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Academic Articles & Research Papers
Showing 20 of 402 academic articles
Otavio A. F. S. Da Silva, Samuel I. D. S. Pereira, Alper Mert, Débora R. de Aguiar et al. • Frontiers in Psychiatry
(2026)
IntroductionDepressive disorders are a prevalent psychiatric condition; major depressive disorder (MDD) specifically affects approximately 5.7% of adults worldwide and is associated with high levels of disability and disease burden. Althoug...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fpsyt.2026.1899231
Laura Navarro, Laura Navarro, Laura Navarro, Nour El Zahraa Mallah et al. • Frontiers in Integrative Neuroscience
(2026)
Brain damage (BD) caused by stroke, traumatic brain injury (TBI), or neurodegenerative conditions often results in persistent cognitive, motor, and emotional impairments. Music-based interventions (MI) have been explored as adjunctive rehab...
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Open Access (DOAJ)
DOI: 10.3389/fnint.2026.1720473
Dipsikha Biswas, Logan Slade, Luke Duffley, Neil Mueller et al. • Cell Death Discovery
(2021)
Proposed mechanism. A Doxorubicin (DOX) targets the BCAA catabolic pathway in TNBCs, by downregulating BCKDK and augmenting clearance of intracellular BCKAs. B Genetic or pharmacological (high BT2 concentration) inhibition of BCKDK results ...
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Open Access (DOAJ)
DOI: 10.1038/s41420-021-00602-0
Alexandra Kühnlein, Simon A Lanzmich, Dieter Braun • eLife
(2021)
Can replication and translation emerge in a single mechanism via self-assembly? The key molecule, transfer RNA (tRNA), is one of the most ancient molecules and contains the genetic code. Our experiments show how a pool of oligonucleotides, ...
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Open Access (DOAJ)
DOI: 10.7554/eLife.63431
Adam H. Tencer, Jiuyang Liu, Jing Zhu, Nathaniel T. Burkholder et al. • Scientific Reports
(2022)
Abstract The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protein. Here, we show that the ZZ domain of HERC2 (HERC2ZZ) recognizes a mimetic of the Nt-R cargo ...
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Open Access (DOAJ)
DOI: 10.1038/s41598-022-10119-w
Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova et al. • Communications Biology
(2022)
Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms....
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Open Access (DOAJ)
DOI: 10.1038/s42003-022-03753-7
Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang et al. • Journal of Translational Medicine
(2024)
Abstract Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-deri...
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Open Access (DOAJ)
DOI: 10.1186/s12967-024-05257-w
Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports
(2025)
Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...
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Open Access (DOAJ)
DOI: 10.1038/s41598-025-32406-y
Alexis Laurent, Corinne Scaletta, Philippe Abdel-Sayed, Murielle Michetti et al. • Biomedicines
(2021)
Cultured fibroblast progenitor cells (FPC) have been studied in Swiss translational regenerative medicine for over two decades, wherein clinical experience was gathered for safely managing burns and refractory cutaneous ulcers. Inherent FPC...
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Open Access (DOAJ)
DOI: 10.3390/biomedicines9081072
Baigang Mi, Hao Zhan • IEEE Access
(2019)
By considering the exclusion characteristics of foreign objects in a new intake system with a bypass duct for turboprop engines, two kinds of common rigid foreign objects, the grains, and metal pieces, are modeled based on airworthiness sta...
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Open Access (DOAJ)
DOI: 10.1109/ACCESS.2019.2916551
Michal Elkind, Itamar Cohen, David Blackman, Talia Meir et al. • Scientific Reports
(2023)
Abstract Intense laser fields interact very differently with micrometric rough surfaces than with flat objects. The interaction features high laser energy absorption and increased emission of MeV electrons, ions, and of hard x-rays. In this...
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Open Access (DOAJ)
DOI: 10.1038/s41598-023-48866-z
Yan Dora Zhang, Amber N. Hurson, Haoyu Zhang, Parichoy Pal Choudhury et al. • Nature Communications
(2020)
In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and ...
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Open Access (DOAJ)
DOI: 10.1038/s41467-020-16483-3
Olga Vishnyakova, Joosung Min, Stephen Leach, Xiaowei Song et al. • Communications Medicine
(2026)
Abstract Background Chronological age does not capture individual health or resilience. Advances in metabolomics have enabled development of molecular aging biomarkers that capture deviations between biological and chronological age, highli...
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Open Access (DOAJ)
DOI: 10.1038/s43856-026-01375-2
Walla Malkawi, Areeb Lutfi, Maaz Khan Afghan, Lamisha Mashiyat Shah et al. • Frontiers in Oncology
(2023)
ObjectiveMost of the work in terms of liquid biopsies in patients with solid tumors is focused on circulating tumor DNA (ctDNA). Our aim was to evaluate the feasibility of using circulating tumor cells (CTCs) in peripheral blood samples fro...
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Open Access (DOAJ)
DOI: 10.3389/fonc.2023.1305181
Wendy A. McDougald, Richard Collins, Mark Green, Adriana A. S. Tavares • Frontiers in Physics
(2017)
Obtaining accurate quantitative measurements in preclinical Positron Emission Tomography/Computed Tomography (PET/CT) imaging is of paramount importance in biomedical research and helps supporting efficient translation of preclinical result...
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Open Access (DOAJ)
DOI: 10.3389/fphy.2017.00050
Man Luo, Man Luo, Man Luo, Jiang Zhu et al. • Frontiers in Pharmacology
(2025)
BackgroundDrug repurposing has emerged as a promising approach for discovering novel anticancer therapeutics. In this study, we systematically investigated the antitumor potential of fedratinib, a JAK2 inhibitor approved for myelofibrosis, ...
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Open Access (DOAJ)
DOI: 10.3389/fphar.2025.1689663
Giovanna Di Pasquale, Antonino Pollicino • Micromachines
(2026)
Molecularly imprinted polymers (MIPs) are synthetic receptors with cavities shaped around a template, combining antibody-like selectivity with chemical, thermal, and mechanical robustness; low cost; and reusability. This Review examines rec...
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Open Access (DOAJ)
DOI: 10.3390/mi17091037
Patricia Piechowski, Gina Claxton, Nicola Spencer, Elizabeth Vasile et al. • Journal of Clinical and Translational Science
(2022)
OBJECTIVES/GOALS: Since 2013, managers of community engagement (CE) programs across the Clinical and Translational Science Award (CTSA) consortium funded by the National Center for Advancing Translational Sciences (NCATS) have convened mont...
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Open Access (DOAJ)
DOI: 10.1017/cts.2022.67
Krina Parmar, Pauline Dufour, Emma Texier, Cécile Carrétéro et al. • Nature Communications
(2025)
Abstract The nature of lead zirconate, the historical antiferroelectric material, has recently been challenged. In PbZrO3 epitaxial films, thickness reduction engenders competition among antiferroelectric, ferrielectric and ferroelectric ph...
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Open Access (DOAJ)
DOI: 10.1038/s41467-025-61867-y
Miguel González-Lozano, José Alberto Cano-Buendía • Veterinary World
(2025)
Background and Aim: Chitosan-based DNA nanoparticles have emerged as a promising next-generation platform for veterinary vaccines, addressing several limitations of conventional attenuated, inactivated, and recombinant formulations. Chitosa...
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Open Access (DOAJ)
DOI: 10.14202/vetworld.2025.3826-3838