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Academic Articles & Research Papers
Showing 20 of 4,355 academic articles
Qinghua Luo, Xintan Dong, Zhaxi Zerang, Yujiao Chen et al. • Cell Reports
(2026)
Summary: The β-barrel assembly machinery (BAM) is essential for outer membrane protein (OMP) biogenesis in Gram-negative bacteria and represents a validated target for antibiotic development. Its evolutionary relative, the translocation and...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.celrep.2026.117733
Martin Sindelar, Anna Kocurkova, Matej Simek, Pavel Roudnicky et al. • MicrobiologyOpen
(2026)
ABSTRACT The ability of gut microbes to degrade host‐ and diet‐derived glycans is central to microbiome ecology and host interactions, yet predicting these functions in silico remains challenging. Hyaluronan (HA), a glycosaminoglycan (GAG) ...
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Open Access (DOAJ)
DOI: 10.1002/mbo3.70227
Khushboo Singh, Roon Banerjee, Chandrakanta Potdar, Anisha Shaw et al. • Cells
(2026)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are among the most common genetic causes of Parkinson’s disease (PD), yet substantial heterogeneity exists among pathogenic variants. How mutations in distinct functional domains of LRRK2 di...
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Open Access (DOAJ)
DOI: 10.3390/cells15040342
Victoria Vitkova, Vesela Yordanova, Galya Staneva, Ognyan Petkov et al. • Membranes
(2021)
Simple carbohydrates are associated with the enhanced risk of cardiovascular disease and adverse changes in lipoproteins in the organism. Conversely, sugars are known to exert a stabilizing effect on biological membranes, and this effect is...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/membranes11110847
Ali Aytac Seymen, Ezgi Gulten, Erol Ozgur, Bülend Ortaç et al. • Scientific Reports
(2023)
Abstract Coronavirus Disease-19 (COVID-19) is a highly contagious infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The development of rapid antigen tests has contributed to easing the burden on ...
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Open Access (DOAJ)
DOI: 10.1038/s41598-023-31177-8
Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares et al. • Molecules
(2021)
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...
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Open Access (DOAJ)
DOI: 10.3390/molecules26226923
Maria Angelova, Petko Alov, Ivanka Tsakovska, Dessislava Jereva et al. • Molecules
(2025)
Scoring functions are key elements in docking protocols as they approximate the binding affinity of a ligand (usually a small bioactive molecule) by calculating its interaction energy with a biomacromolecule (usually a protein). In this stu...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules30132777
Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang et al. • Journal of Translational Medicine
(2024)
Abstract Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-deri...
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Open Access (DOAJ)
DOI: 10.1186/s12967-024-05257-w
Balamurugan Jagadeesan, Leen Baert, Martin Wiedmann, Renato H. Orsi • Frontiers in Microbiology
(2019)
As WGS is increasingly used by food industry to characterize pathogen isolates, users are challenged by the variety of analysis approaches available, ranging from methods that require extensive bioinformatics expertise to commercial softwar...
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Open Access (DOAJ)
DOI: 10.3389/fmicb.2019.00947
Serap Süzük Yıldız, Ayşegül Polat, Süleyman Yalçın, Mert Emre Ölmez et al. • Journal of Infection in Developing Countries
(2025)
Introduction: Most of Bacillus spp. generally avirulent species in healthy patients, but if there is a fragile in the patient, especially their immune system, Bacillus spp. can be an agent for infections.
Case Report: In this case, we rep...
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Open Access (DOAJ)
DOI: 10.3855/jidc.20080
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok • Фармакоэкономика
(2025)
Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect ...
DOAJ
Open Access (DOAJ)
DOI: 10.17749/2070-4909/farmakoekonomika.2024.285
Bruna Scalia, Marco Andrea Nicola Saporito, Laura Mauceri, Alessandro Valerio Saporito et al. • Italian Journal of Pediatrics
(2024)
Abstract Background SARS-CoV-2’s potential consequences on the developing brain are still unknown. The aim of this study was to describe cranial ultrasonographic (cUS) findings in a population of newborns exposed to SARS-CoV-2 born at San M...
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Open Access (DOAJ)
DOI: 10.1186/s13052-024-01826-3
Shermineh Heydari, Ladan Kashani, Mehrdad Noruzinia • Iranian Journal of Allergy, Asthma and Immunology
(2021)
Endometriosis is a common, chronic, inflammatory disorder in women, characterized by the presence of endometrial tissue outside the uterus cavity. The disease affects ~10% of women during their reproductive age. There is some debates on the...
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Open Access (DOAJ)
Brianna Dufek, Daniel T Meehan, Duane Delimont, Kevin Wilhelm et al. • PLoS ONE
(2020)
Previous work demonstrates that the hearing loss in Alport mice is caused by defects in the stria vascularis. As the animals age, progressive thickening of strial capillary basement membranes (SCBMs) occurs associated with elevated levels o...
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Open Access (DOAJ)
DOI: 10.1371/journal.pone.0237907
Jing Yang, Pengfei Li, Pengfei Li, Pengfei Li et al. • Frontiers in Immunology
(2022)
ObjectiveExtranodal natural killer/T cell lymphoma (NKTCL) is an aggressive EBV-related lymphoma, originating from NK cells or T cells. Previous study demonstrated that CD56 negative NKTCL should be recognized as a distinct subtype. In this...
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Open Access (DOAJ)
DOI: 10.3389/fimmu.2022.829366
Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports
(2025)
Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...
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Open Access (DOAJ)
DOI: 10.1038/s41598-025-32406-y
Lin J, Xue Y, Su W, Zhang Z et al. • International Journal of COPD
(2022)
Jie Lin,1,2,* Yanlong Xue,1,2,* Wenyan Su,1,2,* Zan Zhang,1,2 Qiu Wei,1,2 Tianxia Huang1,2 1Department of Respiratory and Critical Care, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530022, Peop...
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Open Access (DOAJ)
Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao et al. • PeerJ
(2020)
Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophy...
DOAJ
Open Access (DOAJ)
DOI: 10.7717/peerj.9796
Rita Patrizia Aquino, Teresa Mencherini, Pierluigi Mazzei, Tiziana Esposito et al. • Carbohydrate Polymer Technologies and Applications
(2025)
This study reports on the development of a carbohydrate-based spray-dried microparticulate system (F-CHES) conceived for the stabilization and foliar delivery of polyphenol-rich plant extracts for sustainable phyto defense applications. Che...
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Open Access (DOAJ)
DOI: 10.1016/j.carpta.2025.101023
Chao Ren, Peiyuan Yin, Neng Ren, Zhe Wang et al. • Stem Cell Research & Therapy
(2018)
Abstract Recent studies have suggested that the regulation of endogenous neural stem cells (NSCs) or transplanting of exogenous nerve cells are the newest and most promising methods for the treatment of dementia and other neurological disea...
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Open Access (DOAJ)
DOI: 10.1186/s13287-018-0807-3