Academic Articles & Research Papers

Mobile health approaches to disease surveillance in Africa; Wellvis COVID triage tool

COVID-19 has rapidly spread across the globe and was declared a pandemic by the World Health Organization (WHO). The COVID-19 infection continues to spread across Africa. In Africa, mobile phone applications have been used for the surveilla...

Challenges and conditions for successfully implementing and adopting the telematics infrastructure in German outpatient healthcare: A qualitative study applying the NASSS framework

Background Germany's healthcare system provides high-quality, universal health coverage to almost all residents. However, a major challenge lies in the strong separation of healthcare structures, which hinders efficient interprofessional an...

Medical Informatics

Optimal@NRW: optimized acute care of nursing home residents using an intersectoral telemedical cooperation network — study protocol for a stepped-wedge trial

Abstract Background Increasing life expectancy is associated with a growing number of people living in nursing homes, while the availability of outpatient medical care, especially from family doctors, is stagnating in this sector. Consequen...

Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial

BackgroundWeight loss is a cornerstone of obesity treatment and diabetes mellitus type 2 (T2D) prevention, but its implementation in clinical practice is limited by its perceived burden and variability in response. Personalizing interventio...

Structural dataset for the PPARγ V290M mutant

Loss-of-function mutation V290M in the ligand-binding domain of the peroxisome proliferator activated receptor γ (PPARγ) is associated with a ligand resistance syndrome (PLRS), characterized by partial lipodystrophy and severe insulin resis...

The Role of iSchools in Medical Informatics

Similar to iSchools, healthcare is an interdisciplinary field that encompasses heterogeneous environments (e.g., hospitals, clinics, home) and perspectives. However, medical informatics research focuses mainly on technical solutions to narr...

Medical Informatics and Opportunity for Anesthesiologists.

This is the fifth year that we are organizing the anesthesia symposium/debate during the annual meeting of the Chinese Society of Anesthesiologists. The member of the symposium consists a team from China lead by Dr. Buwei Yu, the immediate ...

Fifty years in medical informatics.

OBJECTIVES: An overview of personal experiences in medical informatics based on Dr. Morris Collen's 50 years of research in the field. METHODS: A personal reminiscence and historical overview, focusing on the first two decades of medical in...

Dataset for the dimethyl sulfoxide as a novel thermodynamic inhibitor of carbon dioxide hydrate formation

The temperatures and pressures of the three-phase equilibrium V-Lw-H (gas – aqueous solution – gas hydrate) were measured in the CO2 – H2O – dimethyl sulfoxide (DMSO) system at concentrations of organic solute in the aqueous phase up to 50 ...

Classroom Management Strategies of Multigrade Schools with Emphasis on the Role of Technology

Introduction : It appears that the effectiveness of a multigrade school class is dependent on the type of class management. Therefore this study aims to determine the classroom management strategies in multigrade schools with emphasis on th...

Implementing and Evaluating a National Integrated Digital Registry and Clinical Decision Support System in Early Intervention in Psychosis Services (Early Psychosis Informatics Into Care): Co-Designed Protocol

BackgroundEarly intervention in psychosis (EIP) services are nationally mandated in England to provide multidisciplinary care to people experiencing first-episode psychosis, which disproportionately affects deprived and ethnic minority yout...

COVID-19: Detecting depression signals during stay-at-home period

The new coronavirus outbreak has been officially declared a global pandemic by the World Health Organization. To grapple with the rapid spread of this ongoing pandemic, most countries have banned indoor and outdoor gatherings and ordered th...

A method for automatically extracting infectious disease-related primers and probes from the literature

Abstract Background Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the diagnosis and prescription of infectious diseases. Th...

Behind the scars: adolescents with non-suicidal self-injury disorder show profound personality pathology

Abstract Background Non-suicidal self-injury is a significant clinical concern in adolescent psychiatry and frequently co-occurs with a range of psychiatric disorders, including mood disorders, eating disorders, substance use disorders, and...

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy

Excessive activation of inflammatory signaling pathways seems to be a hallmark of epileptogenesis. Positron emission tomography (PET) allows in vivo detection of brain inflammation with spatial information and opportunities for longitudinal...

Identifying peer experts in online health forums

Abstract Background Online health forums have become increasingly popular over the past several years. They provide members with a platform to network with peers and share information, experiential advice, and support. Among the members of ...

Ten Topics for Medical Informatics

A living, curated collection of key topics and in-depth literature to get started in Medical Informatics research, extending the viewpoint article "Ten Topics to Get Started in Medical Informatics Research"....

A genome-wide association study on meat consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort study

Recent genome-wide association studies (GWAS) on the dietary habits of the Japanese population have shown that an effect rs671 allele was inversely associated with fish consumption, whereas it was directly associated with coffee consumption...

In silico analysis of ciprofloxacin analogs as inhibitors of DNA gyrase of Staphylococcus aureus

In this in silico study, thirty-five ciprofloxacin analogs were docked to the active site of DNA gyrase, the prime target of ciprofloxacin type antibiotics. Prior to docking all the structures were optimized using MM2 force field parameters...