Academic Articles & Research Papers

Quantum-Resistant Security Technologies for Resource-Constrained Edge Devices: Challenges and Lightweight Countermeasures

With the rapid advancement of quantum computing technology, IoT edge devices widely deployed in industrial settings are facing severe threats to their quantum-resistant security. This work focuses on the challenges of adapting Quantum Key D...

Mesh partitioning for distributed systems

Distributed systems, which consist of a collection of high performance systems interconnected via high performance networks (e.g. ATM), are becoming feasible platforms for execution of large-scale, complex problems. We address various issue...

Distributed Systems

This chapter addresses the issues involved in distributed databases, where a database is stored on more than one computer. It provides an introduction to parallel and distributed computing as a foundation for the better understanding of clo...

On the way to a distributed systems calculus

Network calculus is a min-plus system theory which facilitates the efficient derivation of performance bounds for networks of queues. It has successfully been applied to provide end-to-end quality of service guarantees for integrated and di...

Distributed Systems

The origins of big data technologies come from database systems and distributed systems as well as data mining and machine learning algorithms that can process these vast amounts of data to extract the necessary knowledge. This chapter addr...

The LOCUS Distributed System Architecture

LOCUS, a distributed version of the popular operating system Unix, provides an excellent solution. It makes a collection of computers, whether they are workstations or mainframes, as easy to use as a single computer by providing a set of su...

Geoscientists’ Perspectives on Cyberinfrastructure Needs: A Collection of User Scenarios

Cyberinfrastructure (CI) is a standard tool in the geosciences, but the creation of successful CI remains difficult, and expensive projects can have significant consequences for scientific communities if they do not result in success. In th...

A Scalable Real-Time SDN-Based MQTT Framework for Industrial Applications

The increasing prominence of concepts such as Smart Production and Industrial Internet of Things (IIoT) within the context of Industry 4.0 has introduced a new set of requirements for the engineering of industrial systems, including support...

Software engineering and middleware

The construction of a large class of distributed systems can be simplified by leveraging middleware, which is layered between network operating systems and application components. Middleware resolves heterogeneity and facilitates communicat...

A millifluidic study of cell-to-cell heterogeneity in growth-rate and cell-division capability in populations of isogenic cells of Chlamydomonas reinhardtii.

To address possible cell-to-cell heterogeneity in growth dynamics of isogenic cell populations of Chlamydomonas reinhardtii, we developed a millifluidic drop-based device that not only allows the analysis of populations grown from single ce...

TDP-43-related cryptic splicing reflects pathological heterogeneity in amyotrophic lateral sclerosis.

Unrevealing the dual role of paired box and sex determining region Y related high mobility group box in glioblastoma

Abstract This narrative review summarises glioblastoma (GBM), a very frequent invasive kind of brain tumour in the elderly that is extremely aggressive, resistant to treatment, and has a bad prognosis because of its substantial genetic and ...

Molecular Biology of Neuroblastoma

UNLABELLED: PURPOSE AND RESULTS: Neuroblastoma, the most common solid extracranial neoplasm in children, is remarkable for its clinical heterogeneity. Complex patterns of genetic abnormalities interact to determine the clinical phenotype. T...

Pore-Throat-Adaptive Transport and Flow-Redistribution Mechanisms of Deformable Hydrogel Particles in Tight Reservoirs of the Ordos Basin

Tight reservoirs commonly exhibit strong pore-throat confinement and flow heterogeneity, which cause injected water to preferentially migrate through connected high-conductivity pathways while a large fraction of movable fluids remains unde...

Feddsg: backdoor defense via semantic filter and geometric constraint in federated learning

Abstract Backdoor attacks pose a serious threat to Internet-of-Things (IoT) federated learning. In IoT deployments, pronounced non-independent and identically distributed (non-IID) data heterogeneity causes benign client updates to exhibit ...

Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors

Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of hematologic malignancies, achieving remarkable clinical success with FDA-approved therapies targeting CD19 and BCMA. However, the extension of these successe...

Cardiovascular and metabolic outcomes associated with moderate-to-severe atopic dermatitis: A systematic review and meta-analysis

Background: Chronic systemic inflammation in individuals with moderate-to-severe atopic dermatitis (AD) potentially predisposes them to metabolic and cardiovascular diseases. Nevertheless, evidence with regard to such association is limited...

Worldwide productivity and research trend of publications concerning extracellular vesicles role in fibrosis: A bibliometric study from 2013 to 2022

Background: Fibrosis is a heavy burden on the global healthcare system. Recently, an increasing number of studies have demonstrated that Extracellular vesicles play an important role in intercellular communication under both physiological a...

Evidence for Enrichment of Niobium-92 in the Outer Protosolar Disk

The short-lived radionuclide, niobium-92 ( ^92 Nb), has been used to estimate the site of nucleosynthesis for p- nuclei and the timing of planetary differentiation, assuming that it was uniformly distributed in the early solar system. Here,...

PRIMUS: Comprehensive proteomics of mouse intervertebral discs that inform novel biology and relevance to human disease modelling

Mice are commonly used to study intervertebral disc (IVD) biology and related diseases such as IVD degeneration. Discs from both the lumbar and tail regions are used. However, little is known about compartmental characteristics in the diffe...