Academic Articles & Research Papers

Medical Informatics

Information technology has been revolutionizing the everyday life of the common man, while medical science has been making rapid strides in understanding disease mechanisms, developing diagnostic techniques and effecting successful treatmen...

A STUDY ON MEDICAL INFORMATICS

Medical informatics, a rapidly evolving field, plays a pivotal role in improving healthcare delivery, patient outcomes, and the overall healthcare system. This abstract provides an overview of the key concepts, applications, and impacts of ...

Clinically feasible NODDI characterization of glioma using multiband EPI at 7 T

Recent technological progress in the multiband echo planer imaging (MB EPI) technique enables accelerated MR diffusion weighted imaging (DWI) and allows whole brain, multi-b-value diffusion imaging to be acquired within a clinically feasibl...

Non-parametric synergy modeling of chemical compounds with Gaussian processes

Abstract Background Understanding the synergetic and antagonistic effects of combinations of drugs and toxins is vital for many applications, including treatment of multifactorial diseases and ecotoxicological monitoring. Synergy is usually...

Growing functional modules from a seed protein via integration of protein interaction and gene expression data

Abstract Background Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the organization of PPI networks is the existence of dense...

Data describing the poor outcome associated with a breast cancer diagnosis in the post-weaning period

Postpartum breast cancer (PPBC) - which according to new data, can extend to 5–10 years after the birth - are estimated to represent 35–55% of all cases of breast cancer in women younger than 45 years. Increasing clinical evidence indicates...

From BIG Data Center to China National Center for Bioinformation

Rural Telemedicine Use Before and During the COVID-19 Pandemic: Repeated Cross-sectional Study

BackgroundThe COVID-19 pandemic has led to a notable increase in telemedicine adoption. However, the impact of the pandemic on telemedicine use at a population level in rural and remote settings remains unclear. ObjectiveThis st...

Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions

Technology-based interventions to promote health are expanding rapidly. Assessing the preliminary efficacy of these interventions can be achieved by employing single-case experiments (sometimes referred to as n-of-1 studies). Although singl...

Digital Exclusion and Cognitive Function in Elderly Populations in Developing Countries: Insights Derived From 2 Longitudinal Cohort Studies

BackgroundCognition disorders not only lead to adverse health consequences but also contribute to a range of socioeconomic challenges and diminished capacity for performing routine daily activities. In the digital era, understanding the imp...

Memantine for Refractory Obsessive-Compulsive Disorder: Protocol for a Pragmatic, Double-blind, Randomized, Parallel-Group, Placebo-Controlled, Monocenter Trial

BackgroundObsessive-compulsive disorder (OCD) is a psychiatric syndrome characterized by unwanted and repetitive thoughts and repeated ritualistic compulsions for decreasing distress. Symptoms can cause severe distress and functional impair...

LocateP: Genome-scale subcellular-location predictor for bacterial proteins

Abstract Background In the past decades, various protein subcellular-location (SCL) predictors have been developed. Most of these predictors, like TMHMM 2.0, SignalP 3.0, PrediSi and Phobius, aim at the identification of one or a few SCLs, ...

Software Engineering in Medical Informatics

This study presents a systematic literature review to provide overall view of the application of Software Engineering (SE) in Medical Informatics (MI) field. Articles published from 2010 to 2019 from seven selected databases (Emerald, PubMe...

The Cornerstones of Medical Informatics

The changes in the health care system over the next decade are goint to make the last 20 years seem like good old days of relative stability. We will continue to see new drugs, new devices, and new techniques; however, the true megachanges ...

MEDICAL INFORMATICS

Medical informatics, according to two US researchers, "is emerging as a distinct academic entity." More cynically one could say that the academic world has realised that grants are to be had, jobs created, and money made from building datab...

Predictors of community acquired childhood pneumonia among 2–59 months old children in the Amhara Region, Ethiopia

Abstract Background Worldwide, pneumonia is the third leading cause of death in under 5 years children. Ethiopia is ranked 4th out of 15 countries having the highest burdens of the death rate among under-five children due to pneumonia. Rega...

Infodemiological data concerning silicosis in the USA in the period 2004–2010 correlating with real-world statistical data

This article reports data concerning silicosis-related web-activities using Google Trends (GT) capturing the Internet behavior in the USA for the period 2004–2010. GT-generated data were then compared with the most recent available epidemio...

Patient-reported treatment outcomes and safety of direct-to-consumer teledermatology for finasteride treatment in male androgenetic alopecia: A cross-sectional study

Objective The use of direct-to-consumer (DTC) teledermatology platforms has increased, particularly for androgenetic alopecia (AGA). However, little is known about the efficacy and safety of these platforms. This study aimed to investigate ...

Data on genotypic distribution and linkage disequilibrium of several ANRIL polymorphisms in hemodialysis patients

A long non-coding RNA called ANRIL located on chromosome 9p21.3 has been identified as a novel genetic factor associated with cardiovascular disease. Investigation of several single nucleotide polymorphisms (SNPs) of Noncoding Antisense RNA...

A review of medical education and medical informatics

Physicians have considerable difficulty collecting and interpreting information from patients, dealing with the uncertainties associated with diagnosing and treating their patients, communicating precisely with one another, keeping up to da...