Academic Articles & Research Papers

Program-Based Lung Cancer Care: A Prospective Observational Tumor Registry Linkage Study

Introduction: Low-dose computed tomography screening (LDCT) and lung nodule programs (LNP) promote early lung cancer detection, improve survival; Multidisciplinary Care Programs (MDC) promote guideline-concordant care. The impact of such pr...

Seaweed-Derived Sulfated Polysaccharides as Potential Agents for Prevention and Treatment of Influenza and COVID-19

The review presents materials describing the seaweed-derived sulfated polysaccharides (SPS) as potential means for prevention and treatment of viral diseases of the respiratory tract, mainly influenza and COVID-19. The literature materials o...

Using Wearable Devices to Examine the Associations of Sedentary Behavior with Perceived and Performance Fatigability Among Older Adults: The Study of Muscle, Mobility and Aging (SOMMA)

Fatigability, a phenotype of poor energy regulation, is associated with lower physical activity in older adults, but independent associations with sedentary behavior are unknown. We examined whether sedentary behavior was associated with fa...

Nutritional status, literacy, and risk factors of malnutrition in the population over 50 years of age - findings from the SHARE project

Summary: Background & Aims: The transition from middle age to old age (from adults aged 50–55 years to older seniors aged 75–80 years) represents a critical period in terms of changes in body composition, i.e., increase in body fat per...

Having More Daughters Independently Predicts Home Discharge in Stroke Patients Admitted to Inpatient Rehabilitation Ward

Background: The predictors for failure of home discharge after post-acute inpatient stroke rehabilitation need investigation. Methods: With this retrospective case-control study conducted in a stroke rehabilitation unit in one tertiary hosp...

Lipofuscin: Wear Pigment or Alarm Signal for Cardiac AlloGraft Vasculopathy?

Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...

Prevalence of Congenital Anomalies in the Northwest of Iran

Background and Objectives Every year, about three hundred thousands of infant deaths occur because of congenital anomalies. Some continue to live with various types of disabilities. Low and middle income countries have higher rate of congen...

Threshold dynamics of a delayed predator–prey model with impulse via the basic reproduction number

Abstract In this paper, we study a delayed predator–prey model with impulse and, in particular, the existence of the predator-free periodic solution. We employ the approach and techniques coming from epidemiology and calculate the basic rep...

Mathematical Models in Epidemiology

An Introduction to Mathematical Epidemiology

Mathematical Epidemiology

The economics of TAVI: A systematic review

Objective: The scope of this systematic review is to update the existing body of evidence regarding the cost-effectiveness of transcatheter aortic valve implantation, stratified across all risk categories, and to assess their methodological...

Visit-to-visit variability of serum uric acid measurements and the risk of all-cause mortality in the general population

Abstract Background Evidence on longitudinal variability of serum uric acid (SUA) and risk of all-cause mortality in the general population is limited, as many prior studies focused on a single measurement of SUA. Methods A total of 53,956 ...

Feasibility study for interactive reporting of network meta-analysis: experiences from the development of the MetaInsight COVID-19 app for stakeholder exploration, re-analysis and sensitivity analysis from living systematic reviews

Abstract Background Network meta-analysis (NMA) has been increasingly adopted worldwide by Cochrane reviews, guideline developers and decision-making bodies to identify optimal treatment choices. However, NMA results are often produced stat...

Neurotoxicity of PM_2.5-Bound Multi-Pollutant Mixtures in Parkinson’s Disease: Exploring the <i>INPP5D</i>/SHIP1-PI3K-AKT Axis via an Integrative Multi-Omics Study

Accumulating epidemiological evidence links ambient PM2.5 exposure to elevated Parkinson’s disease (PD) risk, yet the neurotoxicity triggered by PM2.5 multi-pollutant mixtures under real co-exposure scenarios remains insufficiently elucidat...

Changes in the comprehensive unassisted pregnancy rate as a possible marker of declining human fecundity

Abstract Recent decades have seen declining total fertility rates (TFR) globally, alongside increased use of assisted reproductive technology (ART). However, TFR includes ART births and excludes induced abortions, complicating assessments o...

Evaluation of the Quality of Mobile Health Applications for Medication Adherence in Iran

Background & aim: Mobile health(mHealth) applications have emerged as pivotal tools for enhancing medication adherence, leveraging high accessibility and the widespread penetration of smartphones. The clinical effectiveness of these tools i...

Association between maternal plasma glucose levels during pregnancy and risk of preterm birth: a retrospective study

Abstract Background Preterm birth is a leading cause of health problems and death in infants. This study aims to investigate the association between maternal plasma glucose levels during pregnancy and risk of preterm birth. Methods This pop...

Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran

Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran Background: Phenylketonuria is an autosomal recessive disease. Early diagnosis is a important public health intervention to prevent neurol...

Characterization of swine-origin H1N1 canine influenza viruses

Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province of China. This host switch was fo...