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Academic Articles & Research Papers
Showing 20 of 33 academic articles
Eunyoung Park, Jiho Lee, Jeong-Han Kim, Joon-Kwan Moon • Applied Biological Chemistry
(2023)
Abstract The crystal structures of the pyribencarb E and Z stereoisomers were determined using single-crystal X-ray crystallography. The isomers were confirmed a single data respectively by crystal analysis, LC-UVD mass spectrometry, and NM...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13765-023-00770-w
Majid Asadi-Samani, Navid Jamali, Javad Saffari-Chaleshtori, Korosh Ashrafi-Dehkordi • Journal of Ardabil University of Medical Sciences
(2022)
Background & objectives: Cyclin-dependent kinase 2 (CDK-2) is a serine/threonine protein kinase with regulatory activity in the cell cycle. Inhibitors of this protein are the treatment of choice for a variety of cancers by stopping the cell...
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Open Access (DOAJ)
Lorenzo Pedroni, Daniel Zocchi Doherty, Chiara Dall’Asta, Gianni Galaverna et al. • Ecotoxicology and Environmental Safety
(2024)
Mycotoxins are known environmental pollutants that may contaminate food and feed chains. Some mycotoxins are regulated in many countries to limit the trading of contaminated and harmful commodities. However, the so-called emerging mycotoxin...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ecoenv.2024.116167
Maria Angelova, Petko Alov, Ivanka Tsakovska, Dessislava Jereva et al. • Molecules
(2025)
Scoring functions are key elements in docking protocols as they approximate the binding affinity of a ligand (usually a small bioactive molecule) by calculating its interaction energy with a biomacromolecule (usually a protein). In this stu...
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Open Access (DOAJ)
DOI: 10.3390/molecules30132777
Cheng J, Huang Y • Journal of Inflammation Research
(2026)
Jian Cheng, Yangfeng Huang Department of Traditional Chinese Medicine, Sichuan Provincial People’s Hospital, School of Medicine,University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of ChinaCorrespond...
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Open Access (DOAJ)
Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences
(2022)
Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...
DOAJ
Open Access (DOAJ)
DOI: 10.17179/excli2021-4534
Lili Tian, Lili Tian, Jian Sun, Hong Jiang et al. • Frontiers in Cellular and Infection Microbiology
(2025)
IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) is a major clinical challenge due to its virulence and multidrug resistance. Antivirulence strategies targeting key pathogenic mechanisms without affecting bacterial viability p...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fcimb.2025.1686699
Atanu Singha Roy, Amit Kumar Dinda, Nitin Kumar Pandey, Swagata Dasgupta • Journal of Pharmaceutical Analysis
(2016)
The interaction of baicalein with bovine serum albumin (BSA) was investigated with the help of spectroscopic and molecular docking studies. The binding affinity of baicalein towards BSA was estimated to be in order of 105 M−1 from fluoresce...
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Open Access (DOAJ)
DOI: 10.1016/j.jpha.2016.04.001
Chantel L. Rabusin, Hylton B. Menz, Jodie A. McClelland, Angela M. Evans et al. • Journal of Foot and Ankle Research
(2019)
Abstract Background Mid-portion Achilles tendinopathy is a common musculoskeletal condition characterised by degeneration of the Achilles tendon, which causes pain and disability. Multiple non-surgical treatments have been advocated for thi...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13047-019-0325-2
Aki Sugano, Yutaka Takaoka, Haruyuki Kataguchi, Mika Ohta et al. • Microorganisms
(2022)
Previously, we developed a mathematical model via molecular simulation analysis to predict the infectivity of six SARS-CoV-2 variants. In this report, we aimed to predict the relative risk of the recent new variants of SARS-CoV-2 based on o...
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Open Access (DOAJ)
DOI: 10.3390/microorganisms10102090
Hao Tang, Ting Qin, Zhiwen Yan, Changqing Li et al. • Frontiers in Neuroscience
(2026)
ObjectiveDioctyl terephthalate (DOTP), a widely used plasticizer in food packaging and environmental materials, has raised concerns regarding its potential impact on human health. This study aims to investigate the neurotoxicity-related mec...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnins.2026.1783807
Wenjie Wu, Rongjing Xia, Si Ma, Zenglei Hu et al. • Poultry Science
(2026)
Newcastle disease (ND) caused by Newcastle disease virus (NDV) infection is a highly contagious avian disease that causes substantial threat to the global poultry industry. Emodin (EMO), a member of the free anthraquinone compounds derived ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.psj.2026.107180
Shijiao Zhang, Yanding Su, Ao Han, He Qi et al. • Pharmaceuticals
(2025)
Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/ph18081111
Angelo Vedani, Martin Smiesko, Morena Spreafico, Ourania Peristera et al. • ALTEX: Alternatives to Animal Experimentation
(2009)
The VirtualToxLab™ is an in silico tool for predicting the toxic (endocrine-disrupting) potential of drugs, chemicals and natural products. It is based on a fully automated protocol and calculates the binding affinity of any molecule of int...
DOAJ
Open Access (DOAJ)
DOI: 10.14573/altex.2009.3.167
Lufei Chen, Chaoxian Dai, Zhenfang Wu, Yuhan Lin et al. • Journal of Xenobiotics
(2026)
Accumulating epidemiological evidence links ambient PM2.5 exposure to elevated Parkinson’s disease (PD) risk, yet the neurotoxicity triggered by PM2.5 multi-pollutant mixtures under real co-exposure scenarios remains insufficiently elucidat...
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Open Access (DOAJ)
DOI: 10.3390/jox16060184
Muhammad Jawad, Saurabh Bhatia, Ahmed Al-Harrasi, Sana Ullah et al. • Heliyon
(2024)
The study examined the antimicrobial and antioxidant potential of pure Acetyl-11-keto-β-boswellic acid (AKBA), boswellic acid (70%) and AKBA loaded nanoparticles as topical polymeric films. The optimized concentration (0.05 % w/v) of pure A...
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Open Access (DOAJ)
DOI: 10.1016/j.heliyon.2024.e31671
Clarin Hayes, Fahrul Nurkolis, Dewa Ayu Agus Sri Laksemi, Sanghyun Chung et al. • Molecules
(2023)
Coffee became a beverage that was in demand in the world and consequently produced millions of tons of coffee byproducts namely coffee silverskin (CS). Unutilized CS will be waste and cause environmental pollution such as greenhouse gas emi...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules28207037
Na Song, Huili Xia, Yaoru Xie, Shuaikang Guo et al. • Synthetic and Systems Biotechnology
(2025)
Tyrosol is an important component of pharmaceuticals, nutraceuticals, and cosmetics, and their biosynthetic pathways are currently a hot research topic. d-Erythrose 4-phosphate is a key precursor for the biosynthesis of tyrosol in Saccharom...
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Open Access (DOAJ)
DOI: 10.1016/j.synbio.2024.11.007
Yashuai Wu, Ruiyang Yin, Wenjing Tian, Wanqiu Zhao et al. • Foods
(2026)
Umami taste in lager beer not only determined body fullness and the backbone of aftertaste, but also affected the controllability and interpretability of flavor expression across the entire brewing process. Based on stage-wise sampling, pep...
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Open Access (DOAJ)
DOI: 10.3390/foods15040641
Md. Rakhibul Hasan, Surid Mohammad Chowdhury, Md. Abdul Aziz, Asif Shahriar et al. • Informatics in Medicine Unlocked
(2021)
In this in silico study, thirty-five ciprofloxacin analogs were docked to the active site of DNA gyrase, the prime target of ciprofloxacin type antibiotics. Prior to docking all the structures were optimized using MM2 force field parameters...
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Open Access (DOAJ)
DOI: 10.1016/j.imu.2021.100748