Academic Articles & Research Papers

Unsupervised machine learning identifies distinct ALS molecular subtypes in post-mortem motor cortex and blood expression data

Abstract Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic heterogeneity. Machine learning approaches have previously been utilised for patient stratification in ALS as they can disentangle complex disease lands...

AI-Driven Integration of Deep Learning With Lung Imaging, Functional Analysis, and Blood Gas Metrics for Perioperative Hypoxemia Prediction

This viewpoint article explores the transformative role of artificial intelligence (AI) in predicting perioperative hypoxemia through the integration of deep learning with multimodal clinical data, including lung imaging, pulmonary function...

Biomaterial Engineering for Spatiotemporal Regulation of Exosome Functions: From Design Principles to Key Applications in Regenerative Medicine

As natural nanoscale intercellular messengers, exosomes exhibit considerable potential in modulating inflammation, angiogenesis, immunoregulation, and tissue remodeling, making them attractive candidates for regenerative medicine. However, ...

Anti-inflammation lipid nanoparticles enable localized mRNA therapy for inflammatory bowel disease.

Targeting pepsin provides superior protection to acid suppression in reflux-associated airway inflammation and lung dysfunction.

Dengue Virus Pathogenesis: Innate Immune Signaling and Cell Death Receptor Pathways.