Academic Articles & Research Papers

Predicting Parameters in Deep Learning

We demonstrate that there is significant redundancy in the parameterization of several deep learning models. Given only a few weight values for each feature it is possible to accurately predict the remaining values. Moreover, we show that n...

MMSplice: modular modeling improves the predictions of genetic variant effects on splicing

Abstract Predicting the effects of genetic variants on splicing is highly relevant for human genetics. We describe the framework MMSplice (modular modeling of splicing) with which we built the winning model of the CAGI5 exon skipping predic...

Scalable and accurate deep learning with electronic health records

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor variabl...

Predicting cell-state-specific gene regulation from DNA across species.

Credit card fraud detection in the era of disruptive technologies: A systematic review

Credit card fraud is becoming a serious and growing problem as a result of the emergence of innovative technologies and communication methods, such as contactless payment. In this article, we present an in-depth review of cutting-edge resea...

Comprehensive framework of machine learning and deep learning architectures with metaheuristic optimization for high-fidelity prediction of nanofluid specific heat capacity

Abstract Accurately predicting the specific heat capacity of nanofluids is critical for optimizing their performance in engineering and industrial applications. This study explores twelve machine learning and deep learning models using conv...

Predicting Shield Machine Penetration Rate Using the CTCM-DELM Algorithm

The penetration rate (PR) is a critical indicator affecting the safety and cost of shield tunnel construction. However, due to the complexity of geological conditions and the nonlinear nature of tunneling parameters, traditional prediction ...

Predicting process behaviour using deep learning

Prediction of lymph node metastasis in papillary thyroid carcinoma using non-contrast CT-based radiomics and deep learning with thyroid lobe segmentation: A dual-center study

Objectives: This study aimed to develop a predictive model for lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) patients by deep learning radiomic (DLRad) and clinical features. Methods: This study included 271 thyroid lobes...

Deep Learning Proactive Approach to Blackout Prevention in Smart Grids: An Early Warning System

Blackout events in smart grids can have significant impacts on individuals, communities and businesses, as they can disrupt the power supply and cause damage to the grid. In this paper, a new proactive approach to an early warning system fo...

DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs

The rational design of PROTACs is difficult due to their obscure structure-activity relationship. Here the authors present a deep neural network model - DeepPROTACs - for predicting the degradation capacity of a proposed PROTAC molecule....

Gaze Point Estimation via Joint Learning of Facial Features and Screen Projection

In recent years, gaze estimation has received a lot of interest in areas including human–computer interface, virtual reality, and user engagement analysis. Despite significant advances in convolutional neural network (CNN) techniques, direc...

MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites

Abstract Malaria remains one of the deadliest infectious diseases. Transcriptional regulation effects of noncoding variants in this unusual genome of malaria parasites remain elusive. We developed a sequence-based, ab initio deep learning f...

A deep learning approach to predict blood-brain barrier permeability

The blood–brain barrier plays a crucial role in regulating the passage of 98% of the compounds that enter the central nervous system (CNS). Compounds with high permeability must be identified to enable the synthesis of brain medications for...

ACtriplet: An improved deep learning model for activity cliffs prediction by integrating triplet loss and pre-training

Activity cliffs (ACs) are generally defined as pairs of similar compounds that only differ by a minor structural modification but exhibit a large difference in their binding affinity for a given target. ACs offer crucial insights that aid m...

A Survey on Deep Learning for Steering Angle Prediction in Autonomous Vehicles

Steering angle prediction is critical in the control of Autonomous Vehicles (AVs) and has attracted the attention of researchers, manufacturers, and insurance companies in the automotive industry. Different Deep Learning (DL) architectures ...

Computational Linguistics and Deep Learning

Deep Learning waves have lapped at the shores of computational linguistics for several years now, but 2015 seems like the year when the full force of the tsunami hit the major Natural Language Processing (NLP) conferences. However, some pun...

Using deep learning to predict tyrosinase inhibitors for treating hyperpigmentation disorders

Background In recent years, skin health has garnered widespread attention, with hyperpigmentation disorders caused by excessive melanin deposition emerging as a particularly prominent concern. Tyrosinase, as the rate-limiting enzyme in the ...

Deep learning-based MRI model for predicting P53-mutated hepatocellular carcinoma

Abstract Background The P53-mutated Hepatocellular Carcinoma (HCC) is an aggressive variant associated with vascular endothelial growth factor (VEGF) overexpression and increased microvascular density. This study aimed to develop an MRI-bas...

Machine learning and data-driven prediction of pore pressure from geophysical logs: A case study for the Mangahewa gas field, New Zealand

Pore pressure is an essential parameter for establishing reservoir conditions, geological interpretation and drilling programs. Pore pressure prediction depends on information from various geophysical logs, seismic, and direct down-hole pre...