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CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy

Xinyue Gao, Feichang Liu, Bo Zhang, Tianyi Ren et al. • Cell Death and Disease (2025)

Abstract Cell division cycle 25 (CDC25) phosphatases serve as crucial regulators of cell cycle phase transitions and essential components of the checkpoint machinery involved in DNA damage response. Emerging evidence indicates the oncogenic...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41419-025-07598-w

International Journal of Medical Biotechnology & Genetics

Saket RD, Kol S, Tripathi AK, Singh SP et al. • International Journal of Medical Biotechnology & Genetics (2022)

International Journal of Medical Biotechnology & Genetics (IJMBG) ISSN: 2379-1020 is a comprehensive, peer reviewed journal devoted to Medical Biotechnology and Genetics. publishes original research, latest developments, review papers, scie...

OPENALEX cc-by DOI: https://doi.org/10.19070/2379-1020

Extramedullary plasmacytoma of the oral cavity metastasising to both kidneys in a dog

Kyung Ho Park, Tae‐Un Kim, Hyun‐Woo Park, Seoung‐Woo Lee et al. • Veterinary Medicine and Science (2023)

Abstract Background Most extramedullary plasmacytomas (EMPs) aresolitary and located in the head and neck region. They may also occur in the visceral parts of the body. Objectives Here, we report a case of oral EMP followed by neoplastic pl...

DOAJ Open Access (DOAJ) DOI: 10.1002/vms3.1086

A Novel Prognostic Scoring Model for Myelodysplastic Syndrome Patients With SF3B1 Mutation

Liya Ma, Bin Liang, Huixian Hu, Wenli Yang et al. • Frontiers in Oncology (2022)

The outcomes of myelodysplastic syndrome (MDS) patients with SF3B1 mutation, despite identified as a favorable prognostic biomarker, are variable. To comprehend the heterogeneity in clinical characteristics and outcomes, we reviewed 140 MDS...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.905490

Ion Mobility Mass Spectrometry Reveals Rare Sialylated Glycosphingolipid Structures in Human Cerebrospinal Fluid

Mirela Sarbu, Dragana Fabris, Željka Vukelić, David E. Clemmer et al. • Molecules (2022)

Gangliosides (GGs) represent an important class of biomolecules associated with the central nervous system (CNS). In view of their special role at a CNS level, GGs are valuable diagnostic markers and prospective therapeutic agents. By ion m...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27030743

A novel sandwich ELISA method for quantifying CHI3L1 in blood serum and cerebrospinal fluid multiple sclerosis patients using sustainable photo-irradiated zero-valence gold nanoparticles

Marwa Saad Mohammed, Salwa H.N. Al-Rubaeꞌi, Ahmed Mahdi Rheima, Fatin Fadhel Al-Kazazz • Results in Chemistry (2024)

The widespread occurrence of chronic demyelinating MS presents a significant challenge for ongoing research aimed at comprehending its progression, diagnosis, and treatment. In our research, we have devised a novel approach to quantify CHI3...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rechem.2024.101856

A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

Henri Schmidt, Arutha Kulasinghe, Richard J.N. Allcock, Lit Yeen Tan et al. • Diagnostics (2018)

Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs. PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway. PIK3CA has been impl...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics8040079

Resting-state EEG measures cognitive impairment in Parkinson’s disease

Md Fahim Anjum, Arturo I. Espinoza, Rachel C. Cole, Arun Singh et al. • npj Parkinson's Disease (2024)

Abstract Cognitive dysfunction is common in Parkinson’s disease (PD). We developed and evaluated an EEG-based biomarker to index cognitive functions in PD from a few minutes of resting-state EEG. We hypothesized that synchronous changes in ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41531-023-00602-0

A Predictive Model Based on the Gut Microbiota Improves the Diagnostic Effect in Patients With Cholangiocarcinoma

Tan Zhang, Tan Zhang, Sina Zhang, Sina Zhang et al. • Frontiers in Cellular and Infection Microbiology (2021)

Cholangiocarcinoma (CCA) is a malignant hepatic tumor with a poor prognosis, which needs early diagnosis urgently. The gut microbiota has been shown to play a crucial role in the progression of liver cancer. Here, we explored a gut microbio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2021.751795

Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review

Samantha Hayward, Kevon Parmesar, Gavin I. Welsh, Matthew Suderman et al. • Biomedicines (2023)

A small subset of people with nephrotic syndrome (NS) have genetically driven disease. However, the disease mechanisms for the remaining majority are unknown. Epigenetic marks are reversible but stable regulators of gene expression with uti...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines11020514

Continuous monitoring biosensors for advanced healthcare and environmental applications: challenges, material innovations and future directions

Kiran Kumar Amireddy, P. V. R. Ravindra Reddy, C. Nagendranatha Reddy, P. Prabhakar Reddy • Frontiers in Sensors (2026)

This review critically discusses the development of continuous monitoring biosensors and the technological developments that have facilitated the transition from one-off or periodic measurement sensors to longer-term, connected and autonomo...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsens.2026.1968999

Application of Protein-Protein Interaction Network Analysis in Order to Identify Cervical Cancer miRNA and mRNA Biomarkers

Parinaz Tabrizi-Nezhadi, Habib MotieGhader, Masoud Maleki, Soner Sahin et al. • The Scientific World Journal (2023)

Cervical cancer (CC) is one of the world’s most common and severe cancers. This cancer includes two histological types: squamous cell carcinoma (SCC) and adenocarcinoma (ADC). The current study aims at identifying novel potential candidate ...

DOAJ Open Access (DOAJ) DOI: 10.1155/2023/6626279

Coalition of explainable artificial intelligence and quantum computing in precision medicine

Soumyadeep Ray, Pronaya Bhattacharya, Ebrahim A. Mattar, Abhishek Mukhopadhyay • Computational and Structural Biotechnology Journal (2025)

This survey examines the convergence of Explainable Artificial Intelligence (XAI) and Quantum Computing (QC) toward precision medicine. We review developments from 2018 to 2025, summarizing quantum algorithms, quantum-machine-learning model...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.csbj.2025.11.031

CircUCK2(2,3) promotes cancer progression and enhances synergistic cytotoxicity of lenvatinib with EGFR inhibitors via activating CNIH4–TGFα–EGFR signaling

Xindong Wei, Anfeng Si, Shuai Zhao, Yi Fu et al. • Cellular & Molecular Biology Letters (2025)

Abstract Background Circular (circ)RNAs have emerged as crucial contributors to cancer progression. Nonetheless, the expression regulation, biological functions, and underlying mechanisms of circRNAs in mediating hepatocellular carcinoma (H...

DOAJ Open Access (DOAJ) DOI: 10.1186/s11658-025-00690-1

Unrevealing the dual role of paired box and sex determining region Y related high mobility group box in glioblastoma

Kallol Polley, Sayed Mohammed Firdous • Discover Oncology (2026)

Abstract This narrative review summarises glioblastoma (GBM), a very frequent invasive kind of brain tumour in the elderly that is extremely aggressive, resistant to treatment, and has a bad prognosis because of its substantial genetic and ...

DOAJ Open Access (DOAJ) DOI: 10.1007/s12672-026-04671-4

Differential Expression of Serum TUG1, LINC00657, miR-9, and miR-106a in Diabetic Patients With and Without Ischemic Stroke

Omayma O Abdelaleem, Olfat G. Shaker, Mohamed M. Mohamed, Tarek I. Ahmed et al. • Frontiers in Molecular Biosciences (2022)

Background: Ischemic stroke is one of the serious complications of diabetes. Non-coding RNAs are established as promising biomarkers for diabetes and its complications. The present research investigated the expression profiles of serum TUG1...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmolb.2021.758742

Molecular Biology and Biotechnology

• Royal Society of Chemistry eBooks (2009)

One of the exciting aspects of being involved in the field of molecular biology is the ever-accelerating rate of progress, both in the development of new methodologies and the practical applications of these methodologies. This popular text...

OPENALEX DOI: https://doi.org/10.1039/9781849730211

Degradation of Organophosphorus and Pyrethroid Insecticides in Beverages: Implications for Risk Assessment

Samantha A. Radford, Parinya Panuwet, Ronald E. Hunter Jr., Dana Boyd Barr et al. • Toxics (2018)

Since urinary insecticide metabolites are commonly used as biomarkers of exposure, it is important that we quantify whether insecticides degrade in food and beverages in order to better perform risk assessment. This study was designed to qu...

DOAJ Open Access (DOAJ) DOI: 10.3390/toxics6010011