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Advances in microneedle-based drug delivery system for metabolic diseases: structural considerations, design strategies, and future perspectives

Yao Li, Qiu Chen, Tingting Wang, Zengkai Ji et al. • Journal of Nanobiotechnology (2025)

Abstract As the prevalence of metabolic diseases such as diabetes and obesity continue to rise, the search for more effective and convenient treatments has become a crucial issue in medical research. Microneedles (MNs), as an innovative dru...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03432-9

Computational Tools; Indispensable Armamentarium of Medical Biotechnology

Nutan, Swapnil Jain, K Shilpa, Akanksha Tomar et al. • Indian Journal of Science and Technology (2016)

Objective: Computational infrastructure of medical biotechnology provides insight into elements of genomics, proteomics for understanding diseases and biological systems in a more comprehensive and systematic way. The present study exclusiv...

OPENALEX cc-by DOI: https://doi.org/10.17485/ijst/2016/v9i32/100745

Calliphoridae Flies in Medical Biotechnology

A. Yu. Yakovlev, Anastasia A. Kruglikova, Sergey I. Chernysh • Entomological Review (2019)

Blow flies (Diptera, Calliphoridae) and their medical applications have attracted the attention of biologists and doctors for more than a century. The best known is the use of “surgical maggots” in the treatment of infected wounds and ulcer...

OPENALEX DOI: https://doi.org/10.1134/s0013873819030023

Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome

Antonio Musolino, Marco Roversi, Mariateresa Romaniello, Vittorio Scoppola et al. • Vaccine: X (2025)

Introduction: Pneumococcal vaccination has significantly decreased the burden of invasive pneumococcal disease in the general population, however studies on effectiveness in Down syndrome (DS) are heterogeneous. In this cross-sectional stud...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jvacx.2025.100744

Epstein–Barr Virus-Induced Metabolic Rearrangements in Human B-Cell Lymphomas

Pier P. Piccaluga, Pier P. Piccaluga, Pier P. Piccaluga, Alessandra Weber et al. • Frontiers in Microbiology (2018)

Tumor metabolism has been the object of several studies in the past, leading to the pivotal observation of a consistent shift toward aerobic glycolysis (so-called Warburg effect). More recently, several additional investigations proved that...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2018.01233

Deregulated miRNA clusters in ovarian cancer: Imperative implications in personalized medicine

Amoolya Kandettu, Divya Adiga, Vasudha Devi, Padmanaban S. Suresh et al. • Genes and Diseases (2022)

Ovarian cancer (OC) is one of the most common and fatal types of gynecological cancer. OC is usually detected at the advanced stages of the disease, making it highly lethal. miRNAs are single-stranded, small non-coding RNAs with an approxim...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.gendis.2021.12.026

Current Evidence on Gene-Based and Epigenetic Therapeutic, Diagnostic, and Prognostic Strategies in Epithelial-Derived Carcinomas: A Scoping Review

Joshua George Thomas, Mohammed Ayyub, Lovely M. Annamma, Prathibha Prasad et al. • Biomedicines (2026)

Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progressio...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines14102234

Pharmacological significance of MitoQ in ameliorating mitochondria-related diseases

Lateef Adegboyega Sulaimon, Lukman Olalekan Afolabi, Rahmat Adetutu Adisa, Akinrinade George Ayankojo et al. • Advances in Redox Research (2022)

The Mitochondria is a critical sub-cellular organelle that plays an integral part in a normal cellular process. Besides ATP production, the mitochondria participate in various key cellular processes such as cell signaling, epigenetic regula...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.arres.2022.100037

International Journal of Medical Biotechnology & Genetics

Saket RD, Kol S, Tripathi AK, Singh SP et al. • International Journal of Medical Biotechnology & Genetics (2022)

International Journal of Medical Biotechnology & Genetics (IJMBG) ISSN: 2379-1020 is a comprehensive, peer reviewed journal devoted to Medical Biotechnology and Genetics. publishes original research, latest developments, review papers, scie...

OPENALEX cc-by DOI: https://doi.org/10.19070/2379-1020

Plant Virus–Derived Vectors: Applications in Agricultural and Medical Biotechnology

Peter E. Abrahamian, Rosemarie W. Hammond, John Hammond • Annual Review of Virology (2020)

Major advances in our understanding of plant viral genome expression strategies and the interaction of a virus with its host for replication and movement, induction of disease, and resistance responses have been made through the generation ...

OPENALEX DOI: https://doi.org/10.1146/annurev-virology-010720-054958

Developments in Exploring Fungal Secondary Metabolites as Antiviral Compounds and Advances in HIV-1 Inhibitor Screening Assays

Bruce Nzimande, John P. Makhwitine, Nompumelelo P. Mkhwanazi, Sizwe I. Ndlovu • Viruses (2023)

The emergence of drug-resistant Human Immunodeficiency Virus-1 strains against anti-HIV therapies in the clinical pipeline, and the persistence of HIV in cellular reservoirs remains a significant concern. Therefore, there is a continuous ne...

DOAJ Open Access (DOAJ) DOI: 10.3390/v15051039

A Novel Prognostic Scoring Model for Myelodysplastic Syndrome Patients With SF3B1 Mutation

Liya Ma, Bin Liang, Huixian Hu, Wenli Yang et al. • Frontiers in Oncology (2022)

The outcomes of myelodysplastic syndrome (MDS) patients with SF3B1 mutation, despite identified as a favorable prognostic biomarker, are variable. To comprehend the heterogeneity in clinical characteristics and outcomes, we reviewed 140 MDS...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.905490

Accomplishments in genome‐scale in silico modeling for industrial and medical biotechnology

Caroline B. Milne, Pan‐Jun Kim, James A. Eddy, Nathan D. Price • Biotechnology Journal (2009)

Driven by advancements in high-throughput biological technologies and the growing number of sequenced genomes, the construction of in silico models at the genome scale has provided powerful tools to investigate a vast array of biological sy...

OPENALEX Open Access DOI: https://doi.org/10.1002/biot.200900234 PMC: 3160784

Medical Biotechnology

Dylan R. Pillai • Clinical Infectious Diseases (2014)

Both the diagnosis and treatment of human disease have undergone radical changes since the seminal discoveries of molecular biology, magnetic resonance imaging, mass spectrometry, and vaccine development, to name but a few. Glick and collea...

OPENALEX DOI: https://doi.org/10.1093/cid/ciu510