Academic Articles & Research Papers

Development of Rice Variety With Durable and Broad-Spectrum Resistance to Blast Disease Through Marker-Assisted Introduction of Pigm Gene

Rice blast, caused by Magnaporthe oryzae (M. oryzae), is one of the most destructive diseases threatening rice production worldwide. Development of resistant cultivars using broad-spectrum resistance (R) genes with high breeding value is th...

Two Novel ATP2C1 Mutations in Portuguese Patients with Hailey-Hailey Disease

Hailey-Hailey disease (HHD) is a rare autosomal dominant acantholytic dermatosis. It is characterized by a recurrent eruption of vesicles, erosions, and scaly erythematous plaques involving intertriginous areas and first occurring after pub...

First-Trimester Hematologic Inflammatory Markers and Pregnancy Loss in Women With Unexplained Recurrent Pregnancy Loss: A Retrospective Study of Associations and Discrimination.

Dizziness, Scanning Speech, and Transient Hyperreflexia as Atypical Initial Manifestations of Antiganglioside Q1b-Negative Miller Fisher Syndrome: A Case Report and Literature Review.

ScRNA-Seq Reveals Jiangfu Zhixie Formula Alleviates IBS-D by Inhibiting Macrophage M1 Polarization through HIF-1α-Glycolysis Axis.

Ethnic Differences in Clinical Manifestations of Behçet's Disease: A Retrospective Cohort Study of Turkic and Non-Turkic Patients.

Human RP105 monoclonal antibody enhances antigen-specific antibody production in unique culture conditions

Summary: Detecting antibodies, particularly those targeting donor human leukocyte antigens in organ transplantation and self-antigens in autoimmune diseases, is crucial for diagnosis and therapy. Radioprotective 105 (RP105), a Toll-like rec...

Under Pressure: Interactions between Commensal Microbiota and the Teleost Immune System

Commensal microorganisms inhabit every mucosal surface of teleost fish. At these surfaces, microorganisms directly and indirectly shape the teleost immune system. This review provides a comprehensive overview of how the microbiota and micro...

A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal calprotectin

Abstract Background Ankylosing spondylitis (AS) shares many characteristics with inflammatory bowel disease (IBD). Intestinal microbiota most likely plays an important role in the development of IBDs and may also be involved in the pathogen...

Interacting roles of gut microbiota and T cells in the development of autoimmune hepatitis

Autoimmune hepatitis (AIH) is a progressive liver inflammatory disease mediated by an autoimmune response, with an increasing incidence rate. In severe cases, AIH will rapidly progress to liver cirrhosis and liver failure and even lead to d...

Genetic Markers of Adaptation of <named-content content-type="genus-species">Plasmodium falciparum</named-content> to Transmission by American Vectors Identified in the Genomes of Parasites from Haiti and South America

ABSTRACT The malaria parasite, Plasmodium falciparum, was introduced into Hispaniola and other regions of the Americas through the slave trade spanning the 16th through the 19th centuries. During this period, more than 12 million Africans w...

Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure

Glaucoma is a leading cause of blindness, affecting up to 70 million people worldwide. High intraocular pressure (IOP) is a major risk factor for glaucoma. It is well established that inefficient aqueous humor (AqH) outflow resulting from s...

Personal Protective Equipment-Related Nasal Bridge Folliculitis in a Corona Warrior

Nasal bridge is a common site suffering personal protective equipment-induced skin damages over face among first-line health care workers in this coronavirus disease 2019 pandemic. We hereby report folliculitis as a complication following r...

Maternal cardiovascular adaptation to twin pregnancy: a population-based prospective cohort study

Abstract Background In women with singleton pregnancies, maternal adaptation is considered a stress test for later life cardiovascular disease. The aim of this study was to assess maternal adaptation in women with twin pregnancies compared ...

SHIFAYAAB – Centralized Platform for Vaccination Program

Vaccinations are very essential for the prevention of harmful diseases. However, the implementation rate of vaccination varies in different parts of the world. Many countries struggle to achieve the maximum immunization ratio due to their v...

Technology-Supported Behavior Change—Applying Design Thinking to mHealth Application Development

Non-communicable diseases are the leading cause of global deaths. The risk of their development and progression is increased by modifiable behavioral risk factors. Yet, despite the known benefits of primary and secondary prevention, people ...

Approaches, challenges, and recommendations for clinical practice in gestational syphilis: a scoping review

ABSTRACT Objective to map the scientific evidence on the approach to gestational syphilis, the sociodemographic profile of pregnant women, and the challenges related to its management and follow-up. Method scoping review carried out in Oc...

Identification and reporting of heart failure with preserved ejection fraction in Sub-Saharan Africa: a scoping review of diagnostic approaches, echocardiographic assessment, and evidence gaps

Abstract Background Heart failure with preserved ejection fraction (HFpEF) is increasingly recognized as a major heart failure phenotype globally; however, its diagnosis is complex and is recommended to require integrated assessment of clin...

The Effects of N-acetylcysteine on Inflammatory Markers and Homocysteine: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Background: Recently a number of trials investigated the effect of N-acetylcysteine (NAC) administration on inflammatory markers and homocysteine (Hcy). However, their findings are controversial. The aim of this paper is to present a meta-a...

QG-WRN: A Quantum-Enhanced Graph Convolutional Wide Residual Network for ASD Diagnosis via Neuroimaging Sensing Technology

The pathological mechanism of autism spectrum disorder (ASD) exhibits dual heterogeneity: abnormal local energy metabolism and brain-wide high-order topological failure. To synergistically characterize these complex signals captured by adva...