Academic Articles & Research Papers

Identification of Eusynstyelamide B as a Potent Cell Cycle Inhibitor Following the Generation and Screening of an Ascidian-Derived Extract Library Using a Real Time Cell Analyzer

Ascidians are marine invertebrates that have been a source of numerous cytotoxic compounds. Of the first six marine-derived drugs that made anticancer clinical trials, three originated from ascidian specimens. In order to identify new anti-...

Narratives of risk: Women at midlife, medical 'experts' and health technologies

The 'management' of midlife women's bodies is becoming an increasingly important focus for both themselves and medical 'experts'. Health technologies play a major part in this process, given health promotion messages about their usefulness ...

An assessment of the impact of the NHS Health Technology Assessment Programme

OBJECTIVES: To consider how the impact of the NHS Health Technology Assessment (HTA) Programme should be measured. To determine what models are available and their strengths and weaknesses. To assess the impact of the first 10 years of the ...

Evaluation of the Quality of Mobile Health Applications for Medication Adherence in Iran

Background & aim: Mobile health(mHealth) applications have emerged as pivotal tools for enhancing medication adherence, leveraging high accessibility and the widespread penetration of smartphones. The clinical effectiveness of these tools i...

Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran

Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran Background: Phenylketonuria is an autosomal recessive disease. Early diagnosis is a important public health intervention to prevent neurol...

Development of WEFIT Screening Tool for Assessing Pre-exercise Fitness Level for Older Adults in Peninsular Malaysia

Background: Pre-exercise screening is important to identify the fitness level of older adults prior to performing exercise. This study aimed to develop a screening tool for identifying older adults with poor physical fitness prior to exerci...

Treatment seeking behaviors related to gonorrhea among female sex workers in 7 cities in Indonesia

Abstrak Latar belakang:Gonore merupakan salah satu infeksi menular seksual yang menjadi permasalahan besar kesehatan terutama pada wanita penjaja seks (WPS) di Indonesia. Tujuan dari artikel ini adalah untuk melihat hubungan antara pola pen...

Health technology assessment in Finland

Since the 1990s, health policy makers in Finland have been supportive of evidence-based medicine and approaches to implement its results. The Finnish Office for Health Technology Assessment (Finohta) has grown from a small start in 1995 to ...

Barriers and facilitators of retention in care after cervical cancer screening: patients’ and healthcare providers’ perspectives

Abstract Background Cervical cancer continues to threaten women’s health, especially in low-resource settings. Regular follow-up after screening and treatment is an effective strategy for monitoring treatment outcomes. Consequently, underst...

Analysis of TORCH screening and prenatal risk assessment for childbearing-age women in different regions of China

Abstract Objective By conducting TORCH screening and risk assessment analysis on childbearing-age women in different regions of China, the aim is to provide reference for reducing adverse pregnancy outcomes and improving the health status o...

Adoption of e-health technology by physicians: a scoping review

OBJECTIVE: The goal of this scoping review was to summarize the current literature identifying barriers and opportunities that facilitate adoption of e-health technology by physicians. DESIGN: Scoping review. SETTING: MEDLINE, EMBASE, and P...

Inequities in Health Care Services Caused by the Adoption of Digital Health Technologies: Scoping Review

BACKGROUND: Digital health technologies (ie, the integration of digital technology and health information) aim to increase the efficiency of health care delivery; they are rapidly adapting to health care contexts to provide improved medical...

Hypermethylated PCDHGB7 as a universal cancer only marker and its application in early cervical cancer screening

Molecular Informatics, Chemometrics, and Sensory Omics for Constructing an Umami Peptide Cluster Library Across the Entire Lager Beer Brewing Process

Umami taste in lager beer not only determined body fullness and the backbone of aftertaste, but also affected the controllability and interpretability of flavor expression across the entire brewing process. Based on stage-wise sampling, pep...

The Colorectal Cancer Screening Programme in the Basque Country: obtaining a good performance by means of professional collaboration

Introduction: The Basque Health Service approved the Colorectal Cancer (CRC) screening programme in 2008; targeted at residents (50 to 69 years old) estimated 598,201 by biennial faecal immunochemical test (FIT) and colonoscopy in positive ...

Full-thickness skin graft versus split-thickness skin graft for radial forearm free flap donor site closure: protocol for a systematic review and meta-analysis

Abstract Background The radial forearm free flap (RFFF) serves as a workhorse for a variety of reconstructions. Although there are a variety of surgical techniques for donor site closure after RFFF raising, the most common techniques are cl...

Artificial neural network–based model for sleep quality prediction for frontline medical staff during major medical assistance

Background: The sleep quality of medical staff was severely affected during COVID-19, but the factors influencing the sleep quality of frontline staff involved in medical assistance remained unclear, and screening tools for their sleep qual...

DeltaProt: a software toolbox for comparative genomics

Abstract Background Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding of environmental adaptations of proteins, orthologous ...

Isolation, characterisation and antibiotic susceptibility of staphylococcal isolates with special reference to methicillin-resistant Staphylococcus aureus from the anterior nares of healthcare workers in A tertiary healthcare centre

Background: Staphylococcus aureus (S. aureus) and its resistant form methicillinresistant S. aureus (MRSA) is one of the most common nosocomial pathogens causing a wide range of infections in humans. The anterior nares are the main ecologic...

‘Optimal’ cutoff selection in studies of depression screening tool accuracy using the PHQ‐9, EPDS, or HADS‐D: A meta‐research study

Abstract Objectives Optimal cutoff thresholds are selected to separate ‘positive’ from ‘negative’ screening results. We evaluated how depression screening tool studies select optimal cutoffs. Methods We included studies from previously cond...