Reset
Showing 20 of 3,336 academic articles

تأثير برنامج تأهيلي بإستخدام الوسط المائي على بعض المتغيرات البدنية والفسيولوجية لدى اﻷطفال المصابين بالشلل الدماغي

محمد صلاح الدين محمد محمد, محمد نادر شلبي, آية طارق السيد خليل صيام • Mağallaẗ Buḥūṯ Al-Tarbiyyaẗ Al-Badaniyyaẗ wa ʿulūm Al-Rīyāḍaẗ (2025)

يهدف البحث الى محاولة التعرف علي "تأثير برنامج تأهيلى بإستخدام الوسط المائي على بعض المتغيرات البدنية والفسيولوجية لدى الأطفال المصابين بالشلل الدماغي" وقد استخدمت الباحثة المنهج التجريبي لمجموعة تجريبية واحدة بإستخدام التصميم التجريبي (الق...

DOAJ Open Access (DOAJ) DOI: 10.21608/osdj.2025.427259.1197

Assessment of Quality of Life and Social Correlates among Drug Sensitive and Multidrug-resistant Tuberculosis Patients

G. Hamsaveni, A. M. Amrutha, Bhagyalaxmi Sidenur, Vijayalaxmi Mangasuli et al. • Journal of Association of Pulmonologist of Tamil Nadu (2024)

Background: Tuberculosis (TB) has significant health, social, psychological, and economic impacts on patients. This study aimed to assess and compare quality of life (QOL) among multidrug-resistant (MDR) TB patients and drug-sensitive TB pa...

DOAJ Open Access (DOAJ) DOI: 10.4103/japt.japt_14_24

Effects of Interval Training Under Hypoxia on Hematological Parameters, Hemodynamic Function, and Endurance Exercise Performance in Amateur Female Runners in Korea

Hun-Young Park, Hun-Young Park, Won-Sang Jung, Won-Sang Jung et al. • Frontiers in Physiology (2022)

Interval training under hypoxia (IHT) is commonly used to enhance endurance exercise performance. However, previous studies examining hematologic changes related to the immune system that affect health and conditioning are lacking. This stu...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2022.919008

Application of Instrumented Paddles in Measuring On-Water Kinetics of Front and Back Paddlers in K2 Sprint Kayaking Crews of Various Ability Levels

Pui Wah Kong, Cheryl Sihui Tay, Jing Wen Pan • Sensors (2020)

This study used instrumented paddles to obtain on-water kinetic variables of two-seater (K2) crews during sprint kayaking. A total of 74 male kayakers of various ability levels (national team: 9, recreational club: 38, school team: 27) comp...

DOAJ Open Access (DOAJ) DOI: 10.3390/s20216317

Eenmaal iets dappers deur Annelie Ferreira

D. F. van Tonder • Acta Theologica (2001)

Uit teks: Met die woord vooraf neem die outeur ’n vertrekpunt in wat beslis dapper is. Sy beweer dat mense intens bewus is van die onpeilbaarheid van daardie wonderlike kragtige en misterieuse mag wat hulle soms “god” noem en soms iets ande...

DOAJ Open Access (DOAJ) DOI: 10.38140/at.v21i1.1538

Paths to Diversity: A Simulation of Conformity in Environments with Different Geometries

Matteo Colombo, Michael Cohen • Ergo, An Open Access Journal of Philosophy (2025)

The geometry of the environment can affect numerous psychological, social, and ecological processes. But its roles in social learning and the dynamics of descriptive norms remain unclear. Here we use agent-based modeling to explore how envi...

DOAJ Open Access (DOAJ) DOI: 10.3998/ergo.8584

Does Practice Make Perfect? The Effects of an Eight-Week Manualized Deliberate Practice Course With Peer Feedback on Patient-Rated Working Alliance in Adults: A Pilot Randomized Controlled Trial

Håkan Lagerberg, James F. Boswell, Michael J. Constantino, Gerhard Andersson et al. • Clinical Psychology in Europe (2024)

[Background] Deliberate Practice (DP), which underscores the importance of expert mentorship, personalized learning objectives, feedback, and repetition, has been suggested as a method to enhance the effectiveness of therapists. [Method] Th...

DOAJ Open Access (DOAJ) DOI: 10.32872/cpe.12353

Curcumin Inhibits Growth of Human NCI-H292 Lung Squamous Cell Carcinoma Cells by Increasing FOXA2 Expression

Lingling Tang, Jinjin Liu, Linyun Zhu, Qingge Chen et al. • Frontiers in Pharmacology (2018)

Lung squamous cell carcinoma (LSCC) is a common histological lung cancer subtype, but unlike lung adenocarcinoma, limited therapeutic options are available for treatment. Curcumin, a natural compound, may have anticancer effects in various ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2018.00060

Epoetin zeta in the management of anemia associated with chronic kidney disease, differential pharmacology and clinical utility

Davis-Ajami ML, Wu J, Downton K, Ludeman E et al. • Biologics: Targets & Therapy (2014)

Mary Lynn Davis-Ajami,1 Jun Wu,2 Katherine Downton,3 Emilie Ludeman,3 Virginia Noxon4 1Organizational Systems and Adult Health, University of Maryland School of Nursing, Baltimore, MD, USA; 2South Carolina College of Pharmacy, University of...

DOAJ Open Access (DOAJ)

Low-grade chronic inflammation and transcriptomics: how molecular pharmacognosy can help find new natural treatment alternatives—a narrative review

Massimo Fioranelli, Maria Grazia Roccia, Bianca Przybylek, Francesca Romana Sconci et al. • Beni-Suef University Journal of Basic and Applied Sciences (2024)

Abstract Background The inflammatory response is fundamental to the maintenance of an organism’s physiological homeostasis. Inflammation is controlled by a series of biological events driven by specific inflammatory molecules. When inflamma...

DOAJ Open Access (DOAJ) DOI: 10.1186/s43088-024-00506-9

Insufficient Expression of Cyclooxygenase-2 Protein Is Associated With Retarded Degradation of Aggregated Protein in Diabetic Glomeruli

Yasushi Hirasawa, Aiko Muramatsu, Yoshio Suzuki, Tadashi Nagamatsu • Journal of Pharmacological Sciences (2006)

To elucidate the involvement of cyclooxygenase (COX) in degradation of aggregated protein in diabetic glomeruli, we used streptozotocin (STZ)-induced diabetic mice and aggregated bovine serum albumin (a-BSA) as a model protein. There was a ...

DOAJ Open Access (DOAJ) DOI: 10.1254/jphs.FPJ06010X

Exercise Training and Circulating Small Extracellular Vesicles: Appraisal of Methodological Approaches and Current Knowledge

Ian A. J. Darragh, Lorraine O’Driscoll, Lorraine O’Driscoll, Lorraine O’Driscoll et al. • Frontiers in Physiology (2021)

In response to acute exercise, an array of metabolites, nucleic acids, and proteins are enriched in circulation. Collectively termed “exercise factors,” these molecules represent a topical area of research given their speculated contributio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2021.738333

Progress and Prospects of Non-Canonical NF-κB Signaling Pathway in the Regulation of Liver Diseases

Li Tao, Xiaomeng Ren, Wenhui Zhai, Zheng Chen • Molecules (2022)

Non-canonical nuclear factor kappa B (NF-κB) signaling pathway regulates many physiological and pathological processes, including liver homeostasis and diseases. Recent studies demonstrate that non-canonical NF-κB signaling pathway plays an...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27134275

Molecular Dynamics and In Vitro Studies Elucidating the Tunable Features of Reconfigurable Nanodiscs for Guiding the Optimal Design of Curcumin Formulation

Yongxiao Li, Wanting Xu, Xinpei Wang, Ruizhi Lai et al. • Bioengineering (2024)

In this study, we advance our exploration of Apolipoprotein A-I (apoA-I) peptide analogs (APAs) for their application in nanodisc (ND) assembly, focusing on the dynamic conformational characteristics and the potential for drug delivery. We ...

DOAJ Open Access (DOAJ) DOI: 10.3390/bioengineering11030245

Increased expression of glutathione peroxidase 3 prevents tendinopathy by suppressing oxidative stress

Haruka Furuta, Mari Yamada, Takuya Nagashima, Shuichi Matsuda et al. • Frontiers in Pharmacology (2023)

Tendinopathy, a degenerative disease, is characterized by pain, loss of tendon strength, or rupture. Previous studies have identified multiple risk factors for tendinopathy, including aging and fluoroquinolone use; however, its therapeutic ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2023.1137952

Perspective on the Therapeutics of Anti-Snake Venom

Isabel Gómez-Betancur, Vedanjali Gogineni, Andrea Salazar-Ospina, Francisco León • Molecules (2019)

Snakebite envenomation is a life-threatening disease that was recently re-included as a neglected tropical disease (NTD), affecting millions of people in tropical and subtropical areas of the world. Improvement in the therapeutic approaches...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules24183276

Lactobacillus brevis 23017 Relieves Mercury Toxicity in the Colon by Modulation of Oxidative Stress and Inflammation Through the Interplay of MAPK and NF-κB Signaling Cascades

Xinpeng Jiang, Shanshan Gu, Di Liu, Lili Zhao et al. • Frontiers in Microbiology (2018)

Aims:Lactobacillus strains have protective effects against heavy metals while relieving oxidative stress and modulating the immune response. Mechanisms that ameliorate heavy metal toxicity and the relationship between probiotics and gut bar...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2018.02425

Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells

Yuki Ota, Takuya Kawanai, Ryo Watanabe, Akira Nishimura et al. • Journal of Pharmacological Sciences (2013)

Abstract.: Nitric oxide (NO) induces cytotoxicity in neuronal and glial cells via activation of the Na+/Ca2+ exchanger (NCX). This study examined the role of the predominant brain-specific NCX splice variant NCX1.5 in NO-induced cytotoxicit...

DOAJ Open Access (DOAJ) DOI: 10.1254/jphs.13012SC