Home »
Academic Articles & Research Papers
Showing 20 of 172 academic articles
Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer
(2024)
Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/jitc-2023-008450
Sophia Daum, Lilith Decristoforo, Mira Mousa, Stefan Salcher et al. • Molecular Cancer
(2025)
Abstract The dynamic interactions between tumor endothelial cells (TECs) and the immune microenvironment play a critical role in the progression of non-small cell lung cancer (NSCLC). In general, endothelial cells exhibit diverse immunomodu...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12943-024-02221-6
Kun Huang, Shuoshuo Hu, Yilin Zhou, Qingqing Cao et al. • Environmental Chemistry and Ecotoxicology
(2025)
Introduction: Adult exposure to endocrine-disrupting chemicals (EDCs) may reduce muscle mass and strength; however, few studies considered EDC mixtures and their potential mechanisms. Objectives: We aimed to explore associations of EDC mixt...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.enceco.2025.08.019
Alessandro L. Gallina, Urszula Rykaczewska, Robert C. Wirka, Robert C. Wirka et al. • Frontiers in Cardiovascular Medicine
(2021)
Objectives and Aims: Vascular smooth muscle cells (VSMCs) are key constituents of both normal arteries and atherosclerotic plaques. They have an ability to adapt to changes in the local environment by undergoing phenotypic modulation. An im...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fcvm.2021.655869
Rebecca I. Clark, Anna Salazar, Ryuichi Yamada, Sorel Fitz-Gibbon et al. • Cell Reports
(2015)
Alterations in the composition of the intestinal microbiota have been correlated with aging and measures of frailty in the elderly. However, the relationships between microbial dynamics, age-related changes in intestinal physiology, and org...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.celrep.2015.08.004
Ruifeng Xiao, Cong Shen, Wen Shen, Xunan Wu et al. • Current Issues in Molecular Biology
(2025)
Fyn is widely involved in diverse cellular physiological processes, including cell growth and survival, and has been implicated in the regulation of energy metabolism and the pathogenesis of diabetes mellitus through multiple pathways. Fyn ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cimb47080623
Leandro José de Assis, Lilian Pereira Silva, Ozgur Bayram, Paul Dowling et al. • mBio
(2021)
In filamentous fungi, the transcription factor CreA controls carbohydrate metabolism through the regulation of genes encoding enzymes required for the use of alternative carbon sources. In this work, phosphorylation sites were identified on...
DOAJ
Open Access (DOAJ)
DOI: 10.1128/mBio.03146-20
Kushal J. Rohilla, Keith T. Gagnon • Acta Neuropathologica Communications
(2017)
Abstract Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurolog...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s40478-017-0468-y
Haiyan Yang, Ming Sun, Shuangji Lin, Yanhong Guo et al. • PLoS ONE
(2017)
Soil salinization is becoming a limitation to the utilization of ornamental plants worldwide. Crossostephium chinensis (Linnaeus) Makino is often cultivated along the southeast coast of China for its desirable ornamental qualities and high ...
DOAJ
Open Access (DOAJ)
DOI: 10.1371/journal.pone.0187124
Amit Khatri, Vineet Choudhary • STAR Protocols
(2023)
Summary: The mechanisms underlying lipid droplet (LD) biogenesis in the endoplasmic reticulum are not completely understood. Here, we present a protocol for inducing de novo LDs containing either triacylglycerol (TAG) or sterol esters (SE) ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.xpro.2023.102732
Holly Pollard-Wright • Frontiers in Human Neuroscience
(2026)
Conscious processing is associated with coordinated interactions among distributed neural systems, yet the biological constraints that enable and sustain large-scale neural integration remain incompletely understood. Contemporary theories e...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnhum.2026.1966072
T. Yu. Poniatowskaya • Journal of Education, Health and Sport
(2015)
Poniatowskaya T. Yu. Effect of angiotensin-converting enzyme gene polymorphism at the results of losartan use in the patients with type 2 diabetes mellitus. Journal of Education, Health and Sport. 2015;5(3):55-61. ISSN 2391-8306. DOI: 10.52...
DOAJ
Open Access (DOAJ)
Yun Chen, Yun Chen, Kangrong Wang, Kangrong Wang et al. • Frontiers in Pharmacology
(2025)
BackgroundHydrogen gas (H2), which is the lightest and diffusible gas molecule, has strong abilities to alleviate excessive oxidative stress, inflammation, and apoptosis. Inhalation of H2 is beneficial for preventing the damage of the lung,...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fphar.2025.1575106
Edoardo Pozio • Food and Waterborne Parasitology
(2022)
The main reservoir hosts of nematodes of the genus Trichinella are wild carnivores, although most human infections are caused by the consumption of pork. This group of zoonotic parasites completes the entire natural life cycle within the ho...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.fawpar.2022.e00154
Susheel Kumar Nethi, Venugopal Gunda, Nagabhishek Sirpu Natesh, Brianna M. White et al. • iScience
(2025)
Summary: Pancreatic cancer (PC) exhibits profound metabolic adaptations that support tumor progression, survival, and therapy resistance. Hypoxia-inducible factor-1α (HIF-1α) is a key regulator of these processes, promoting metabolic reprog...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.isci.2025.114088
Marjo J. den Broeder, Jarle Ballangby, Leonie M. Kamminga, Peter Aleström et al. • Epigenetics & Chromatin
(2020)
Abstract Background Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This susceptibility may in part be caused by changes to the epigenetic landscape which conseq...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13072-020-0329-y
Chinmay Saha, Sayantan Laha, Raghunath Chatterjee, Nitai P. Bhattacharyya • Non-Coding RNA
(2021)
Altered expression of protein coding gene (PCG) and long non-coding RNA (lncRNA) have been identified in SARS-CoV-2 infected cells and tissues from COVID-19 patients. The functional role and mechanism (s) of transcriptional regulation of de...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/ncrna7040074
Magdalena Sevilla-González, Maria Fernanda Garibay-Gutiérrez, Arsenio Vargas-Vázquez, Andrea Celeste Medina-García et al. • Current Developments in Nutrition
(2024)
Background: A risk haplotype in SLC16A11 characterized by alterations in fatty acid metabolism emerged as a genetic risk factor associated with increased susceptibility to type 2 diabetes (T2D) in Mexican population. Its role on treatment r...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.cdnut.2024.104444
Nanting Huang, Xiaoyu Li, Xin Yang, Li Xie et al. • Sensors
(2026)
The pathological mechanism of autism spectrum disorder (ASD) exhibits dual heterogeneity: abnormal local energy metabolism and brain-wide high-order topological failure. To synergistically characterize these complex signals captured by adva...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/s26133997
Yohann Le Govic, Yohann Le Govic, Nicolas Papon, Solène Le Gal et al. • Frontiers in Microbiology
(2018)
The ubiquitous mold Scedosporium apiospermum is increasingly recognized as an emerging pathogen, especially among patients with underlying disorders such as immunodeficiency or cystic fibrosis (CF). Indeed, it ranks the second among the fil...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmicb.2018.00827