Academic Articles & Research Papers

International practices in health technology assessment and public financing of digital health technologies: recommendations for Hungary

Background: Evaluating and integrating digital health technologies is a critical component of a national healthcare ecosystem in the 2020s and is expected to even increase in significance. Design: The paper gives an overview of internationa...

Health technology and knowledge

Global Health Technology 2.0

Collaborative approach for global health technology is reported. The Global Health Initiative (GHI) at the Center for Integration of Medicine and Innovative Technology, the Center for Global Health at Massachusetts General Hospital (MGH), a...

HEALTH TECHNOLOGY ASSESSMENT IN CANADA

OBJECTIVES: Since 1988, four government-funded health technology assessment (HTA) agencies have been established in Canada. This paper is a descriptive review of reports issued by these organizations during the period from 1988 to 1998. MET...

Methods for Population-Adjusted Indirect Comparisons in Health Technology Appraisal

Standard methods for indirect comparisons and network meta-analysis are based on aggregate data, with the key assumption that there is no difference between the trials in the distribution of effect-modifying variables. Methods which relax t...

Health technology assessment: the journey continues

Perrin Beatty, Canadian minister of health and welfare, 1989–1991, said that Canada needs “a more coordinated approach across the country to ensure that all Canadians are benefiting from the advances being made in health technology.” These ...

Evaluation of Blood-Based Antibody Rapid Testing for HIV Early Therapy: A Meta-Analysis of the Evidence

BackgroundWestern blot (WB) assay is considered the gold standard test for HIV infection confirmation. However, it requires technical expertise and is quite time-consuming. WHO recommends blood-based rapid diagnosis to achieve same-day test...

Methods for studying health disparities in U.S. nursing homes: a scoping review

Abstract Background Health disparities exist across healthcare settings, including nursing homes, contributing to preventable differences in care quality. Health disparities are a global issue, yet most studies on nursing home health dispar...

Alleviating D-Galactose-Induced Aging in Mice by Modulating Gut-Liver Axis Using <i>Lactiplantibacillus plantarum</i> TY-Y10

Oxidative stress is closely linked to aging. Probiotics, whether viable or heat-inactivated, have shown antioxidant properties; however, their effect and mechanism of action in reducing oxidative stress during aging remains underexplored. T...

Barriers and facilitators of retention in care after cervical cancer screening: patients’ and healthcare providers’ perspectives

Abstract Background Cervical cancer continues to threaten women’s health, especially in low-resource settings. Regular follow-up after screening and treatment is an effective strategy for monitoring treatment outcomes. Consequently, underst...

Muscle Bmal1 is Dispensable for the Progress of Neurogenic Muscle Atrophy in Mice

Global deletion of aryl hydrocarbon receptor nuclear translocator-like ('Arntl'; also known as 'Bmal1'), a molecular component of the circadian clock, resulted in an extreme loss of muscle mass. However, the functional role of muscle BMAL1 ...

Analysis of TORCH screening and prenatal risk assessment for childbearing-age women in different regions of China

Abstract Objective By conducting TORCH screening and risk assessment analysis on childbearing-age women in different regions of China, the aim is to provide reference for reducing adverse pregnancy outcomes and improving the health status o...

A hybrid plasmid formed by recombination of a virulence plasmid and a resistance plasmid in Klebsiella pneumoniae

Objective: The emergence of multidrug-resistant (MDR) and hypervirulent Klebsiella pneumoniae (hvKP) facilitates simultaneous dissemination of virulence and resistance in a single event, which poses serious threat to public health. Methods:...

Predictive Value of Serum Cytokeratin 19 Level for the Feasibility of Conserving Ovaries in Endometrial Cancer

Objective: To determine the predictive value of cytokeratin 19 (CK19) for evaluating the safety of ovarian preservation in patients with endometrial cancer (EC).Methods: Five hundred and seventeen EC patients hospitalized from November 2010...

Nutritional knowledge, attitudes and behaviours in rugby league; influences of age, body composition and ancestry

Introduction Rugby league is a physically demanding sport that necessitates considerable nutritional intake, focusing on quality and type, in order to optimize training and competition demands. However, rugby league athletes are reported to...

Multimodal Physical Therapy Management of Dysmenorrhea With Coexisting Mechanical Low Back Pain and Early Degenerative Lumbar Spondylosis: A Case Report

ABSTRACT A 21‐year‐old woman with dysmenorrhea, mechanical low back pain, early lumbar spondylosis, heavy menstrual bleeding, and anemia received 4 weeks of multimodal physiotherapy. Pain and function improved, but heavy bleeding created di...

Further validation of the Chinese short Warwick Edinburgh mental wellbeing scale in the adult population of Macau: an application of classic test theory and item response theory

BackgroundThis study aims to validate the Chinese version of the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) by employing both Classical Test Theory (CTT) and Item Response Theory (IRT) approaches.MethodsData were gathered thr...

Systems Thinking in Health Technology

Health Technology Assessment in Health-Care Decisions in the United States

Wearable Digital Health Technology