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Showing 20 of 7,962 academic articles
Lin-lin Yao, Xiao-ting Ma, Fang-bo Li, Lin-yi Zheng et al. • Experimental Gerontology
(2026)
Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2026.113057
Yan Zhang, Ling Jiang, Jinyu Zhu, Sijia Shen et al. • BMJ Paediatrics Open
(2026)
Background Proper discharge preparation by family caregivers is essential for improving the growth and development of preterm infants and lowering their readmission rates. Within China’s unique family cultural context, intergenerational car...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjpo-2026-004695
PMC: PMC13691880
Sillas Oliveira Leonel Júnior, Mateus Dias Antunes, Ramon Gustavo de Moraes Ovando, Ana Paula Serra de Araújo et al. • Geriatrics, Gerontology and Aging
(2024)
OBJECTIVE: To analyze the behavior of blood pressure and heart rate in elderly people practicing physical exercises in Maringá, Paraná, Brazil. METHODS: 70 elderly volunteers were evaluated, 41 women and 29 men, with a mean age of 67.2 ± 6....
DOAJ
Open Access (DOAJ)
DOI: 10.5327/Z2447-211520171700042
Meng Zhang, Ping He, Zhigang Bian • Frontiers in Molecular Neuroscience
(2021)
Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are progressive and ultimately fatal. NDD onset is influenced by several fa...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnmol.2021.685143
Lan Chen, Jing-Xin Zhang, Dong-Ge Liu, Hong-Gang Liu • Diagnostics
(2023)
This paper illustrates a rare syndrome of multiple endocrine neoplasia type 2A (MEN2A) in a family of three generations. In our case, the father, son and one daughter developed phaeochromocytoma (PHEO) and medullary thyroid carcinoma (MTC) ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/diagnostics13050955
Junqi Yang, Yumin Ma, Jiang Liu, Qingtian Zhu et al. • Experimental Gerontology
(2024)
The aging of pancreatic beta cells is closely associated with various diseases, such as impaired glucose tolerance, yet the underlying regulatory mechanisms remain unclear. In this study, we screened young and aged mouse pancreatic beta cel...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2024.112633
Victoria McArthur, Susan Everington, Martyn Patel • Archives of Gerontology and Geriatrics Plus
(2024)
Introduction: Dementia is a global health priority, with an increasing percentage of overall hospital bed days occupied by people with dementia (PWD). This combined with increased demand and availability of complex scanning means that there...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.aggp.2024.100087
Yi-Shan Jiang, Hong Shi, Yu-Ting Kang, Ji Shen et al. • BMC Geriatrics
(2023)
Abstract Background The World Health Organization (WHO) has proposed healthy aging framework, supposing that intrinsic capacity (IC), environment and their interaction may have influence on functional ability (FA). It was still unclear how ...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-023-04089-5
Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight et al. • BMJ Open
(2023)
Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the un...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjopen-2023-077772
Yan Zhao, Tingting Chen, Conghua Ji, Yuxin Shang et al. • Experimental Gerontology
(2026)
Background: Stroke is an independent risk factor for heart failure (HF), and they are both linked to systemic inflammation. The neutrophil-percentage-to-albumin ratio (NPAR) is a novel inflammation biomarker. However, it is unclear whether ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2025.113010
Yan Cai, Wei Zhu, Chenshu Wu, Yan Jiang • BMC Public Health
(2026)
Abstract Background Falls are a leading global cause of injury and mortality in older adults, necessitating understanding risk factor interplay for prevention. This study aims to investigate complex interactions among risk factors associate...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12889-026-27192-9
Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen et al. • BMC Geriatrics
(2025)
Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. Due to their frailty status, comorbidity burden can serve as a useful predictive indicator of vul...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-025-05721-2
Sadayuki Ito, Yoshihito Sakai, Kei Ando, Hiroaki Nakashima et al. • Asian Spine Journal
(2023)
Study Design Retrospective study. Purpose Cervical laminoplasty is safe and effective for treating cervical myelopathy but has a higher frequency of postoperative axial pain compared to other methods. Several studies have reported on the ca...
DOAJ
Open Access (DOAJ)
DOI: 10.31616/asj.2022.0120
Leon G. Martens, Jiao Luo, Fleur L. Meulmeester, Nadia Ashrafi et al. • Antioxidants
(2020)
The antioxidant vitamin E (α-tocopherol, α-TOH) protects lipids from oxidation by reactive oxygen species. We hypothesized that lifestyle factors associate with vitamin E metabolism marked by urinary α-tocopheronolactone hydroquinone (α-TLH...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/antiox9121280
Kazuki Uemura, Takehiko Doi, Kota Tsutsumimoto, Sho Nakakubo et al. • Journal of Cachexia, Sarcopenia and Muscle
(2020)
Abstract Background Bioelectrical impedance analysis (BIA)‐derived phase angle is expected to be an efficient prognostic marker of health adverse events with aging as an alternative of muscle mass. We aimed to examine the predictive ability...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/jcsm.12492
Alessandra da Silva Oliveira, Claudia Teixeira-Arroyo • Geriatrics, Gerontology and Aging
(2024)
Objetivo: Verifi car o efeito de um programa de exercícios físicos funcionais, associados ao componente lúdico, nos sintomas depressivos, na capacidade de realização das atividades da vida diária (AVD) e nos sintomas de dor de idosos instit...
DOAJ
Open Access (DOAJ)
Merve Tarhan, Pınar Doğan • Journal of Nursology
(2026)
Objective: Despite the increasing ageing population, caring for older adults is not a highly preferred field of nursing in Türkiye and the world; studies examining the attitudes and behaviors of new graduate nurses towards older adult care ...
DOAJ
Open Access (DOAJ)
DOI: 10.17049/jnursology.1509812
Ling Tong, Zhe Cong, Long Tian, Jingjing Zhang et al. • Frontiers in Microbiology
(2021)
It is challenging to trace the complicated individual-based variations of HIV-specific immunocompetence shift during the successful antiretroviral therapy (ART) era. Using eight rhesus monkeys simulating a longitudinal stage-dependent cohor...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmicb.2021.704449
Jin Guo, Andrew Wister, Barbara Mitchell, Merril Silverstein et al. • BMC Geriatrics
(2026)
Abstract Objectives Based on defamilization, individualization, and contingent intergenerational solidarity theories, this study developed a cultural defamilization framework. Longitudinal data were used to explore changes in the associatio...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-026-07449-z
Tetsuro Tago, Jun Toyohara • Molecules
(2018)
Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules23020300