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Academic Articles & Research Papers
Showing 20 of 7,733 academic articles
Pei-Iun Hsieh, Te-Hsuan Huang, Jeng-Min Chiou, Jen-Hau Chen et al. • Epidemiology and Health
(2024)
The Taiwan Initiative for Geriatric Epidemiological Research (TIGER) was founded in 2011 to elucidate the interrelationships among various predictors of global and domain-specific cognitive impairment, with the aim of identifying older adul...
DOAJ
Open Access (DOAJ)
DOI: 10.4178/epih.e2024057
Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali et al. • Cell Reports
(2018)
Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compar...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.celrep.2018.10.070
Xiao Lin, Jun-Jie Yang, Bei Huang, Peng-Xin Wang et al. • Experimental Gerontology
(2026)
Background: BMI cannot distinguish fat distribution and may mask the true effects of different fat depots on bone mineral density (BMD). To investigate sex- and age-specific associations between fat distribution and BMD and its mediating ro...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2026.113301
Claudia Contreras, Diana Paola Córdoba‐Rodríguez, Robinson Cuadros, José Ricardo Jauregui et al. • JCSM Communications
(2026)
ABSTRACT Background Secondary sarcopenia driven by chronic disease, acute illness, immobilization, malnutrition or treatment‐related factors contributes to functional decline, falls, disability, readmission and mortality. In Colombia, uneve...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/rco2.70051
Maria Luiza Lima-Silva, Karen Cecília Lima Torres, Juliana Vaz de Melo Mambrini, Nathalia Coimbra Brot et al. • Experimental Gerontology
(2024)
Immunosenescence is a phenomenon caused by changes in the immune system, and part of these changes involves an increase in circulating immunological biomarkers, a process known as “Inflammaging.” Inflammaging can be associated with many dis...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2024.112433
Lin-lin Yao, Xiao-ting Ma, Fang-bo Li, Lin-yi Zheng et al. • Experimental Gerontology
(2026)
Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2026.113057
Yan Zhang, Ling Jiang, Jinyu Zhu, Sijia Shen et al. • BMJ Paediatrics Open
(2026)
Background Proper discharge preparation by family caregivers is essential for improving the growth and development of preterm infants and lowering their readmission rates. Within China’s unique family cultural context, intergenerational car...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjpo-2026-004695
PMC: PMC13691880
Sillas Oliveira Leonel Júnior, Mateus Dias Antunes, Ramon Gustavo de Moraes Ovando, Ana Paula Serra de Araújo et al. • Geriatrics, Gerontology and Aging
(2024)
OBJECTIVE: To analyze the behavior of blood pressure and heart rate in elderly people practicing physical exercises in Maringá, Paraná, Brazil. METHODS: 70 elderly volunteers were evaluated, 41 women and 29 men, with a mean age of 67.2 ± 6....
DOAJ
Open Access (DOAJ)
DOI: 10.5327/Z2447-211520171700042
Meng Zhang, Ping He, Zhigang Bian • Frontiers in Molecular Neuroscience
(2021)
Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are progressive and ultimately fatal. NDD onset is influenced by several fa...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnmol.2021.685143
Lauren M. Herr, Swagata Mukhopadhyay, Olivia M. Anderson, Tucker H. Couch et al. • Communications Biology
(2026)
Abstract DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary structures that present a substant...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s42003-026-09966-4
Lan Chen, Jing-Xin Zhang, Dong-Ge Liu, Hong-Gang Liu • Diagnostics
(2023)
This paper illustrates a rare syndrome of multiple endocrine neoplasia type 2A (MEN2A) in a family of three generations. In our case, the father, son and one daughter developed phaeochromocytoma (PHEO) and medullary thyroid carcinoma (MTC) ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/diagnostics13050955
Victoria McArthur, Susan Everington, Martyn Patel • Archives of Gerontology and Geriatrics Plus
(2024)
Introduction: Dementia is a global health priority, with an increasing percentage of overall hospital bed days occupied by people with dementia (PWD). This combined with increased demand and availability of complex scanning means that there...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.aggp.2024.100087
Yi-Shan Jiang, Hong Shi, Yu-Ting Kang, Ji Shen et al. • BMC Geriatrics
(2023)
Abstract Background The World Health Organization (WHO) has proposed healthy aging framework, supposing that intrinsic capacity (IC), environment and their interaction may have influence on functional ability (FA). It was still unclear how ...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-023-04089-5
Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight et al. • BMJ Open
(2023)
Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the un...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjopen-2023-077772
Yan Zhao, Tingting Chen, Conghua Ji, Yuxin Shang et al. • Experimental Gerontology
(2026)
Background: Stroke is an independent risk factor for heart failure (HF), and they are both linked to systemic inflammation. The neutrophil-percentage-to-albumin ratio (NPAR) is a novel inflammation biomarker. However, it is unclear whether ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2025.113010
Erden Eren, Jeannie-Marie Leoutsakos, Juan Troncoso, Constantine G. Lyketsos et al. • Cells
(2022)
The hallmarks of Alzheimer’s disease (AD) pathology are senile plaques containing amyloid-beta (Aβ) and neurofibrillary tangles containing hyperphosphorylated tau. Additional pathologies often co-exist, whereas multiple pathogenic mechanism...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cells11030436
Hiroshi Murayama, Benjamin A. Shaw • Journal of Obesity & Metabolic Syndrome
(2017)
This article reviewed studies to investigate the association between trajectories of body mass index (BMI) and mortality among older adults. Investigators conducted a systematic search of published peer-reviewed literature in the PubMed dat...
DOAJ
Open Access (DOAJ)
DOI: 10.7570/jomes.2017.26.3.181
Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen et al. • BMC Geriatrics
(2025)
Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. Due to their frailty status, comorbidity burden can serve as a useful predictive indicator of vul...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-025-05721-2
Sadayuki Ito, Yoshihito Sakai, Kei Ando, Hiroaki Nakashima et al. • Asian Spine Journal
(2023)
Study Design Retrospective study. Purpose Cervical laminoplasty is safe and effective for treating cervical myelopathy but has a higher frequency of postoperative axial pain compared to other methods. Several studies have reported on the ca...
DOAJ
Open Access (DOAJ)
DOI: 10.31616/asj.2022.0120
Leon G. Martens, Jiao Luo, Fleur L. Meulmeester, Nadia Ashrafi et al. • Antioxidants
(2020)
The antioxidant vitamin E (α-tocopherol, α-TOH) protects lipids from oxidation by reactive oxygen species. We hypothesized that lifestyle factors associate with vitamin E metabolism marked by urinary α-tocopheronolactone hydroquinone (α-TLH...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/antiox9121280