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Semi-rational design and modification of phosphoketolase to improve the yield of tyrosol in Saccharomyces cerevisiae

Na Song, Huili Xia, Yaoru Xie, Shuaikang Guo et al. • Synthetic and Systems Biotechnology (2025)

Tyrosol is an important component of pharmaceuticals, nutraceuticals, and cosmetics, and their biosynthetic pathways are currently a hot research topic. d-Erythrose 4-phosphate is a key precursor for the biosynthesis of tyrosol in Saccharom...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.synbio.2024.11.007

Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT

Kapil Sayal, Laura Wyatt, Louise Thomson, Grace Holt et al. • Health Technology Assessment (2025)

Background Emotional disorders are common in children and young people and can significantly impair their quality of life. Evidence-based treatments require a timely and appropriate diagnosis. The utility of standardised diagnostic assessme...

DOAJ Open Access (DOAJ) DOI: 10.3310/GJKS0519

Development of an evaluation framework for health information communication technology in contemporary pharmacy practice

Ayomide Ogundipe, Tin Fei Sim, Lynne Emmerton • Exploratory Research in Clinical and Social Pharmacy (2023)

Background: Health information communication technology (ICT) has rapidly evolved in contemporary pharmacy practice worldwide. The Australian healthcare system is experiencing a paradigm shift to real-time interconnectivity for practitioner...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rcsop.2023.100252

Health Technology and Reproduction

Kathleen M. Hoeger, Terhi Piltonen • Seminars in Reproductive Medicine (2024)

Kathleen M. Hoeger, MD, MPH Terhi T. Piltonen, MD, PhD The current issue of Seminars in Reproductive Medicine is devoted to a review of the burgeoning role of health technology in the field of reproductive medicine. The guest editor for the...

OPENALEX DOI: https://doi.org/10.1055/s-0044-1791777

Introduction to Health Technology Assessment

Vitantonio Di Bello, Gianni Tonti, Giuseppe Barletta, Giovanni Di Salvo et al. • Journal of Cardiovascular Echography (2012)

Abstract The objective of this review is to introduce the readers of this journal to the knowledge of some basic aspects of Health Technology Assessment (HTA). HTA starts from the need of the “political governance” to provide adequate healt...

OPENALEX DOI: https://doi.org/10.1016/j.jcecho.2012.05.002

Astaxanthin biofortification enhances tobacco tolerance to lead stress through boosting antioxidant defense, reducing Pb accumulation, and modulating detoxification pathways

Zhongyang Du, Mengjing Liang, Xiaodan Wang, Yizhen Liu et al. • Journal of Advanced Research (2026)

Introduction: Heavy metal pollution including lead (Pb) has become one of the serious global issues threatening food security, human health, and the ecosystem. Exogenous application of astaxanthin (ATX), a potent natural antioxidant, has be...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jare.2025.07.038

Development of an in vitro system to study oral biofilms in real time through impedance technology: validation and potential applications

Alex Mira, Elena Buetas, Bob T. Rosier, Danuta Mazurel et al. • Journal of Oral Microbiology (2019)

Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-...

DOAJ Open Access (DOAJ) DOI: 10.1080/20002297.2019.1609838

Anticancer and anti-angiogenic activities of mannooligosaccharides extracted from coconut meal on colorectal carcinoma cells in vitro

Patthra Pason, Chakrit Tachaapaikoon, Waralee Suyama, Rattiya Waeonukul et al. • Toxicology Reports (2024)

Colorectal carcinoma (CRC) is one of the most common malignancies, though there are no effective therapeutic regimens at present. This study aimed to investigate the inhibitory effects of mannooligosaccharides extracted from coconut meal (C...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2023.12.010

Effectiveness of Back care education Programme among school children: a systematic review of randomized controlled trials

Canice Chukwudi Anyachukwu, Confidence Chinemerem Amarah, Blessing Chiagozikam Atueyi, Ifeanyi Anthony et al. • BMC Pediatrics (2024)

Abstract Study design Systematic review of Randomised controlled trials. Objectives With the increasing incidence of back pain among children and its untold implications to their future, back education tailored in an effective way would be ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12887-024-04563-y

Strategy for health technology.

Sherry R. Arnstein • PubMed (1979)

This paper presents a conceptual framework for improved management to support a pilot demonstration for the U.S. Department of Health, Education, and Welfare's new Office of Health Technology, and reports findings and implications of a rece...

OPENALEX

Health technology, quality and safety in a learning health system

Elizabeth Marie Borycki, Andre William Kushniruk • Healthcare Management Forum (2022)

Health technology quality and safety is an important issue for health informatics (i.e. digital health) professionals. Health technologies have been used to (1) collect data that can be analyzed to improve the quality and safety of healthca...

OPENALEX cc-by-nc DOI: https://doi.org/10.1177/08404704221139383 PMC: 9975897

Barriers and facilitators to utilizing digital health technologies by healthcare professionals

Israel Júnior Borges do Nascimento, Hebatullah Mohamed Abdulazeem, Lenny Vasanthan, Edson Zangiacomí Martínez et al. • npj Digital Medicine (2023)

Abstract Digital technologies change the healthcare environment, with several studies suggesting barriers and facilitators to using digital interventions by healthcare professionals (HPs). We consolidated the evidence from existing systemat...

OPENALEX cc-by DOI: https://doi.org/10.1038/s41746-023-00899-4 PMC: 10507089

Health technology assessment: a framework

Manuela A. Joore, Sabine Elisabeth Grimm, Annelies E. R. C. H. Boonen, Maarten P. T. de Wit et al. • RMD Open (2020)

In a time where there is growing pressure on healthcare budgets, there is increased scrutiny of new health technologies, their effectiveness, safety and costs.1 It is in this context that Health Technology Assessment (HTA) has become increa...

OPENALEX cc-by-nc DOI: https://doi.org/10.1136/rmdopen-2020-001289 PMC: 7856136

The Impact of Bio-Based Fertilizer Integration Into Conventional Grassland Fertilization Programmes on Soil Bacterial, Fungal, and Nematode Communities

Demi Ryan, Anna Karpinska, Patrick J. Forrestal, S. M. Ashekuzzaman et al. • Frontiers in Sustainable Food Systems (2022)

Phosphorus (P) is an essential plant macro-nutrient applied to soil in agriculture, mainly sourced from non-renewable mined phosphate-rock, of which readily accessible reserves are currently under pressure, while global food demand continue...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsufs.2022.832841

The effects of women's empowerment on the nutritional status of children in Nigeria using the 2018 demographic health survey

Ademola Akinlade, Mercy Olateju, Mayowa Salami, Oluwaseyifunmi Akinlade et al. • Babcock University Medical Journal (2026)

Objectives: The empowerment of women critically influences child nutrition in Nigeria, where malnutrition remains a major public health challenge. This study examines the relationship between dimensions of women’s empowerment, economic, edu...

DOAJ Open Access (DOAJ) DOI: 10.38029/babcockuniv.med.j..v9i3.1114

[Health technology in Mexico].

C Cruz, Gladys Faba, Jaime Martuscelli • PubMed (1992)

The features of the health technology cycle are presented, and the effects of the demographic, epidemiologic and economic transition on the health technology demand in Mexico are discussed. The main problems of science and technology in the...

OPENALEX

User-Centered Design and Interactive Health Technologies for Patients

Annette De Vito Dabbs, Brad A. Myers, KENNETH R. MC CURRY, Jacqueline M. Dunbar‐Jacob et al. • CIN Computers Informatics Nursing (2009)

Despite recommendations that patients be involved in the design and testing of health technologies, few reports describe how to involve patients in systematic and meaningful ways to ensure that applications are customized to meet their need...

OPENALEX Open Access DOI: https://doi.org/10.1097/ncn.0b013e31819f7c7c PMC: 2818536

The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B

Shi-Long Jiang, Shi-Long Jiang, Zhi-Bin Wang, Zhi-Bin Wang et al. • Frontiers in Pharmacology (2021)

Vemurafenib, a BRAF V600E inhibitor, provides therapeutic benefits for patients with melanoma, but the frequent emergence of drug resistance remains a challenge. An understanding of the mechanisms underlying vemurafenib resistance may gener...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2021.720619