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Smart integrated nanosystems for biomedical applications:critical issues and perspectives

Domenico Lombardo, Luigi Pasqua, Mikhail A. Kiselev • Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali (2019)

During the last decades the progresses of nanoscience and nanotechnology for biomedical application stimulated the transition from traditional drug delivery systems to the development of smart integrated nanosystems with stimuli-responsive ...

DOAJ Open Access (DOAJ) DOI: 10.1478/AAPP.97S2A14

Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Supachai Sakkhachornphop, Sudarat Hadpech, Tanchanok Wisitponchai, Chansunee Panto et al. • Viruses (2018)

Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, AnkGAG1D4, showed a negative effect on the viral assembly of the HIV...

DOAJ Open Access (DOAJ) DOI: 10.3390/v10110625

Identification and Validation of PLOD2 as an Adverse Prognostic Biomarker for Oral Squamous Cell Carcinoma

Yawei Sun, Shuai Wang, Xingwei Zhang, Zhuhao Wu et al. • Biomolecules (2021)

Background: Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a key enzyme that catalyzes the hydroxylation of lysine, plays a crucial role in the progression of several solid tumors. However, its spatial expression profile and pr...

DOAJ Open Access (DOAJ) DOI: 10.3390/biom11121842

Varieties of Mushrooms and their Nutraceutical Importance: A Systematic Review

Debasmita Chatterje, Dipankar Halder, Satadal Das • Journal of Clinical and Diagnostic Research (2021)

Introduction: Around 2000 species of mushrooms exist in nature, of which hardly 25 varieties are accepted as edible in nature. “Nutraceuticals” are food substances that are associated with immense health benefits and also hinder the deve...

DOAJ Open Access (DOAJ) DOI: 10.7860/JCDR/2021/47240.14660

Atrioesophageal fistula after radiofrequency catheter ablation for atrial fibrillation: clinical case

Vladislav V. Gaskin, Anna A. Gaskina, Amir G. Masri, Valentin A. Nеchaev et al. • Клиническая практика (2026)

BACKGROUND: Atrioesophageal fistula is a rare complication following radiofrequency catheter ablation for atrial fibrillation and is associated with high mortality. Clinical manifestations of atrioesophageal fistula are nonspecific and may ...

DOAJ Open Access (DOAJ) DOI: 10.17816/clinpract695545

Quantitative Detection of High-Strength Bolt Loosening Based on Self-Magnetic Flux Leakage

Shangkai Liu, Kai Tong, Fengmin Chen, Senhua Zhang et al. • Buildings (2026)

The reliability of high-strength bolted connections is critical to the safety of large-scale engineering structures. This study proposes a non-contact quantitative method for detecting bolt loosening based on the self-magnetic flux leakage ...

DOAJ Open Access (DOAJ) DOI: 10.3390/buildings16030497

Response Analysis on Electrical Pulses under Severe Nuclear Accident Temperature Conditions Using an Abnormal Signal Simulation Analysis Module

Kil-Mo Koo, Jin-Ho Song, Sang-Baik Kim, Kwang-Il Ahn et al. • Science and Technology of Nuclear Installations (2012)

Unlike design basis accidents, some inherent uncertainties of the reliability of instrumentations are expected while subjected to harsh environments (e.g., high temperature and pressure, high humidity, and high radioactivity) occurring in s...

DOAJ Open Access (DOAJ) DOI: 10.1155/2012/656590

A Review of Thermal Safety and Management of Second-Life Batteries: Cell Screening, Pack Configuration and Health Estimation

Md Imran Hasan, Gang Lei, Dylan Lu, Pablo Poblete Durruty • Batteries (2026)

Electric vehicle (EV) adoption is generating a rapidly increasing stream of retired lithium-ion batteries for second-life deployment. However, thermal safety concerns continue to limit their reuse. This paper reviews second-life battery (SL...

DOAJ Open Access (DOAJ) DOI: 10.3390/batteries12030099

Why do emergency department clinicians miss acute aortic syndrome? A case series and descriptive analysis

Rachel McLatchie, Sarah Wilson, Matthew Reed, Francoise Ticehurst et al. • Emergency Care Journal (2023)

Objectives: To understand why the diagnosis of AAS is missed in the ED, and to characterise the presenting features of cases in which a diagnosis of AAS was missed. Methods: A retrospective case series cohort study was performed, identif...

DOAJ Open Access (DOAJ) DOI: 10.4081/ecj.2023.11153

Association of triglyceride glucose-body roundness index and body roundness index with incident sarcopenia among Chinese older adults: A nationwide cohort study

Yu -Yang Ma, Hai-Yan Li, Ruo-Nan Yao, Gong Cheng et al. • Experimental Gerontology (2025)

Background: The relationship between TyG-BRI, BRI, and the sarcopenia definition proposed by the Asian Working Group for Sarcopenia (AWGS) in 2019 remains unclear. This research focused on exploring the relationship between the TyG-BRI inde...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.112946

Nutritional status, literacy, and risk factors of malnutrition in the population over 50 years of age - findings from the SHARE project

Tereza Vágnerová, Olga Dvořáčková, Eva Topinková • Clinical Nutrition Open Science (2024)

Summary: Background & Aims: The transition from middle age to old age (from adults aged 50–55 years to older seniors aged 75–80 years) represents a critical period in terms of changes in body composition, i.e., increase in body fat per...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nutos.2024.01.006

Cracking rare disorders: a new minimally invasive RNA-seq protocol

Laurenz De Cock, Erika D’haenens, Lies Vantomme, Lynn Backers et al. • npj Genomic Medicine (2025)

Abstract RNA sequencing (RNA-seq) has become key to complementing exome and genome sequencing for variant interpretation. We present a minimally invasive RNA-seq protocol using short-term cultured peripheral blood mononuclear cells (PBMCs) ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41525-025-00502-7

miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology (2021)

Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-021-01127-x

Lipofuscin: Wear Pigment or Alarm Signal for Cardiac AlloGraft Vasculopathy?

Anca Otilia Farcas, Mihai Ciprian Stoica, Septimiu Voidazan, Carmen Corina Radu et al. • Diagnostics (2026)

Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics16152432

DETECTION & DIFFERENTIATION OF SOFT TISSUE INJURIES IN ADVANCE MAGNETIC RESONANCE IMAGING (MRI)

Muhammad Qaisar Pervaiz, Ayesha Younas, Altaf Pervez Qasim • Journal of University Medical & Dental College (2015)

ABSTRACT BACKGROUND: Radiology is the application of the science of diagnostic imaging to questions of clinical and medicolegal practice. Forensic medicine refers to the application of medical knowledge in the collection of medical evidence...

DOAJ Open Access (DOAJ)

A pilot study of mitochondrial genomic ancestry in admixed Brazilian patients with type 1 diabetes

Lívia Leite Ferreira, Anna Beatriz Rodrigues Gonçalves, Igor Josué Barbosa Adiala, Silvia Loiola et al. • Diabetology & Metabolic Syndrome (2024)

Abstract Interactions between multiple genes and environmental factors could be related to the pathogenesis of type 1 diabetes (T1D). The Brazilian population results from different historical miscegenation events, resulting in a highly div...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13098-024-01342-8

Protocol to measure human IL-6 secretion from CAR T cell-primed macrophage and monocyte lineage cells in vitro and in vivo using humanized mice

Thao Nguyen, Toshiaki Yoshikawa, Yusuke Ito, Hitomi Kasuya et al. • STAR Protocols (2024)

Summary: Chimeric antigen receptor (CAR) T cell therapy often causes serious toxicities, such as cytokine release syndrome (CRS), mainly due to interleukin-6 (IL-6) secreted by monocyte lineage cells. Here, we describe a protocol to generat...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.xpro.2024.103423

Health Technologies: Transforming Scientific Knowledge into Human Health

Hüseyin Okan Durmuş • Zenodo (CERN European Organization for Nuclear Research) (2026)

Health technologies are commonly associated with medical devices, digital health platforms, robotics, and artificial intelligence. However, this perspective captures only the most visible dimension of a much broader concept. This study exam...

OPENALEX cc-by DOI: https://doi.org/10.5281/zenodo.21826977