western Turkey

Sukran Kose, Gulfem Ece, Ayhan Gozaydin, Melda Turken • Journal of Infection in Developing Countries (2012)

Introduction: Hepatitis delta virus (HDV) is an incomplete virus dependent on hepatitis B virus (HBV) for its multiplication. It can infect individuals with active HBV infection and cause severe liver disease. It is less prevalent than hepa...

DOAJ Open Access (DOAJ) DOI: 10.3855/jidc.1749

MBOAT7-TMC4 rs641738 Is Not Associated With the Risk of Hepatocellular Carcinoma or Persistent Hepatitis B Infection

Peng Wang, Ying Li, Lu Li, Rong Zhong et al. • Frontiers in Oncology (2021)

ObjectiveA hot genetic variant, rs641738 within the membrane-bound O-acyltransferase domain containing 7(MBOAT7) and transmembrane channel-like 4 (TMC4), was recently reported to be associated with several liver diseases. However, the resul...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2021.639438

Behavioral Differences in the Preference for Hepatitis B Virus Vaccination: A Discrete Choice Experiment

Na Guo, Jian Wang, Stephen Nicholas, Elizabeth Maitland et al. • Vaccines (2020)

Understanding behavioral factors differences in the preferences for vaccinations can improve predictions of vaccine uptake rates and identify effective policy interventions to increase the demand for vaccinations. In this study, 353 adults ...

DOAJ Open Access (DOAJ) DOI: 10.3390/vaccines8030527

Case reports of latent HBV hepatitis in patients after neurosurgical treatment for hypothalamic and pituitary tumors

Kuniyasu Niizuma, Yoshikazu Ogawa, Takayuki Kogure, Teiji Tominaga • BMC Infectious Diseases (2020)

Abstract Background Hepatitis B virus (HBV) infection is a major public health problem worldwide. More than 2 billion people have been exposed to HBV, and about 257 million individuals are chronic carriers of HBV. HBV reactivation has been ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12879-020-04971-2