Academic Articles & Research Papers

Improving cognitive impairment classification in Alzheimer’s disease using tabular diffusion augmentation and late fusion deep learning.

Understanding of Machine Learning with Deep Learning: Architectures, Workflow, Applications and Future Directions

In recent years, deep learning (DL) has been the most popular computational approach in the field of machine learning (ML), achieving exceptional results on a variety of complex cognitive tasks, matching or even surpassing human performance...

Accuracy of machine learning for differentiation between optic neuropathies and pseudopapilledema

Abstract Background This study is to evaluate the accuracy of machine learning for differentiation between optic neuropathies, pseudopapilledema (PPE) and normals. Methods Two hundred and ninety-five images of optic neuropathies, 295 images...

Deep learning improves antimicrobial peptide recognition

Motivation: Bacterial resistance to antibiotics is a growing concern. Antimicrobial peptides (AMPs), natural components of innate immunity, are popular targets for developing new drugs. Machine learning methods are now commonly adopted by w...

DVNDTA: a dual virtual node based heterogeneous interaction model for accurate prediction of drug-target affinity

Abstract Efficient prediction of drug-target affinity (DTA) is crucial for accelerating drug discovery. Recently, deep learning approaches leveraging 3D complexes have shown strong potential for drug-target affinity prediction. However, mos...

A State-of-the-Art Survey on Deep Learning Theory and Architectures

In recent years, deep learning has garnered tremendous success in a variety of application domains. This new field of machine learning has been growing rapidly and has been applied to most traditional application domains, as well as some ne...

Intelligent diagnosis with Chinese electronic medical records based on convolutional neural networks

Abstract Background Benefiting from big data, powerful computation and new algorithmic techniques, we have been witnessing the renaissance of deep learning, particularly the combination of natural language processing (NLP) and deep neural n...

Deep Learning and Medical Diagnosis: A Review of Literature

In this review the application of deep learning for medical diagnosis is addressed. A thorough analysis of various scientific articles in the domain of deep neural networks application in the medical field has been conducted. More than 300 ...

Gene expression inference with deep learning

MOTIVATION: Large-scale gene expression profiling has been widely used to characterize cellular states in response to various disease conditions, genetic perturbations, etc. Although the cost of whole-genome expression profiles has been dro...

Revisiting batch effect correction: a structured problem formulation and novel solutions.

Deep Learning and Its Applications in Biomedicine

Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data, such as medical images, electroencephalography, genomic and protein sequences. Learning from these data facilitat...

Ensemble deep learning in bioinformatics

Applications for deep learning in ecology

Abstract A lot of hype has recently been generated around deep learning, a group of artificial intelligence approaches able to break accuracy records in pattern recognition. Over the course of just a few years, deep learning revolutionized ...

Deep Learning for Health Informatics

With a massive influx of multimodality data, the role of data analytics in health informatics has grown rapidly in the last decade. This has also prompted increasing interests in the generation of analytical, data driven models based on mac...

Deep learning for computational biology

Technological advances in genomics and imaging have led to an explosion of molecular and cellular profiling data from large numbers of samples. This rapid increase in biological data dimension and acquisition rate is challenging conventiona...

Deep learning in bioinformatics

In the era of big data, transformation of biomedical big data into valuable knowledge has been one of the most important challenges in bioinformatics. Deep learning has advanced rapidly since the early 2000s and now demonstrates state-of-th...

Deep Learning

Deep learning is a form of machine learning that enables computers to learn from experience and understand the world in terms of a hierarchy of concepts. Because the computer gathers knowledge from experience, there is no need for a human c...

Ten quick tips for machine learning in computational biology

Machine learning has become a pivotal tool for many projects in computational biology, bioinformatics, and health informatics. Nevertheless, beginners and biomedical researchers often do not have enough experience to run a data mining proje...

Machine learning and its applications: A review

Nowadays, large amount of data is available everywhere. Therefore, it is very important to analyze this data in order to extract some useful information and to develop an algorithm based on this analysis. This can be achieved through data m...

Automated cell type annotation and exploration of single-cell signaling dynamics using mass cytometry

Summary: Mass cytometry by time-of-flight (CyTOF) is an emerging technology allowing for in-depth characterization of cellular heterogeneity in cancer and other diseases. Unfortunately, high-dimensional analyses of CyTOF data remain quite d...