Academic Articles & Research Papers

The influence of frailty syndrome on medication adherence among elderly patients with hypertension

Beata Jankowska-Polańska,1 Krzysztof Dudek,2 Anna Szymanska-Chabowska,3 Izabella Uchmanowicz1 1Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 2Department of Logistic and Transport Systems, Faculty of ...

Preoperative and intraoperative assessment of myometrial invasion in patients with FIGO stage I non-endometrioid endometrial carcinoma—a large-scale, multi-center, and retrospective study

Abstract Introduction Myometrial invasion is a prognostic factor for lymph node metastases and decreased survival in non-endometrioid endometrial carcinoma patients. Herein, we explored the mode of myometrial invasion diagnosis in FIGO stag...

Evaluating the Psychological Impacts Related to COVID-19 of Vietnamese People Under the First Nationwide Partial Lockdown in Vietnam

This is the first time in Vietnam that people have undergone “social distancing” to minimize the spreading of infectious disease, COVID-19. These deliberate preemptive strategies may have profound impacts on the mental health of the populat...

Spatiotemporal analysis of hospitalizations, mortality and access to intravenous thrombolysis for ischemic stroke in Southern Brazil

Abstract Background Globally, stroke is a leading cause of mortality and disability, affecting approximately 15 million people annually. This study aimed to analyze hospitalizations, deaths, and thrombolysis for ischemic stroke in Southern ...

Age and Ageing During the COVID-19 Pandemic; Challenges to Public Health and to the Health of the Public

The distribution of the SARS-CoV-2 virus has reached pandemic proportions. While COVID-19 can affect anyone, it is particularly hazardous for those with “co-morbidities.” Older age is an especially strong and independent risk factor for hos...

Digital biomarkers: Convergence of digital health technologies and biomarkers

Over the last decade, increasing digitization across the healthcare continuum has revolutionized medical research, diagnostics, and therapeutics. This digitization has led to rapid advancements in the development and adoption of digital hea...

Pathway analysis of the impact of family function and self-efficacy on depression and anxiety in patients undergoing in vitro fertilization-embryo transfer

Abstract Background Patients undergoing assisted reproductive technology (ART) experience significant psychological distress due to infertility, with depression and anxiety being the most common manifestations. This study investigates the i...

Methodological approaches of health technology assessment

Neuropsychological Health Technologies

The article reveals the problem of neuropsychological technologies for maintaining, strengthening and developing human health from early to adulthood as a set of corrective and developmental measures to ensure the relationship of an optimal...

Barriers and facilitators of retention in care after cervical cancer screening: patients’ and healthcare providers’ perspectives

Abstract Background Cervical cancer continues to threaten women’s health, especially in low-resource settings. Regular follow-up after screening and treatment is an effective strategy for monitoring treatment outcomes. Consequently, underst...

Muscle Bmal1 is Dispensable for the Progress of Neurogenic Muscle Atrophy in Mice

Global deletion of aryl hydrocarbon receptor nuclear translocator-like ('Arntl'; also known as 'Bmal1'), a molecular component of the circadian clock, resulted in an extreme loss of muscle mass. However, the functional role of muscle BMAL1 ...

A hybrid plasmid formed by recombination of a virulence plasmid and a resistance plasmid in Klebsiella pneumoniae

Objective: The emergence of multidrug-resistant (MDR) and hypervirulent Klebsiella pneumoniae (hvKP) facilitates simultaneous dissemination of virulence and resistance in a single event, which poses serious threat to public health. Methods:...

European Law and New Health Technologies

Health is a matter of fundamental importance in European societies, both as a human right in itself, and as a factor in a productive workforce and therefore a healthy economy. New health technologies promise improved quality of life for pat...

European network for Health Technology Assessment, EUnetHTA: Planning, development, and implementation of a sustainable European network for Health Technology Assessment

OBJECTIVES: The European network on Health Technology Assessment (EUnetHTA) aimed to produce tangible and practical results to be used in the various phases of health technology assessment and to establish a framework and processes to suppo...

Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

Abstract Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not ...

Inspiratory pressure waveform influences time to failure, respiratory muscle fatigue, and metabolism during resistive breathing

Abstract Increased ventilatory work beyond working capacity of the respiratory muscles can induce fatigue, resulting in limited respiratory muscle endurance (Tlim). Previous resistive breathing investigations all applied square wave inspira...

Displacement and Emplacement of Health Technology

The provision of “closer-to-patient” services has increased in most industrialized countries. However, the migration of services in non-traditional health care settings implies redefining the role of technical and human entities and transfo...

Instruments measuring the quality of life among people living with type 2 diabetes mellitus in India: a systematic review protocol

Introduction Type 2 diabetes mellitus affects an individual’s quality of life (QoL); and there are multiple instruments that can be used to measure QoL. The purpose of this systematic review is to identify the existing instruments that have...

Mapping the acute trajectory of sport-related concussion outcomes across symptoms, cognition, and blood biomarkers

Sport-related concussion (SRC) and its potential neurological sequela represent an emerging global health concern, requiring improved recovery management and strategies for return-to-play (RTP) to enhance brain health in athletes. Given the...

Antimicrobial compound from Trichoderma harzianum, an endophytic fungus associated with ginger (Zingiber officinale)

Background: Genus Trichoderma of fungal kingdom are largely used as biological control agents due to broad-spectrum activity against plant pathogens. Objective: This study aimed to investigate Trichoderma harzianum, an endophytic fungus obt...