Academic Articles & Research Papers

Preclinical ex-vivo Testing of Anti-inflammatory Drugs in a Bovine Intervertebral Degenerative Disc Model

Discogenic low back pain (LBP) is a main cause of disability and inflammation is presumed to be a major driver of symptomatic intervertebral disc degeneration (IDD). Anti-inflammatory agents are currently under investigation as they demonst...

Genetic Manipulation of Plants: A More-than-Human Ethical Challenge

The central argument of this article is that the genetic manipulation of plants raises profound ethical questions that cannot be adequately addressed within a purely anthropocentric framework. Drawing on Hans Jonas’s philosophy of responsib...

A call for congressional action: revisiting the U.S. coordinated framework for the regulation of biotechnology

Since the 1986 release of the Coordinated Framework for the Regulation of Biotechnology almost 40 years ago, there have been two whole of government updates that made only minor changes, while new regulations and guidance from individual ag...

Functionalising Collagen-Based Scaffolds With Platelet-Rich Plasma for Enhanced Skin Wound Healing Potential

Porous collagen-glycosaminoglycan (collagen-GAG) scaffolds have shown promising clinical results for wound healing; however, these scaffolds do not replace the dermal and epidermal layer simultaneously and rely on local endogenous signaling...

Cell-Based Sensors for the Detection of EGF and EGF-Stimulated Ca²⁺ Signaling

Epidermal growth factor (EGF)-mediated activation of EGF receptors (EGFRs) has become an important target in drug development due to the implication of EGFR-mediated cellular signaling in cancer development. While various in vitro approache...

Lightweight geo-bead fill to prevent soft ground deposit failure

As a foundation for transportation infrastructure, soft ground has limited bearing capacity and high compression. To prevent embankment failure, lightweight material is suggested. In the construction of road embankments, EPS can be regarded...

A Novel Combining Method for Composite Groove Structure Fabrication

A composite groove structure with high specific strength and light weight has great potential in industrial application, but few studies on this have been carried out due to the fact that it is difficult to fabricate by one of the existing ...

The detection of trans gene fragments of hEPO in gene doping model mice by Taqman qPCR assay

Background With the rapid progress of genetic engineering and gene therapy methods, the World Anti-Doping Agency has raised concerns regarding gene doping, which is prohibited in sports. However, there is no standard method available for de...

Analysis of the status and framework design of intelligentcoal mine auxiliary transportation system

This paper introduces the development and application status of intelligent auxiliary transportation technology in open-pit coal mine and underground coal mines at home and abroad. The intelligent auxiliary transportation system of open-pit...

Physicochemical- and biocompatibility of oxygen and nitrogen plasma treatment using a PLA scaffold

Plasma surface treatment has a wide range of applications in biomedicine. In the present study, flat polylactic acid (PLA) films were treated with oxygen and nitrogen, low-pressure, non-thermal plasma. The water contact angle of the PLA fil...

Resting-state EEG measures cognitive impairment in Parkinson’s disease

Abstract Cognitive dysfunction is common in Parkinson’s disease (PD). We developed and evaluated an EEG-based biomarker to index cognitive functions in PD from a few minutes of resting-state EEG. We hypothesized that synchronous changes in ...

ABCD: advanced blockchain DSR algorithm for MANET to mitigate the different security threats

Abstract Mobile ad hoc networks (MANETs) facilitate data communication across multiple nodes and hop stations, characterized by their dynamic topology. This inherent flexibility, however, makes MANETs vulnerable to various security threats,...

Towards the technological maturity of membrane distillation: the MD module performance curve

Abstract Membrane distillation (MD) is constantly acknowledged in the research literature as a promising technology for the future of desalination, with an increasing number of studies reported year after year. However, real MD applications...

Case reports of latent HBV hepatitis in patients after neurosurgical treatment for hypothalamic and pituitary tumors

Abstract Background Hepatitis B virus (HBV) infection is a major public health problem worldwide. More than 2 billion people have been exposed to HBV, and about 257 million individuals are chronic carriers of HBV. HBV reactivation has been ...

Nonverbal competence in researching the communicative and organizational skills of teachers /Competența nonverbală în cercetarea aptitudinilor comunicative şi organizatorice a cadrelor didactice

Arising from the complexity and multidisciplinarity of the problem of nonverbal communication and impression management in the organizational environment, its investigation constitutes a common subject for several sciences, being located at...

Quenching factors for Na recoils as a function of Tl dopant concentrations in NaI(Tl) crystals

Abstract Thallium-doped sodium iodide (NaI(Tl)) scintillation detectors play an important role in the field of direct dark matter (DM) searches. The DAMA/LIBRA experiment stands out for its reported observation of an annually modulating DM-...

Research on the Longitudinal Section of River Restoration Using Probabilistic Theory

Since the 1960s, many rivers have been destroyed as a consequence of the process of rapid urbanization. As accurate figures are important to repair rivers, there have been many research reports on methods to obtain the exact river slope and...

Entropy in Brain Networks

A thorough and comprehensive understanding of the human brain ultimately depends on knowledge of large-scale brain organization[...]...

Erratum to: Search for resonant and nonresonant production of pairs of dijet resonances in proton-proton collisions at s $$ \sqrt{s} $$ = 13 TeV

Genetic Algorithms in Astronomy and Astrophysics

This paper aims at demonstrating, through examples, the applicability of genetic algorithms to wide classes of problems encountered in astronomy and astrophysics. Genetic algorithms are heuristic search techniques that incorporate, in a com...