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Mangifera Indica leaf extracts promote hair growth via activation of Wnt signaling pathway in human dermal papilla cells

Haesoo Jung, Da-Min Jung, Sang-Soo Lee, Eun-Mi Kim et al. • Animal Cells and Systems (2022)

The crosstalk between androgens and Wnt signaling pathways is critical in the hair growth cycle. Therefore, natural products that target these two pathways for the inhibition of hair loss are sought after. In this study, we investigated the...

DOAJ Open Access (DOAJ) DOI: 10.1080/19768354.2022.2085790

Altered Red Blood Cell Fatty Acid and Serum Adipokine Profiles in Subjects with Obesity

Asier Léniz, Alfredo Fernández-Quintela, Sara Arranz, Kevin Portune et al. • Biomedicines (2023)

Background: Adipokines, as well as the fatty acid profile of red blood cell (RBC) membranes, are known to play important roles in the development and progression of metabolic complications induced by obesity. Thus, the objective of this stu...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines11123320

Effects on Dopaminergic Neurons Are Secondary in COX-Deficient Locomotor Dysfunction in Drosophila

Cagri Yalgin, Bohdana Rovenko, Ana Andjelković, Margot Neefjes et al. • iScience (2020)

Summary: Dopaminergic (DA) neurons have been implicated as key targets in neurological disorders, notably those involving locomotor impairment, and are considered to be highly vulnerable to mitochondrial dysfunction, a common feature of suc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.isci.2020.101362

HEALTH TECHNOLOGY REASSESSMENT: THE ART OF THE POSSIBLE

Gail MacKean, Tom Noseworthy, Adam G. Elshaug, Laura E. Leggett et al. • International Journal of Technology Assessment in Health Care (2013)

BACKGROUND: Health technology reassessment (HTR) is "a structured, evidence-based assessment of the clinical, social, ethical, and economic effects of a technology currently used in the healthcare system, to inform optimal use of that techn...

OPENALEX cc-by-nc-sa DOI: https://doi.org/10.1017/s0266462313000494 PMC: 3846380

Health technology assessment in Canada

Renaldo N. Battista, Brigitte Côté, Matthew J. Hodge, Don Husereau • International Journal of Technology Assessment in Health Care (2009)

Canada's health system is a unique combination of public financing and private provision. With the significant government role in financing health services, health technology assessment (HTA) has found a ready audience as a form of policy r...

OPENALEX Open Access DOI: https://doi.org/10.1017/s0266462309090424

Health technology assessment to optimize health technology utilization: Using implementation initiatives and monitoring processes

Katrine Bjørnebek Frønsdal, Karen M. Facey, Marianne Klemp, Inger Natvig Norderhaug et al. • International Journal of Technology Assessment in Health Care (2010)

BACKGROUND: The way in which a health technology is used in any particular health system depends on the decisions and actions of a variety of stakeholders, the local culture, and context. In 2009, the HTAi Policy Forum considered how health...

OPENALEX Open Access DOI: https://doi.org/10.1017/s0266462310000309

Conserved lipid-facing basic residues promote the insertion of the porin OmpC into the E. coli outer membrane

Janine H. Peterson, Lixinhao Yang, James C. Gumbart, Harris D. Bernstein • mBio (2025)

ABSTRACT Almost all integral membrane proteins that reside in the outer membrane (OM) of gram-negative bacteria contain a closed amphipathic β sheet (“β barrel”) that serves as a membrane anchor. The membrane integration of β barrel structu...

DOAJ Open Access (DOAJ) DOI: 10.1128/mbio.03319-24

Green synthesis and characterization of silver nanoparticles through the Piper cubeba ethanolic extract and their enzyme inhibitory activities

Khalil Ahmad, Hafiz Muhammad Asif, Taimoor Afzal, Mohsin Abbas Khan et al. • Frontiers in Chemistry (2023)

Introduction: The area of “Green Synthesis of Nano-medicine,” as compared to its synthetic counterparts, is a relatively safer research technology for various biomedical applications, including identification, therapeutic application, and p...

DOAJ Open Access (DOAJ) DOI: 10.3389/fchem.2023.1065986

Evidence Center structural and operational conditions and challenges: a descriptive study, Brazil, 2024

Y. Juliana Cardozo Amaya, Pedro Henrique Alves Santos, Aurelina Aguiar Lima, Camila Lasse Silva et al. • Epidemiologia e Serviços de Saúde (2026)

Abstract Objective: To describe the physical, structural and operational conditions, as well as the main challenges faced by Evidence Centers (NEvs) recognized by the Evidence-Informed Policy Network (EVIPNet) Brazil. Methods: This is a...

DOAJ Open Access (DOAJ) DOI: 10.1590/s2237-96222026v35e20250457.en

Change in lifestyle with health technology

Sachin K. Parappagoudar, Sana Saima, K Haneesha, Chavi Jain et al. • International Journal of Research in Management (2023)

To preserve excellent health and prevent chronic diseases, one must adopt a healthy lifestyle. Yet, altering one's way of life can be difficult, particularly without the necessary resources and assistance. Luckily, new opportunities to enco...

OPENALEX Open Access DOI: https://doi.org/10.33545/26648792.2023.v5.i1a.67

Distributed Bragg reflectors for the colorimetric detection of bacterial contaminants and pollutants for food quality control

Giuseppe M. Paternò, Giovanni Manfredi, Francesco Scotognella, Guglielmo Lanzani • APL Photonics (2020)

Real-time monitoring of bacterial contaminants and pollutants in food is of paramount importance nowadays, owing to the impressive extension of the food production/supply chain and the consequent increase in foodborne outbreaks worldwide. T...

DOAJ Open Access (DOAJ) DOI: 10.1063/5.0013516

Developing New Health Material: The Utilization of Spray Drying Technology on Avocado (<i>Persea Americana</i> Mill.) Seed Powder

Karen Alissa, Yu-Chi Hung, Chih Yao Hou, GiGi Chin Wen Lim et al. • Foods (2020)

Avocado (Persea Americana Mill.) generates byproducts, especially the avocado seeds. Hence, the aim of this study was to investigate the potential utilization of avocado seed as a very important, high phenolic content, climacteric fruit wit...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods9020139

Chemometric Analysis of Serum Magnesium Calculations Using Mg-Xylidyl Blue-I Method Based on Molar Absorptivity

Ally Kafesa, Nadira Nur Hajah Lutfi, Cep Wahyu • Indonesian Journal of Medical Laboratory Science and Technology (2021)

The concentration of magnesium is determined based on the absorbance of the Mg-Xylydil Blue-I complex solution use spectrophotometer. Based on the Lambert-Beer rule, the calculation of sample concentration is based on the formula A = Ԑ. b. ...

DOAJ Open Access (DOAJ) DOI: 10.33086/ijmlst.v3i1.1876

Cost-Effectiveness Analysis of Pan-Genotypic Sofosbuvir-Based Regimens for Treatment of Chronic Hepatitis C Genotype 1 Infection in China

Hui Jun Zhou, Jing Cao, Hui Shi, Nasheen Naidoo et al. • Frontiers in Public Health (2021)

Background: Hepatitis C virus (HCV) genotype 1 is the most prevalent HCV infection in China. Sofosbuvir-based direct antiviral agent (DAA) regimens are the current mainstays of treatment. Sofosbuvir/velpatasvir (SOF/VEL) and sofosbuvir/ledi...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2021.779215

Combination of Antimicrobial Starters for Feed Fermentation: Influence on Piglet Feces Microbiota and Health and Growth Performance, Including Mycotoxin Biotransformation in vivo

Laurynas Vadopalas, Modestas Ruzauskas, Modestas Ruzauskas, Vita Lele et al. • Frontiers in Veterinary Science (2020)

The aim of this study was to apply a combination of the microbial starters Lactobacillus uvarum LUHS245, Lactobacillus casei LUHS210, Pediococcus acidilactici LUHS29, and Pediococcus pentosaceus LUHS183 for feed fermentation and to evaluate...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2020.528990

International diffusion of new health technologies: A ten-country analysis of six health technologies

Claire Packer, Sue Simpson, Andrew J Stevens, (on behalf of EuroScan: the European Information Network on New and Changing Health Technologies) • International Journal of Technology Assessment in Health Care (2006)

OBJECTIVES: The objective of this study was to examine and explain the differential international diffusion of six health innovations. METHODS: A retrospective diffusion study was undertaken of sildenafil, cyclooxygenase-II (COX II) inhibit...

OPENALEX DOI: https://doi.org/10.1017/s0266462306051336

Health technology assessment in Italy

Carlo Favaretti, Americo Cicchetti, Giovanni Maria Guarrera, Marco Marchetti et al. • International Journal of Technology Assessment in Health Care (2009)

OBJECTIVES: The aim of this study was to review the history of health technology assessment (HTA) in Italy. METHODS: Founded in 1978, the Italian National Health Service (NHS) has been strongly regionalized mainly after a constitutional ref...

OPENALEX Open Access DOI: https://doi.org/10.1017/s0266462309090539

Advances in High Throughput Proteomics Profiling in Establishing Potential Biomarkers for Gastrointestinal Cancer

Md Zahirul Islam Khan, Shing Yau Tam, Helen Ka Wai Law • Cells (2022)

Gastrointestinal cancers (GICs) remain the most diagnosed cancers and accounted for the highest cancer-related death globally. The prognosis and treatment outcomes of many GICs are poor because most of the cases are diagnosed in advanced me...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells11060973