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Evaluating key predictors of breast cancer through survival: a comparison of AFT frailty models with LASSO, ridge, and elastic net regularization

Senyefia Bosson-Amedenu, Emmanuel Ayitey, Francis Ayiah-Mensah, Luyton Asare • BMC Cancer (2025)

Abstract Background Frailty models are extensively utilized in survival analysis to address unobserved heterogeneity among individuals. However, selecting the most robust model for survival prediction, especially in the context of high-dime...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12885-025-14040-z

Modeling antiretroviral therapy adherence among people living with HIV: a cross-sectional study at Pantang Hospital, Ghana

Eric Nyarko, Irene A. Kretchy, Grace Lovia Allotey-Babington, Adwoa Oforiwaa Kwakye et al. • BMC Infectious Diseases (2026)

Abstract Background Poor adherence to antiretroviral therapy (ART) continues to undermine HIV treatment outcomes in sub-Saharan Africa, including Ghana. Objective This study aimed to quantify ART treatment adherence among people living with...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12879-026-13836-z

Mathematical Modeling of Leptospirosis With Misdiagnosis

Japheth Musingila Mwongela, Caroline Kanyiri, Virginia Kitetu • Journal of Applied Mathematics (2026)

Leptospirosis is a widespread zoonotic bacterial disease that continues to pose a major public health challenge, particularly in developing countries where it causes substantial morbidity, mortality, and economic losses. A key problem in co...

DOAJ Open Access (DOAJ) DOI: 10.1155/jama/5513951

Increased prevalence of loneliness and associated risk factors during the COVID-19 pandemic: findings from the Canadian Longitudinal Study on Aging (CLSA)

Susan A. Kirkland, Lauren E. Griffith, Urun Erbas Oz, Mary Thompson et al. • BMC Public Health (2023)

Abstract Background Older adults have been disproportionately impacted by COVID-19 and related preventative measures undertaken during the pandemic. Given clear evidence of the relationship between loneliness and health outcomes, it is impe...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-023-15807-4

Implementation of the therapeutic use of hydroxyurea for sickle cell disease management in resource-constrained settings: a systematic review of adoption, cost and acceptability

Joyce Gyamfi, Temitope Ojo, Dorice Vieira, Nessa Ryan et al. • BMJ Open (2020)

Objectives Mortality associated with sickle cell disease (SCD) is high in many low- and middle-income countries (LMICs). Hydroxyurea, a medicine to effectively manage SCD, is not widely available in resource-constrained settings. We identif...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2020-038685

Traffic Fatalities and Urban Infrastructure: A Spatial Variability Study Using Geographically Weighted Poisson Regression Applied in Cali (Colombia)

Harvy Vivas Pacheco, Diego Rodríguez-Mariaca, Ciro Jaramillo, Andrés Fandiño-Losada et al. • Safety (2023)

The mobility plan and the road infrastructure works implemented, together with the Bus Rapid Transit (BRT) connected bus system in its first two phases, generated optimistic expectations about the reduction of lethal crashes in the city. Th...

DOAJ Open Access (DOAJ) DOI: 10.3390/safety9020034

Designing tax incentives and disincentives for urban cultural heritage conservation: a behavioral policy framework

Zijian Yao • Journal of Asian Architecture and Building Engineering (2026)

This study proposes a systematic policy framework that leverages special tax measures to steer stakeholder behavior toward urban cultural heritage conservation. Integrating comparative policy analysis, microeconomic modeling, systematic pol...

DOAJ Open Access (DOAJ) DOI: 10.1080/13467581.2026.2639088

Evaluating the impact of urban traffic patterns on air pollution emissions in Dublin: a regression model using google project air view data and traffic data

Pavlos Tafidis, Mehdi Gholamnia, Payam Sajadi, Sruthi Krishnan Vijayakrishnan et al. • European Transport Research Review (2024)

Abstract Air pollution is a significant and pressing environmental and public health concern in urban areas, primarily driven by road transport. By gaining a deeper understanding of how traffic dynamics influence air pollution, policymakers...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12544-024-00671-z

The influence of roadway characteristics and built environment on the extent of over-speeding: An exploration using mobile automated traffic camera data

Boniphace Kutela, Frank Ngeni, Cuthbert Ruseruka, Tumlumbe Juliana Chengula et al. • International Journal of Transportation Science and Technology (2025)

Over-speeding is a pivotal factor in fatal traffic crashes globally, necessitating robust speed management strategies to augment road safety. In 2021, the National Highway Traffic Safety Administration reported over 12 000 speed-related fat...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijtst.2024.03.003

The Digital Transformation in Health: How AI Can Improve the Performance of Health Systems

África Periáñez, Ana Fernández Del Río, Ivan Nazarov, Enric Jané et al. • Health Systems & Reform (2024)

Mobile health has the potential to revolutionize health care delivery and patient engagement. In this work, we discuss how integrating Artificial Intelligence into digital health applications focused on supply chain operation, patient manag...

DOAJ Open Access (DOAJ) DOI: 10.1080/23288604.2024.2387138

Yes! Kissing Too… The Child Would Not Be Hurt in Any Way: Social Constructions of Child Sexual Abuse in the Ga Community in Ghana

Ummu Markwei • Qualitative Sociology Review (2019)

The United Nations Convention on the Rights of the Child obligates nations to protect children from all forms of abuse including sexual. However, child sexual abuse is a complex phenomenon which is difficult to understand as a result of cul...

DOAJ Open Access (DOAJ) DOI: 10.18778/1733-8077.15.3.06

Disability-inclusive community development: A case of a community garden in Limpopo province in South Africa

Brian Tigere, Theresa Moyo • African Journal of Disability (2022)

Background: Persons with disabilities living in rural areas are marginalised and excluded in most developmental initiatives in South Africa. They face many economic, political and social problems; hence, improving their quality of life is a...

DOAJ Open Access (DOAJ) DOI: 10.4102/ajod.v11i0.850

Identifying research particiaption effects through qualitative methods: Feedback from Research Engagement Consultants involved in a pediatric mental health comparative effectiveness trial

Elisabeth A. Stelson, Mallory Bolenbaugh, Briana Woods-Jaeger, Cassidy Branch et al. • SSM: Qualitative Research in Health (2021)

Research participation effects (RPEs)—effects due to study design rather than study intervention—have long been acknowledged as a research phenomenon. Identifying RPEs is crucial to understanding the true effects of an intervention and outc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ssmqr.2021.100023

Challenges and experience of the Ethiopian rural health extension program: implications for reform and revitalization

Taddese Alemu Zerfu, Amare Abera Tareke, Sibhatu Biadgilign • BMC Health Services Research (2023)

Abstract Background Despite remarkable gains over the past decade, mounting evidence suggests that Ethiopia’s rural health extension program (HEP) is facing serious implementation challenges. We investigated the current and potential future...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-023-10253-9

What Evidence Underlies Clinical Practice in Paediatric Surgery? A Systematic Review Assessing Choice of Study Design.

Benjamin Allin, Nicholas Aveyard, Timothy Campion-Smith, Eleanor Floyd et al. • PLoS ONE (2016)

ObjectiveIdentify every paediatric surgical article published in 1998 and every paediatric surgical article published in 2013, and determine which study designs were used and whether they were appropriate for robustly assessing intervention...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0150864

From Mental Health Crisis to Existential Human Suffering: The Role of Self-Transcendence in Contemporary Mindfulness

Renata Cueto de Souza, Charles Scott • Religions (2022)

Our paper addresses the so-called college mental health crisis and the adoption of the strategy of mindfulness-based interventions. We offer a critique of their underlying medical–therapeutic paradigm by engaging the notion of self-transcen...

DOAJ Open Access (DOAJ) DOI: 10.3390/rel13080681

Heat transfer by three types of hot pack and its implication on the flexibility of the lower back: a randomized, controlled trial

Paulina Fuentes-León, Natalia Jara-Poblete, Pía Bastías-Sánchez, Kaio Fernando Vitzel et al. • Fisioterapia e Pesquisa (2016)

ABSTRACT The use of hot pack is a common superficial thermotherapy strategy and one of its benefits is the increase of muscle flexibility. However, there is a lack of information about the effects of the heat pack alone, without being used ...

DOAJ Open Access (DOAJ) DOI: 10.1590/1809-2950/15088923022016