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PRIMUS: Comprehensive proteomics of mouse intervertebral discs that inform novel biology and relevance to human disease modelling

Mateusz Kudelko, Peikai Chen, Vivian Tam, Ying Zhang et al. • Matrix Biology Plus (2021)

Mice are commonly used to study intervertebral disc (IVD) biology and related diseases such as IVD degeneration. Discs from both the lumbar and tail regions are used. However, little is known about compartmental characteristics in the diffe...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.mbplus.2021.100082

Piezo1 knockdown activates PI3K/AKT and enhances SPP1 to drive M2 macrophage polarization and reduce cardiac inflammation

Yunhan Zhang, Ying Zhang, Jiaoyan Song, Ziwen Zhao et al. • Scientific Reports (2026)

Abstract Piezo1 plays a key role in the immune response during sepsis. To date, our understanding of the role of Piezo1 in inflammatory diseases has mostly been limited to influencing vasomotor function and regulating inflammatory infiltrat...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-34794-7

Dietary effects of protein and lipid levels on growth performance and flesh quality of large-size largemouth bass (Micropterus salmoides)

Yunfeng Chen, Hang Yang, Beibei Guo, Xiaoqin Li et al. • Aquaculture Reports (2023)

The aim of this trial was to investigate the effects of dietary protein and lipid levels on growth performance and flesh quality of largemouth bass (Micropterus salmoides). A 3 × 3 two-factor design was used, including three crude protein l...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aqrep.2023.101852

Development of Rice Variety With Durable and Broad-Spectrum Resistance to Blast Disease Through Marker-Assisted Introduction of Pigm Gene

Zhiming Feng, Zhiming Feng, Mingyou Li, Zhiwen Xu et al. • Frontiers in Plant Science (2022)

Rice blast, caused by Magnaporthe oryzae (M. oryzae), is one of the most destructive diseases threatening rice production worldwide. Development of resistant cultivars using broad-spectrum resistance (R) genes with high breeding value is th...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpls.2022.937767

Causal analysis between altered levels of interleukins and obstructive sleep apnea

Minhan Yi, Minhan Yi, Minhan Yi, Wangcheng Zhao et al. • Frontiers in Immunology (2022)

BackgroundInflammation proteins including interleukins (ILs) have been reported to be related to obstructive sleep apnea (OSA). The aims of this study were to estimate the levels for several key interleukins in OSA and the causal effects be...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2022.888644

Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target

Xiaofeng Duan, Stephen Iwanowycz, Soo Ngoi, Megan Hill et al. • Frontiers in Oncology (2021)

During tumor development and progression, intrinsic and extrinsic factors trigger endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the increased expression of molecular chaperones to cope with the stress and...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2021.629846

Recuperação Completa de Doente com Carcinoma da Próstata Estádio IV Durante a Pandemia COVID-19

Gil Falcão, Cabrita Carneiro, Luís Campos Pinheiro • Gazeta Médica (2020)

A doença causada pelo coronavírus (COVID-19), inicialmente descrita em Wuhan, China, foi recentemente declarada pela Organização Mundial da Saúde (OMS) como uma pandemia global. A idade avançada e a presença de comorbilidades, característic...

DOAJ Open Access (DOAJ) DOI: 10.29315/gm.v7i2.328

Microenvironment‐adaptive nanodecoy synergizes bacterial eradication, inflammation alleviation, and immunomodulation in promoting biofilm‐associated diabetic chronic wound healing cascade

Lei Chen, Mengna Peng, Wei He, Xiaoli Hu et al. • Aggregate (2024)

Abstract The presence of bacterial biofilms and the occurrence of excessive inflammatory response greatly imped the healing process of chronic wounds in diabetic patients. However, effective strategies to simultaneously address these issues...

DOAJ Open Access (DOAJ) DOI: 10.1002/agt2.640

Small Object Detection Algorithm Based on Improved YOLOv8 for Remote Sensing

Hao Yi, Bo Liu, Bin Zhao, Enhai Liu • IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing (2024)

Due to the limitations of small targets in remote sensing images, such as background noise, poor information, and so on, the results of commonly used detection algorithms in small target detection is not satisfactory. To improve the accurac...

DOAJ Open Access (DOAJ) DOI: 10.1109/JSTARS.2023.3339235

An Interference Sensing Algorithm Based on Duration Units of Frequency Points for Adaptive Frequency-Hopping System

Duo Wang, Ju Wang, Yi Zhong • IEEE Access (2023)

The adaptive Frequency-Hopping(FH) technique based on interference sensing can further enhance the anti-interference performance of hybrid Direct-Sequence/FH Spread Spectrum(DS/FH SS) system and FH Orthogonal Frequency Division Multiplexing...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2023.3325252

Research on Personalized Recommendation Algorithm Integrating Cross-Grained Sentiment and Rating Interaction Features

Bing Li, Jiangtao Dong, Xile Wang, Yuqi Hou et al. • IEEE Access (2025)

To investigate the impact of cross-grained sentiments on user feature representation and address the issue of data sparsity, this paper proposes a Personalized Recommendation Algorithm Integrating Cross-Grained Sentiment and Rating Interact...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2025.3530431

Active Disturbance Rejection for Linear Induction Motors: A High-Order Sliding-Mode-Observer-Based Twisting Controller

Yongwen Liu, Lei Zhang, Pu Li, Yaoli Xu • Actuators (2025)

This paper presents a twisting controller (TC) based on a high-order sliding mode observer (HOSMO) for linear induction motors (LIMs), accounting for dynamic end effects. Based on the LIM model in the field-oriented frame, two extended subs...

DOAJ Open Access (DOAJ) DOI: 10.3390/act14040200

A Novel Depression Rehabilitation Game Framework Using VR Based on Neurofeedback

CAI Hanshu,WANG Ziyang,ZHANG Yanhao,CHEN Yunfei,HU Bi • Jisuanji gongcheng (2018)

At present,depression is treated with antidepressant drugs and assisted with psychotherapy and physical therapy,and these expensive and time-consuming treatment methods often end prematurely and result in a prolonged course without effectiv...

DOAJ Open Access (DOAJ) DOI: 10.19678/j.issn.1000-3428.0050904