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Showing 20 of 335 academic articles

The Utilization of Plant-Material-Loaded Vesicular Drug Delivery Systems in the Management of Pulmonary Diseases

Bongani Sannyboy Lukhele, Kokoette Bassey, Bwalya Angel Witika • Current Issues in Molecular Biology (2023)

Medicinal plants have been utilized to treat a variety of conditions on account of the bioactive properties that they contain. Most bioactive constituents from plants are of limited effectiveness, due to poor solubility, limited permeabilit...

DOAJ Open Access (DOAJ) DOI: 10.3390/cimb45120624

Efficacy, safety, and quality of life 4 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A in the phase 3 GENEr8-1 trial

Andrew D. Leavitt, Johnny Mahlangu, Priyanka Raheja, Emily Symington et al. • Research and Practice in Thrombosis and Haemostasis (2024)

Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rpth.2024.102615

Standardized Extract of Atractylodis Rhizoma Alba and Fructus Schisandrae Ameliorates Coughing and Increases Expectoration of Phlegm

Hee-Sung Chae, Sun Young Kim, Pisey Pel, Jungmoo Huh et al. • Molecules (2020)

Cough and phlegm frequently occur in respiratory diseases like upper respiratory tract infections, acute bronchitis, and chronic obstructive pulmonary diseases. To relieve these symptoms and diseases, various ingredients are being used desp...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules25133064

Molecular Dynamics and In Vitro Studies Elucidating the Tunable Features of Reconfigurable Nanodiscs for Guiding the Optimal Design of Curcumin Formulation

Yongxiao Li, Wanting Xu, Xinpei Wang, Ruizhi Lai et al. • Bioengineering (2024)

In this study, we advance our exploration of Apolipoprotein A-I (apoA-I) peptide analogs (APAs) for their application in nanodisc (ND) assembly, focusing on the dynamic conformational characteristics and the potential for drug delivery. We ...

DOAJ Open Access (DOAJ) DOI: 10.3390/bioengineering11030245

Effects of Dietary Supplementation with Moringa oleifera on HIV Viral Load in Adults Receiving Standard Care

Phyllis Waruguru, Dasel Mulwa, Michael Okoth, Wesley Bor • Journal of Food Innovation, Nutrition, and Environmental Sciences (2025)

Background: Antiretroviral therapy (ART) effectively suppresses HIV viral load. However, people living with HIV (PLWH) fail to achieve optimal viral suppression and especially in resource limited settings. Nutritional supplements such as Mo...

DOAJ Open Access (DOAJ) DOI: 10.70851/ynxgrq90

Efficacy of heel lifts versus calf muscle eccentric exercise for mid-portion Achilles tendinopathy (the HEALTHY trial): study protocol for a randomised trial

Chantel L. Rabusin, Hylton B. Menz, Jodie A. McClelland, Angela M. Evans et al. • Journal of Foot and Ankle Research (2019)

Abstract Background Mid-portion Achilles tendinopathy is a common musculoskeletal condition characterised by degeneration of the Achilles tendon, which causes pain and disability. Multiple non-surgical treatments have been advocated for thi...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13047-019-0325-2

Linear Potentiometer Sensor-Based of Athlete Flexibility Measurement Tool

Dzihan Khilmi Ayu Firdausi, Muhammad Eka Mardyansyah Simbolon, Indra Dwisaputra, Catur Pebriandani • Jurnal Teknik Elektro Indonesia (2024)

This study aims to develop a novel "sit and reach test" flexometer device utilizing a linear potentiometer sensor to quantitatively evaluate an individual's body flexibility. The innovation in this research lies in the utilization of electr...

DOAJ Open Access (DOAJ) DOI: 10.24036/jtein.v5i1.541

The structural diversity of ibuprofen sustained-release pellets on the same goal of bioequivalence consistency

Zeying Cao, Ningyun Sun, Hongyu Sun, Jun Liu et al. • Materials & Design (2022)

The consistency evaluation, which is largely unexplored is crucial in regulating the quality and efficacy of generic drugs. In this report, after generic ibuprofen (IBU) sustained-release pellets were developed and validated as bioequivalen...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.matdes.2022.110583

Optimization of cationic nanoparticles stabilized by poloxamer 188: A potential approach for improving the biological activity of Aloe perryi

Tahany Saleh Aldayel, Mohamed M. Badran, Abdullah H. Alomrani, Nora A. AlFaris et al. • Heliyon (2023)

Aloe perryi (AP) has gained considerable interest as a medicinal herb in various biological applications due to its rich phytochemical composition. However, the therapeutic benefits of AP could be potentiated by utilizing nanotechnology. Mo...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2023.e22691

THERAPEUTIC EFFECT OF PACLITAXEL LOADED ON GOLD NANOPARTICLES IN TREATMENT OF INDUCED ORAL SQUAMOUS CELL CARCINOMA

Fatma H. El-Didi, Marwa M. Essawy, Sagy L. Asar, Sahar M. El-Sheikh et al. • Alexandria Dental Journal (2019)

INTRODUCTION: Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide with high mortality rate. Conventional treatment strategies have improved but remain far from optimal. Cancer research is focused on improving cance...

DOAJ Open Access (DOAJ) DOI: 10.21608/adjalexu.2019.57569

Gold nanoparticles synthesized from Bacopa monneri plant extract: Bovine serum albumin protein interactions and antibacterial effectiveness

Pranita Rananaware, H. Swetha, Varsha Brahmkhatri • Next Nanotechnology (2025)

Gold nanoparticles (AuNPs) are widely used in various scientific and technological domains, particularly biomedicine due to their superior biocompatibility. This study focuses on the synthesis of biogenic gold nanoparticles (B-Au) and chemo...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nxnano.2025.100305

The Effects of Alkaline Pretreatment on Agricultural Biomasses (Corn Cob and Sweet Sorghum Bagasse) and Their Hydrolysis by a Termite-Derived Enzyme Cocktail

Mpho. S. Mafa, Samkelo Malgas, Abhishek Bhattacharya, Konanani Rashamuse et al. • Agronomy (2020)

Sweet sorghum bagasse (SSB) and corncob (CC) have been identified as promising feedstocks for the production of second-generation biofuels and other value-added chemicals. In this study, lime (Ca(OH)2) and NaOH pretreatment efficacy for dec...

DOAJ Open Access (DOAJ) DOI: 10.3390/agronomy10081211

Bacteriophage: A Useful Tool for Studying Gut Bacteria Function of Housefly Larvae, Musca domestica

Xinyu Zhang, Shumin Wang, Ting Li, Qian Zhang et al. • Microbiology Spectrum (2021)

ABSTRACT Beneficial symbiotic bacteria have positive effects on some insects’ (such as mosquitoes, cockroaches, and flies) biological activities. However, the effects of a lack of one specific symbiotic bacterium on the life activities of s...

DOAJ Open Access (DOAJ) DOI: 10.1128/Spectrum.00599-21

Application of TyG index and carotid ultrasound parameters in the prediction of ischemic stroke

Huimin Guo, Huimin Guo, Sen Wang, Haizheng Wang et al. • Frontiers in Endocrinology (2025)

ObjectiveThe triglyceride - glucose (TyG) index has been confirmed as an independent risk factor for ischemic stroke (IS) in numerous studies. In terms of the role of carotid ultrasound in the risk assessment of IS, the focus has shifted fr...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2025.1481676

Was health skepticism accounted for in communication about the COVID-19 vaccine? A content analysis of federally-sponsored public service announcements about the vaccine to protect against COVID-19 in the United States

Margaret E. Tait, Erika Franklin Fowler, Sarah E. Gollust • Preventive Medicine Reports (2025)

Objective: To examine the content of public service announcements (PSAs) sponsored by the United States federal government to promote the COVID-19 vaccine and reveal if PSAs included content that countered health skepticism. Methods: A cont...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.pmedr.2025.103193

A study on high-shear and low-pressure grinding with body-armour-like abrasive tool (BAAT) for Inconel 718 superalloys

Yebing Tian, Chengjin Tian, Sohini Chowdhury, Jinguo Han et al. • Journal of Materials Research and Technology (2023)

A novel body-armour-like abrasive tool (BAAT) was developed for the high-shear and low-pressure grinding of super alloys with an aim to reduce the ratio of normal force to tangential force. A composite process model was developed based on f...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jmrt.2023.04.205

Relationship between Pb relative bioavailability and bioaccessibility in phosphate amended soil: Uncertainty associated with predicting Pb immobilization efficacy using in vitro assays

Farzana Kastury, Silvia Placitu, John Boland, Ranju R. Karna et al. • Environment International (2019)

In this study, an in vitro in vivo correlation (IVIVC) between Pb in vitro bioaccessibility (IVBA) and relative bioavailability (RBA) was explored to determine whether the efficacy of Pb immobilization in phosphate amended soils could be pr...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.envint.2019.104967

Investigating the efficacy of the Egyptian Data Protection Law on Media Freedom: Journalists’ perceptions

Miral-Sabry AlAshry • Communication & Society (Formerly Comunicación y Sociedad) (2022)

The purpose of this study is to investigate the effectiveness of the Egyptian Personal Data Protection Law No. 151 for 2020, as well as its implications for journalistic practice. More specifically, the focal point of this study was to expl...

DOAJ Open Access (DOAJ) DOI: 10.15581/003.35.1.101-118

The combined effects of goal attributes, motivational beliefs, creativity and grit on self-regulation in online ill-structured problem solving: a fsQCA approach

Huanhuan Wang, Shaofeng Wang, Ahmed Tlili, Mengti Li et al. • BMC Psychology (2025)

Abstract Self-regulated learning (SRL) has been regarded as one of the indispensable factors affecting students’ academic success in online learning environments. However, the current understanding of the mechanism/causes of SRL in online i...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40359-024-02317-0