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Showing 20 of 2,986 academic articles

Green Microfluidic Method for Sustainable and High-Speed Analysis of Basic Amino Acids in Nutritional Supplements

Iva Pukleš, Csilla Páger, Nikola Sakač, Bojan Šarkanj et al. • Molecules (2024)

Amino acids (AAs) have broad nutritional, therapeutic, and medical significance and thus are one of the most common active ingredients of nutritional supplements. Analytical strategies for determining AAs are high-priced and often limited t...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules29235554

Expression Profiles of IGF1, EGF, and FGF2 Genes in Patients With Prostate Cancer in Isfahan Province, Iran

Farinaz Khosravian, Fatemeh Ketabchi, Nasrin Hadi, Faezeh Namazi et al. • Research in Molecular Medicine (2019)

Background: Prostate cancer is the second most prevalent cancer among men all over the world. Over the past 10 years, prostate cancer prevalence has increased in Iran. Growth factors have an important role in the regulation and growth of ma...

DOAJ Open Access (DOAJ)

Expression of Recombinant Human Amelogenin in Iranian Lizard Leishmania and Its Biological Function Assay

Zahra YADEGARI, Mojgan BANDEHPOUR, Bahram KAZEMI, Khojasteh SHARIFI-SARASIABI • Iranian Journal of Public Health (2015)

Background: Amelogenins are the major components of enamel matrix proteins. Enamel matrix derivatives (EMD) can be used in periodontal diseases to regenerate periodontal tissues. The main aim of this study was to evaluate ex-pression of ful...

DOAJ Open Access (DOAJ)

RETRACTED ARTICLE: Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus

Vassilis L. Souliotis, Konstantinos Vougas, Vassilis G. Gorgoulis, Petros P. Sfikakis • Arthritis Research & Therapy (2016)

Abstract Background Excessive autoantibody production characterizing systemic lupus erythematosus (SLE) occurs irrespective of the disease’s clinical status and is linked to increased lymphocyte apoptosis. Herein, we tested the hypothesis t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13075-016-1081-3

Extramedullary plasmacytoma of the oral cavity metastasising to both kidneys in a dog

Kyung Ho Park, Tae‐Un Kim, Hyun‐Woo Park, Seoung‐Woo Lee et al. • Veterinary Medicine and Science (2023)

Abstract Background Most extramedullary plasmacytomas (EMPs) aresolitary and located in the head and neck region. They may also occur in the visceral parts of the body. Objectives Here, we report a case of oral EMP followed by neoplastic pl...

DOAJ Open Access (DOAJ) DOI: 10.1002/vms3.1086

Chromosomal Instability in Various Generations of Human Mesenchymal Stem Cells Following the Therapeutic Radiation

Majid Sadeghi Moghadam, Hosein Azimian, Jalil Tavakol Afshari, Mohammad Taghi Bahreyni Toossi et al. • Stem Cells International (2023)

Background. Radiotherapy is a crucial treatment for most malignancies. However, it can cause several side effects, including the development of secondary malignancies due to radiation-induced genomic instability (RIGI). The aim of this stud...

DOAJ Open Access (DOAJ) DOI: 10.1155/2023/9991656

Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study

Md. Jamal Hossain, Foyez Ahmmed, Md. Robin Khan, Parisa Tamannur Rashid et al. • Frontiers in Nutrition (2022)

ObjectivesThis current study aims to assess the prevalence and factors associated with body mass index (BMI), dietary patterns, and the extent of physical activities among university students following the prolonged coronavirus disease 2019...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2022.873105

Expanding the genetic spectrum of hereditary motor sensory neuropathies in Pakistan

Asif Naveed Ahmed, Lettie E. Rawlins, Niamat Khan, Zakir Jan et al. • BMC Neurology (2024)

Abstract Background Hereditary motor and sensory neuropathy (HMSN) refers to a group of inherited progressive peripheral neuropathies characterized by reduced nerve conduction velocity with chronic segmental demyelination and/or axonal dege...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12883-024-03882-y

Histone deacetylase 3 deletion in alveolar type 2 epithelial cells prevents bleomycin-induced pulmonary fibrosis

Rui Xiong, Boxin Geng, Wenyang Jiang, Yong Hu et al. • Clinical Epigenetics (2023)

Abstract Background Epithelial mesenchymal transformation (EMT) in alveolar type 2 epithelial cells (AT2) is closely associated with pulmonary fibrosis (PF). Histone deacetylase 3 (HDAC3) is an important enzyme that regulates protein stabil...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13148-023-01588-5

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450

PRODUCTION OF L-TRYPTOPHAN BY MUTANTS OF CORYNEBACTERIUM GLUTAMICUM

Hamies Mohamed, Ghada El Nady, A. Ali, A. Abdel-Razik et al. • Arab Universities Journal of Agricultural Sciences (2018)

L-Tryptophan, is one of the amino acids, also is one of the 9 essential amino acids of human which cannot be synthesized internally by him, microbial production is the main method for obtaining tryptophan for commercial uses. Typical microo...

DOAJ Open Access (DOAJ) DOI: 10.21608/ajs.2018.28383

Comparative Phytochemical Analysis of the Aerial Parts of <i>Pelargonium radula</i> and <i>Geranium macrorrhizum</i> Cultivated in Bulgaria Using GC-MS and HPLC

Debora Sabotinova, Petya Boycheva, Nadezhda Ivanova, Velichka Andonova et al. • Pharmaceuticals (2026)

Background: Geraniaceae species are widely used in traditional medicine. Pelargonium radula and Geranium macrorrhizum are aromatic medicinal plants traditionally used in Bulgaria for their antimicrobial, anti-inflammatory, and wound-healing...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph19030346

Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

Xinbo Wang, Jiaying Miao, Sizhen Wang, Rongxi Shen et al. • Molecular Cancer (2022)

Abstract Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical features. Me...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-022-01596-8

Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis

Mengqiang Fan, Peijian Tong, Li Yan, Ting Li et al. • BMC Medicine (2023)

Abstract Background Articular injection of mesenchymal stem cells (MSCs) has been applied to treat knee osteoarthritis (kOA), but its clinical outcomes are controversial. This study investigated whether an articular inflammatory microenviro...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12916-023-02923-6

Absence of Asymptomatic Malaria Infection in Endemic Area of Bashagard District, Hormozgan Province, Iran

H Turki, S Zoghi, A A Mehrizi, S Zakeri et al. • Iranian Journal of Parasitology (2012)

Background: A successful malaria elimination program calls for enough attention to parasite carri­ers, especially asymptomatic malaria, as well as the diagnosis and treatment of clinical cases. Asymptomatic malaria is an infection that pati...

DOAJ Open Access (DOAJ)

Medical Biotechnology - Approaches to become an Entrepreneur in Medical Biotechnology

Antony Vincent Samrot, Sanjay Preeth R., M. Bavanilatha • BENTHAM SCIENCE PUBLISHERS eBooks (2024)

Medical biotechnology is one of its branches which involves the application of medicine and biotechnology resources. Entrepreneurship is said to be the development of a new business making profits where innovation and creditability are cons...

OPENALEX DOI: https://doi.org/10.2174/9789815196115124010017

Relationship between Perceived Social Support in First Pregnancy with Birth Satisfaction in Primigravid Women Referred to Shahid Akbar Abadi Hospital

homa sadeghi aval shahr, sayeh sadat moosavi sahebalzamani, freshteh jahdi, leila neisani samani et al. • Preventive Care in Nursing and Midwifery Journal (2014)

Background and Objectives: Recent studies have shown that social and environmental factors as well as social communication play crucial role in pregnancy outcomes. The current study aimed to examine the relationship between perceived social...

DOAJ Open Access (DOAJ)

Regulatory requirements for the registration of generic medicines and format of drug dossiers: procedures in Sri Lanka in comparison with selected regulatory authorities

D. Thambavita, P. Galappatthy, R. L. Jayakody • Journal of Pharmaceutical Policy and Practice (2018)

Background The regulatory requirements for approval of generic medicines and the format of compiling drug dossiers vary among regulatory authorities. The variation is particularly wide between High-income countries (HIC) and lower and middl...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40545-018-0141-2