Academic Articles & Research Papers

Deep Learning and Its Applications in Biomedicine

Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data, such as medical images, electroencephalography, genomic and protein sequences. Learning from these data facilitat...

Comparing deep learning and pathologist quantification of cell-level PD-L1 expression in non-small cell lung cancer whole-slide images

Abstract Programmed death-ligand 1 (PD-L1) expression is currently used in the clinic to assess eligibility for immune-checkpoint inhibitors via the tumor proportion score (TPS), but its efficacy is limited by high interobserver variability...

A novel network-level fused deep learning architecture with shallow neural network classifier for gastrointestinal cancer classification from wireless capsule endoscopy images

Abstract Deep learning has significantly contributed to medical imaging and computer-aided diagnosis (CAD), providing accurate disease classification and diagnosis. However, challenges such as inter- and intra-class similarities, class imba...

IoT-RiceMobileNet: An improved lightweight MobileNetV2 Model for real-time multi-class rice disease detection using IoT.

Early and real-time detection of rice leaf diseases (RLD) poses a significant challenge for farmers, especially in rural regions with limited access to advanced technology. Conventional deep learning models often require substantial computa...

A deep learning model for the localization and extraction of brain tumors from MR images using YOLOv7 and grab cut algorithm

IntroductionBrain tumors are a common disease that affects millions of people worldwide. Considering the severity of brain tumors (BT), it is important to diagnose the disease in its early stages. With advancements in the diagnostic process...

Deep Learning in Medical Image Analysis

This review covers computer-assisted analysis of images in the field of medical imaging. Recent advances in machine learning, especially with regard to deep learning, are helping to identify, classify, and quantify patterns in medical image...

Advancements in 7T magnetic resonance diffusion imaging: Technological innovations and applications in neuroimaging

Abstract The development of 7‐Tesla (7T) magnetic resonance imaging systems has opened new avenues for exploring the advantages of diffusion imaging at higher field strengths, especially in neuroscience research. This review investigates wh...

A deep-learning system to classify lung X-ray images into normal/pneumonia class

An explainable machine learning framework for cross-dataset chronic kidney disease risk prediction using hybrid data balancing.

Integrating Multisource Target Evidence with Machine-Learning Potency Prediction for Alzheimer’s Disease Drug Discovery.

Diffusion tensor imaging for rehabilitation and prevention of lumbar degenerative diseases: a narrative review.

A machine learning and clustering-based approach for county-level COVID-19 analysis.

COVID-19 is a global pandemic threatening the lives and livelihood of millions of people across the world. Due to its novelty and quick spread, scientists have had difficulty in creating accurate forecasts for this disease. In part, this is...

A Cardiovascular Disease Prediction Model Based on Routine Physical Examination Indicators Using Machine Learning Methods: A Cohort Study

BackgroundCardiovascular diseases (CVD) are currently the leading cause of premature death worldwide. Model-based early detection of high-risk populations for CVD is the key to CVD prevention. Thus, this research aimed to use machine learni...

Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease

Abstract Background Astrocytes and microglia react to Aβ plaques, neurofibrillary tangles, and neurodegeneration in the Alzheimer’s disease (AD) brain. Single-nuclei and single-cell RNA-seq have revealed multiple states or subpopulations of...

Identification and Predictors for Cardiovascular Disease Risk Equivalents Among Adults With Diabetes.

On the use of aspect-based sentiment analysis of Twitter data to explore the experiences of African Americans during COVID-19

Abstract According to data from the U.S. Center for Disease Control and Prevention, as of June 2020, a significant number of African Americans had been infected with the coronavirus disease, experiencing disproportionately higher death rate...

Targeting the alpha-synuclein protein to treat Parkinson's disease using novel inhibitors identified using an integrated computational drug development approaches.

CViewer: a Java-based statistical framework for integration of shotgun metagenomics with other omics datasets

Abstract Background Shotgun metagenomics for microbial community survey recovers enormous amount of information for microbial genomes that include their abundances, taxonomic, and phylogenetic information, as well as their genomic makeup, t...

Hybrid feature optimized CNN for rice crop disease prediction

Abstract The agricultural industry significantly relies on autonomous systems for detecting and analyzing rice diseases to minimize financial and resource losses, reduce yield reductions, improve processing efficiency, and ensure healthy cr...

Passive early screening for Alzheimer's disease and related dementias using EHR comorbidity patterns.