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Low-grade chronic inflammation and transcriptomics: how molecular pharmacognosy can help find new natural treatment alternatives—a narrative review

Massimo Fioranelli, Maria Grazia Roccia, Bianca Przybylek, Francesca Romana Sconci et al. • Beni-Suef University Journal of Basic and Applied Sciences (2024)

Abstract Background The inflammatory response is fundamental to the maintenance of an organism’s physiological homeostasis. Inflammation is controlled by a series of biological events driven by specific inflammatory molecules. When inflamma...

DOAJ Open Access (DOAJ) DOI: 10.1186/s43088-024-00506-9

In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity

Andre Luis Dias Araujo Mazzari, Mariella Guimarães Lacerda, Flora Aparecida Milton, Flora Aparecida Milton et al. • Frontiers in Pharmacology (2022)

Many medicinal plants species from European -such as Artemisia absinthium, Equisetum arvense, Lamium album, Malva sylvestris, Morus nigra, Passiflora incarnata, Frangula purshiana, and Salix alba- as well as Latin American traditions -such ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2022.826395

The Utilization of Plant-Material-Loaded Vesicular Drug Delivery Systems in the Management of Pulmonary Diseases

Bongani Sannyboy Lukhele, Kokoette Bassey, Bwalya Angel Witika • Current Issues in Molecular Biology (2023)

Medicinal plants have been utilized to treat a variety of conditions on account of the bioactive properties that they contain. Most bioactive constituents from plants are of limited effectiveness, due to poor solubility, limited permeabilit...

DOAJ Open Access (DOAJ) DOI: 10.3390/cimb45120624

Efficacy, safety, and quality of life 4 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A in the phase 3 GENEr8-1 trial

Andrew D. Leavitt, Johnny Mahlangu, Priyanka Raheja, Emily Symington et al. • Research and Practice in Thrombosis and Haemostasis (2024)

Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rpth.2024.102615

Progress and Prospects of Non-Canonical NF-κB Signaling Pathway in the Regulation of Liver Diseases

Li Tao, Xiaomeng Ren, Wenhui Zhai, Zheng Chen • Molecules (2022)

Non-canonical nuclear factor kappa B (NF-κB) signaling pathway regulates many physiological and pathological processes, including liver homeostasis and diseases. Recent studies demonstrate that non-canonical NF-κB signaling pathway plays an...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27134275

Increased expression of glutathione peroxidase 3 prevents tendinopathy by suppressing oxidative stress

Haruka Furuta, Mari Yamada, Takuya Nagashima, Shuichi Matsuda et al. • Frontiers in Pharmacology (2023)

Tendinopathy, a degenerative disease, is characterized by pain, loss of tendon strength, or rupture. Previous studies have identified multiple risk factors for tendinopathy, including aging and fluoroquinolone use; however, its therapeutic ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2023.1137952

Fumaric acid regulates morphine tolerance in bone cancer pain through spinal MrgC receptor modulation

Sijie Liu, Minghao Tang, Jing Zhao, Lulu Zhang et al. • Pakistan Journal of Pharmaceutical Sciences (2026)

Background: Bone cancer pain (BCP) represents a debilitating complication that profoundly impacts patient quality of life and predisposes to psychological comorbidities, including depression and anxiety. Objectives: To investigate the effec...

DOAJ Open Access (DOAJ) DOI: 10.36721/PJPS.2026.39.8.233.1

Enteric Coating Enhances the Biopharmaceutical Performance of a Silica–Lipid Formulation of Abiraterone Acetate

Ali Taheri, Ruba Almasri, Anthony Wignall, Felicia Feltrin et al. • Pharmaceutics (2025)

Background/Objectives: Lipid-based formulations are widely used to enhance the oral bioavailability of poorly water-soluble drugs. However, for weakly basic drugs with higher solubility under acidic conditions, precipitation and recrystalli...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics17101289

Caracterização dos medicamentos descartados no ponto de coleta em uma universidade do nordeste brasileiro

Sharon Paoli Bias Ramos, Gabriel Rodrigues Martins de Freitas, Silvana Teresa Lacerda Jales • Jornal de Assistência Farmacêutica e Farmacoeconomia (2025)

Objetivo: analisar o perfil pós-consumo dos medicamentos descartados pela comunidade universitária no coletor disponibilizado no Centro de Ciências da Saúde da Universidade Federal da Paraíba. Métodos: O projeto de extensão Descarta CIM ins...

DOAJ Open Access (DOAJ) DOI: 10.22563/2525-7323.2025.v10.e00255

Palladium-Catalyzed Stereoselective Construction of 1,3-Stereocenters Displaying Axial and Central Chirality via Asymmetric Alkylations

Aiqi Xue, Xingfu Wei, Yue Huang, Jingping Qu et al. • Molecules (2023)

The concurrent construction of 1,3-stereocenters remains a challenge. Herein, we report the development of stereoselective union of a point chiral center with allenyl axial chirality in 1,3-position by Pd-catalyzed asymmetric allenylic alky...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28072927

Surface-Modified Nanocellulose for Application in Biomedical Engineering and Nanomedicine: A Review

Tortorella S, Vetri Buratti V, Maturi M, Sambri L et al. • International Journal of Nanomedicine (2020)

Silvia Tortorella, Veronica Vetri Buratti, Mirko Maturi, Letizia Sambri, Mauro Comes Franchini, Erica Locatelli Department of Industrial Chemistry “Toso Montanari”, Alma Mater Studiorum – University of Bologna, Bologna 401...

DOAJ Open Access (DOAJ)

Characterization of low-nitrogen quantum diamond for pulsed magnetometry applications

Jiashen Tang, Jiashen Tang, Connor A. Roncaioli, Andrew M. Edmonds et al. • Frontiers in Quantum Science and Technology (2025)

Ensembles of nitrogen-vacancy (NV) centers in diamond are versatile quantum sensors with broad applications in the physical and life sciences. The concentration of neutral substitutional nitrogen ([Ns0]) strongly influences NV electronic sp...

DOAJ Open Access (DOAJ) DOI: 10.3389/frqst.2025.1701548

Synthesis of ultra‐high molecular weight core cross‐linked star (CCS) polymer using high molecular weight spherical nanoparticles and arm‐first method

Guangyao Liu, Yongqi Yang, Chao Zheng, Xiaoqun Cao • Nano Select (2022)

Abstract P (N,N‐Dimethylacrylamide) ‐b‐P (2‐methoxyethyl acrylate) (PDMA‐b‐PMEA) and Poly (poly (ethylene glycol) methyl ether methacrylate) ‐b‐P (2‐methoxyethyl acrylate) (PPEGMA‐b‐PMEA) di‐block copolymer nanoparticles are prepared by RAF...

DOAJ Open Access (DOAJ) DOI: 10.1002/nano.202100216

Developing an Interferogram-Based Module with Machine Learning for Maintaining Leveling of Glass Substrates

Syuan-Cheng Chang, Chung-Ping Chang, Yung-Cheng Wang, Chi-Chieh Chu • Machines (2023)

In this research, we propose a method that utilizes machine learning to maintain the parallelism of the resonant cavity in a Fabry–Perot interferometer designed specifically for glass substrates. Based on the optical principle and theory, w...

DOAJ Open Access (DOAJ) DOI: 10.3390/machines11060668

Controlled Plasmonic Coupling in Silver Nanoplate Dimers for Enhanced Plasmonic Sensing

Lucrezia Catanzaro, Marcello Condorelli, Mario Pulvirenti, Luisa D’urso et al. • Nanomaterials (2026)

Noble metal nanostructures provide versatile platforms for light manipulation through localized surface plasmon resonances (LSPRs). Among them, triangular silver nanoplates (AgNPTs) exhibit strong field-enhancement and spectral tunability, ...

DOAJ Open Access (DOAJ) DOI: 10.3390/nano16080486

Impact of prolonged obstructive sleep apnea syndrome disease course on retinal-choroidal microcirculation: a WF-SS-OCTA study

Chaomin Chen, Xinyi Chen, Lixia Qin, Mingming Zhao et al. • Photodiagnosis and Photodynamic Therapy (2026)

Purpose: This study used wide-field swept-source optical coherence tomography angiography (WF-SS-OCTA) to evaluate changes in macular vascular density in patients with obstructive sleep apnea syndrome (OSAS) at different stages of disease d...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.pdpdt.2026.105582