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Academic Articles & Research Papers
Showing 20 of 284 academic articles
Sneha Pallatt, Sibin Nambidi, Subhamay Adhikary, Antara Banerjee et al. • Oncology Reviews
(2025)
Lynch syndrome (LS) is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes. These mutations result in frameshift alterations, leading to the accumulation of errors within microsatellites. Individua...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/or.2025.1549416
Zelin Tian, Chen Xu, Peijun Yang, Zhibin Lin et al. • Frontiers in Immunology
(2022)
Hepatocellular carcinoma(HCC) is the sixth most common cancer in the world and is usually caused by viral hepatitis (HBV and HCV), alcoholic, and non-alcoholic fatty liver disease(NAFLD). Viral hepatitis accounts for 80% of HCC cases worldw...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fimmu.2022.984728
Angelo Corti, Angelina Sacchi, Anna Maria Gasparri, Matteo Monieri et al. • Journal of Nanobiotechnology
(2021)
Abstract Background Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature. We prepared bi- o...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12951-021-00871-y
A. Yu. Yakovlev, Anastasia A. Kruglikova, Sergey I. Chernysh • Entomological Review
(2019)
Blow flies (Diptera, Calliphoridae) and their medical applications have attracted the attention of biologists and doctors for more than a century. The best known is the use of “surgical maggots” in the treatment of infected wounds and ulcer...
OPENALEX
DOI: https://doi.org/10.1134/s0013873819030023
Nanxia Zhao, Nicola L. Francis, Shuang Song, Vladyslav Kholodovych et al. • Advanced NanoBiomed Research
(2022)
Neuroinflammation is one of the hallmarks contributing to Parkinson's disease (PD) pathology, where microglial activation occurs as one of the earliest events, triggered by extracellular α‐synuclein (aSYN) binding to the cluster of differen...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/anbr.202100120
Pier P. Piccaluga, Pier P. Piccaluga, Pier P. Piccaluga, Alessandra Weber et al. • Frontiers in Microbiology
(2018)
Tumor metabolism has been the object of several studies in the past, leading to the pivotal observation of a consistent shift toward aerobic glycolysis (so-called Warburg effect). More recently, several additional investigations proved that...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmicb.2018.01233
Amoolya Kandettu, Divya Adiga, Vasudha Devi, Padmanaban S. Suresh et al. • Genes and Diseases
(2022)
Ovarian cancer (OC) is one of the most common and fatal types of gynecological cancer. OC is usually detected at the advanced stages of the disease, making it highly lethal. miRNAs are single-stranded, small non-coding RNAs with an approxim...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.gendis.2021.12.026
Joshua George Thomas, Mohammed Ayyub, Lovely M. Annamma, Prathibha Prasad et al. • Biomedicines
(2026)
Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progressio...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/biomedicines14102234
Hamid Reza Rahimi, Mahmoud Reza Jaafari, Amir Hooshang Mohammadpour, Khalil Abnous et al. • Asia Pacific Journal of Medical Toxicology
(2015)
Alcoholic liver disease (ALD) is the main cause of chronic liver disease across the world and can lead to fibrosis and cirrhosis. The etiopathogenesis of ALD is related to ethanol-induced oxidative stress, glutathione reduction, abnormal me...
DOAJ
Open Access (DOAJ)
DOI: 10.22038/apjmt.2015.3983
Zongrui Tong, Yong Gao, Huang Yang, Weilin Wang et al. • View
(2021)
Abstract Catalytic therapy utilizing special substances (e.g., hydrogen peroxide and glucose) in tumor sites has attracted wide interest to achieve tumor‐specific therapy or improve the efficacy of other treatments. Benefiting from the sele...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/VIW.20200133
Srivastava RK, Sapra L • Journal of Inflammation Research
(2022)
Rupesh K Srivastava, Leena Sapra Immunoporosis Lab, Department of Biotechnology, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, IndiaCorrespondence: Rupesh K Srivastava, Tel +91 11-26593548, Email rupesh_srivastava13@ya...
DOAJ
Open Access (DOAJ)
Hussein Sabit, Shaimaa Nazir, Shimaa Abdel-Ghany, Osama A. Said et al. • Asian Pacific Journal of Cancer Biology
(2019)
Being the most common cause of female deaths worldwide, breast cancer (BC) is intensively studied over the last two decades. In the present investigation, we evaluated the promoter methylation of three cancer-related genes; PARP-1, p21, and...
DOAJ
Open Access (DOAJ)
DOI: 10.31557/apjcb.2019.4.1.1-5
Dan Lu, Yuan Chen, Min Jiang, Jie Wang et al. • Nature Communications
(2023)
Abstract KRAS mutations are broadly recognized as promising targets for tumor therapy. T cell receptors (TCRs) can specifically recognize KRAS mutant neoantigens presented by human lymphocyte antigen (HLA) and mediate T cell responses to el...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41467-023-42010-1
Majid Sadeghi Moghadam, Hosein Azimian, Jalil Tavakol Afshari, Mohammad Taghi Bahreyni Toossi et al. • Stem Cells International
(2023)
Background. Radiotherapy is a crucial treatment for most malignancies. However, it can cause several side effects, including the development of secondary malignancies due to radiation-induced genomic instability (RIGI). The aim of this stud...
DOAJ
Open Access (DOAJ)
DOI: 10.1155/2023/9991656
Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer
(2024)
Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/jitc-2023-008450
Xinbo Wang, Jiaying Miao, Sizhen Wang, Rongxi Shen et al. • Molecular Cancer
(2022)
Abstract Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical features. Me...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12943-022-01596-8
Vanessa Maria Nunes Roque, Nora Manoukian Forones • Arquivos de Gastroenterologia
(2006)
RACIONAL: O câncer colorretal é a quarta causa de câncer no Brasil e o 5-fluourouracil uma das principais drogas usadas no tratamento adjuvante e paliativo dessa doença. A toxicidade da quimioterapia e as alterações de qualidade de vida, ca...
DOAJ
Open Access (DOAJ)
DOI: 10.1590/S0004-28032006000200007
Katya Carbone, Fabio Gervasi, Latipa Kozhamzharova, Nazgul Altybaeva et al. • Frontiers in Molecular Biosciences
(2023)
Plants, with their range of pharmacologically active molecules, represent the most promising source for the production of new anticancer drugs and for the formulation of adjuvants in chemotherapy treatments to reduce drug content and/or cou...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmolb.2023.1157558
Zhen Li, Yannik Gehlen, Yannik Gehlen, Fabian Heizmann et al. • Frontiers in Bioengineering and Biotechnology
(2020)
Discogenic low back pain (LBP) is a main cause of disability and inflammation is presumed to be a major driver of symptomatic intervertebral disc degeneration (IDD). Anti-inflammatory agents are currently under investigation as they demonst...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fbioe.2020.00583
Chih‐Li Chen, Yu‐Shuen Tsai, Yen‐Hua Huang, Yuh‐Jin Liang et al. • Hepatology Communications
(2018)
Lymphoid enhancer factor 1 (LEF1) activity is associated with progression of several types of cancers. The role of LEF1 in progression of hepatocellular carcinoma (HCC) remains poorly known. We investigated LEF1 expression in HCC and its in...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/hep4.1229