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UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking

Shijiao Zhang, Yanding Su, Ao Han, He Qi et al. • Pharmaceuticals (2025)

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph18081111

From plants to patterns: Constructing a comprehensive online strontium isoscape for Belgium (IsoBel) using high density grid mapping

Amanda Sengeløv, Giacomo Capuzzo, Sarah Dalle, Hannah F. James et al. • Geoderma (2025)

Understanding the spatial distribution of strontium isotopes in plants or other archives within a region is crucial for various fields, including archaeology, environmental studies, food sciences and forensic science. This study aims to cre...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.geoderma.2024.117123

Impact of <i>Chlorella vulgaris</i> Bioremediation and Selenium on Genotoxicity, Nephrotoxicity and Oxidative/Antioxidant Imbalance Induced by Polystyrene Nanoplastics in African Catfish (<i>Clarias gariepinus</i>)

Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes (2024)

Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...

DOAJ Open Access (DOAJ) DOI: 10.3390/fishes9020076

Some conceptual aspect of overcoming anti-detection and investigation of crimes

G.V. Burganova, R.R. Rahmatullin • Ученые записки Казанского университета: Серия Гуманитарные науки (2019)

The paper considers the problem of the concept and signs of counteraction to the investigation of crimes. The positions of various legal scholars of the conceptual apparatus of counteraction have been analyzed in detail. The definition of c...

DOAJ Open Access (DOAJ) DOI: 10.26907/2541-7738.2019.1.169-181

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24

Analysis of the ex-vivo transformation of semen, saliva and urine as they dry out using ATR-FTIR spectroscopy and chemometric approach

Tanurup Das, Abhimanyu Harshey, Ankit Srivastava, Kriti Nigam et al. • Scientific Reports (2021)

Abstract The ex-vivo biochemical changes of different body fluids also referred as aging of fluids are potential marker for the estimation of Time since deposition. Infrared spectroscopy has great potential to reveal the biochemical changes...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-91009-5

A sustainable supramolecular deep eutectic solvent system for dispersive liquid–liquid microextraction followed by HPLC for the determination of melamine in milk samples

Modar Sadek, Nazira Sarkis, George Jangi • Results in Chemistry (2026)

This work presents the development and application of an innovative green supramolecular deep eutectic solvent (SUPRADES)-based DLLME approach for the extraction and quantification of melamine in milk matrices. For this purpose, thymol and ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rechem.2026.103057

Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Christian G. Ziegler, Carina Riediger, Matthias Gruber, Carola Kunath et al. • Frontiers in Endocrinology (2022)

Pheochromocytomas (PCCs) are rare but potentially lethal tumors that arise from the adrenal medulla. The clinical suspicion and diagnosis of PCC can be challenging due to the non-specific nature of signs and symptoms. In many patients, infe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2022.967995

Anti-inflammatory activity of two varieties of pumpkin seed oil in an adjuvant arthritis model in rats

S. Y. Al-Okbi, D. A. Mohamed, E. Kandil, M. A. Abo-Zeid et al. • Grasas y Aceites (2017)

The aim of the present research was to evaluate the anti-inflammatory activity of pumpkin seed oils (PSOs) of an Egyptian and European variety, in a rat model of adjuvant arthritis. Edema thickness, plasma tumor necrosis factor-α (TNF-α) an...

DOAJ Open Access (DOAJ) DOI: 10.3989/gya.0796161

What motivates SARS-CoV-2 vaccine trial participants? A pre- and post-participation survey study

Olivia A. C. Lamers, Meta Roestenberg, Martine C. de Vries, Marie-Astrid Hoogerwerf • Trials (2024)

Abstract Background Scientific advancement, including the testing and licensing of new drugs, relies heavily on clinical trials with healthy individuals. The motivations of clinical trial participants have been discussed intensively, as som...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13063-024-08582-z

DNA polymorphisms in inflammatory and endocrine signals linked to frailty are also associated with obesity: data from the FRASNET cohort

Sarah Damanti, Sarah Damanti, Lorena Citterio, Laura Zagato et al. • Frontiers in Endocrinology (2024)

BackgroundObesity and frailty are prevalent geriatric conditions that share some pathophysiological mechanisms and are associated with adverse clinical outcomes. The relationship between frailty, obesity, and polymorphism remains inadequate...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2024.1412160

Robotic Arthroplasty Clinical and cost Effectiveness Randomised controlled trial (RACER-knee): a study protocol

Martin Underwood, Charles E Hutchinson, Helen Parsons, James Mason et al. • BMJ Open (2023)

Introduction Robotic-assisted knee replacement systems have been introduced to healthcare services worldwide in an effort to improve clinical outcomes for people, although high-quality evidence that they are clinically, or cost-effective re...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2022-068255

Fritz-do-meu-coração:

Tristan Torriani • Kalagatos (2021)

Neste artigo apresento traduções inéditas em português de várias cartas de e a Friedrich Nietzsche durante década de 1880, visando esclarecer alguns aspectos da relação entre o filósofo e sua irmã Elisabeth. Embora o episódio envolvendo Lou...

DOAJ Open Access (DOAJ) DOI: 10.23845/kalagatos.v3i6.5759

Yoga Outcomes Get Assessed in Cystic Fibrosis (YOGA-CF): protocol of a multicentre interventional randomised controlled clinical trial—investigating effects of a 12-week yoga intervention for adults with cystic fibrosis

Adam P Wagner, Nicholas J Simmonds, Susan C Charman, P Scarborough et al. • BMJ Open Respiratory Research (2026)

Introduction Yoga is an emerging exercise choice for people with cystic fibrosis (CF), but evidence of its effect in this population is scarce, with a recent systematic review advocating for further research. Yoga Outcomes Get Assessed in C...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjresp-2025-003405

Effect of falls prevention interventions on falls and the risk factors for falls among cancer survivors: protocol for a systematic review

Lynette Mackenzie, Amanda M. Clifford, Eleanor Fallon, Joanna M. Allardyce • BMJ Open (2026)

Introduction Falls are a significant health concern and associated with cancer survivorship. Falls can result in negative psychosocial consequences for cancer survivors and economic sequelae for healthcare delivery. There are cancer-specifi...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2025-110212