Academic Articles & Research Papers

Low Pathogenic Avian Influenza H9N2 Viruses in Morocco: Antigenic and Molecular Evolution from 2021 to 2023

Avian influenza viruses pose significant threats to both the poultry industry and public health worldwide. Among them, the H9N2 subtype has gained substantial attention due to its high prevalence, especially in Asia, the Middle East, and Af...

β-Cell Death in Diabetes: Past Discoveries, Present Understanding, and Potential Future Advances

β-cell death is regarded as a major event driving loss of insulin secretion and hyperglycemia in both type 1 and type 2 diabetes mellitus. In this review, we explore past, present, and potential future advances in our understanding of the m...

Extracellular vesicles derived from mesenchymal stromal cells mitigate intestinal toxicity in a mouse model of acute radiation syndrome

Abstract Background Human exposure to high doses of radiation resulting in acute radiation syndrome and death can rapidly escalate to a mass casualty catastrophe in the event of nuclear accidents or terrorism. The primary reason is that the...

A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss

Selenoprotein N (SELENON) is an endoplasmic reticulum (ER) protein whose loss of function leads to human SELENON-related myopathies. SelenoN knockout (KO) mouse limb muscles, however, are protected from the disease, and display no major alt...

Beginning at the ends: telomeres and human disease [version 1; referees: 4 approved]

Studies of rare and common illnesses have led to remarkable progress in the understanding of the role of telomeres (nucleoprotein complexes at chromosome ends essential for chromosomal integrity) in human disease. Telomere biology disorders...

Transgenerational inheritance of ethanol preference is caused by maternal NPF repression

Rapid or even anticipatory adaptation to environmental conditions can provide a decisive fitness advantage to an organism. The memory of recurring conditions could also benefit future generations; however, neuronally-encoded behavior isn’t ...

P415: TARGETED 3RD-GENERATION (NANOPORE) SEQUENCING REVEALS MANY NOVEL CIRCULAR RNAS OF THE APOPTOSIS-RELATED BCL2L12 GENE, EXPRESSED IN HUMAN CELLS FROM ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROMES

Nanotechnology and medicine

Nanotechnology, or systems/device manufacture at the molecular level, is a multidisciplinary scientific field undergoing explosive development. The genesis of nanotechnology can be traced to the promise of revolutionary advances across medi...

Nanotechnology

Human dreams and imagination often give rise to new science and technology. Nanotechnology, a 21st-century frontier, was born out of such dreams. Nanotechnology is defined as the understanding and control of matter at dimensions between 1 a...

Designing a Model for Improving Small and Medium-Sized Enterprises (SMEs)

Business improvement has always been one of the basic issues in the business world. Due to the growing changes in technology, pervasive competition and the changing needs of customers, companies must pay attention to the permanence and impr...

Real time groupware as a distributed system

This paper exposes the concurrency control problem in groupware when it is implemented as a distributed system. Traditional concurrency control methods cannot be applied directly to groupware because system interactions include people as we...

A systems-level energetic framework for conscious processing: energetic organization as a constraint on large-scale neural integration

Conscious processing is associated with coordinated interactions among distributed neural systems, yet the biological constraints that enable and sustain large-scale neural integration remain incompletely understood. Contemporary theories e...

Three-Dimensional Physical and Optical Characteristics of Aerosols over Central China from Long-Term CALIPSO and HYSPLIT Data

Aerosols greatly influence global and regional atmospheric systems, and human life. However, a comprehensive understanding of the source regions and three-dimensional (3D) characteristics of aerosol transport over central China is yet to be...

Psychometric facets of Antifragility: Tolerance of Ambiguity, Hardiness, and Growth

This paper considers the issues, which are concerned with a new concept of antifragility. Quite recently, considerable attention has been paid to the concept of antifragility. Antifragility gains a special importance in studying psychologic...

Plasmodium vivax Transmission in Africa.

Malaria in sub-Saharan Africa has historically been almost exclusively attributed to Plasmodium falciparum (Pf). Current diagnostic and surveillance systems in much of sub-Saharan Africa are not designed to identify or report non-Pf human m...

An Organizational View of Distributed Systems

The relationship between organization theory and distributed systems is studied. By viewing distributed systems as analogous to human organizations, concepts and theories germane to the management science field of organization theory can be...

Early Stage Risk Identification and Governance of Major Emerging Infectious Diseases: A Double-Case Study Based on the Chinese Context

Xuefeng Li,1,2 Hui Jiang,1 Xiaoyu Liang1 1School of Engineering Science, University of Chinese Academy of Sciences, Beijing, 100049, People’s Republic of China; 2School of Public Policy and Management, University of Chinese Academy of Scien...

Encyclopedia of software engineering

Software engineering requires specialized knowledge of a broad spectrum of topics, including the construction of software; the platforms, applications and environments in which the software operates; as well as an understanding of the peopl...

Prevalence of comorbid depression and associated factors among hospitalized patients with type 2 diabetes mellitus in Hunan, China

Abstract Background Depression and diabetes are major health challenges, with heavy economic social burden, and comorbid depression in diabetes could lead to a wide range of poor health outcomes. Although many descriptive studies have highl...

An Explainable AI-Driven Zero-Day Attack Detection Framework for Securing Edge Devices in Smart Cities

The rapid proliferation of edge computing in smart cities has enhanced real-time data processing capabilities, but it has also exposed critical vulnerabilities to sophisticated cyber threats such as zero-day attacks. Traditional signature-b...