Home »
Academic Articles & Research Papers
Showing 20 of 284 academic articles
Man Luo, Man Luo, Man Luo, Jiang Zhu et al. • Frontiers in Pharmacology
(2025)
BackgroundDrug repurposing has emerged as a promising approach for discovering novel anticancer therapeutics. In this study, we systematically investigated the antitumor potential of fedratinib, a JAK2 inhibitor approved for myelofibrosis, ...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fphar.2025.1689663
Chungsan Lim, Kirok Kwon, Kwangho Lee • Journal of Pharmacopuncture
(2014)
Objectives: The purpose of this study is to report a case of a plexiform neurofibroma (PNF) in the pelvic region treated with sweet bee venom (SBV) and mountain ginseng pharmacopuncture (MGP).
Methods: A 16-year-old girl was diagnosed as h...
DOAJ
Open Access (DOAJ)
DOI: 10.3831/KPI.2014.17.030
Hee-Sung Chae, Sun Young Kim, Pisey Pel, Jungmoo Huh et al. • Molecules
(2020)
Cough and phlegm frequently occur in respiratory diseases like upper respiratory tract infections, acute bronchitis, and chronic obstructive pulmonary diseases. To relieve these symptoms and diseases, various ingredients are being used desp...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules25133064
Lei Li, Anton A. Shemetov, Mikhail Baloban, Peng Hu et al. • Nature Communications
(2018)
Bacterial phytochrome-based probes improved sensitivity in photoacoustic computed tomography. Here the authors engineer a small near-infrared switchable photochromic probe that allows multi-contrast imaging at depths and can be adapted to s...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41467-018-05231-3
Xiaoyue Zhang, Yongkang Qiu, Jixin Zhang, Zhao Chen et al. • Frontiers in Medicine
(2024)
BackgroundLow-grade fibromyxoid sarcoma (LGFMS) is a rare type of soft tissue sarcoma that often involves the deep soft tissue of the extremities and trunk in young and middle-aged adults. It is uncommon in the elderly. Here we discuss a ca...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmed.2024.1172746
MIAO Xueyi, DING Lingyu, LU Jinling, ZHU Hanfei et al. • Huli yanjiu
(2022)
This article reviewed the research status quo and existing problems of mobile health（mHealth） in gastrointestinal tumor to provide a reference for the wide application of mHealth in the field of digestive tract tumors....
DOAJ
Open Access (DOAJ)
Yang Fei, Hui Xu, Chunwei Zhang, Jingjing Wang et al. • Beilstein Journal of Nanotechnology
(2025)
Esophageal cancer (EC) is a common malignant tumor of the digestive tract with poor prognosis and high mortality. The early diagnosis of EC mainly depends on endoscopic diagnosis, which not only needs to bear certain economic pressure, but ...
DOAJ
Open Access (DOAJ)
DOI: 10.3762/bjnano.16.121
Fatma H. El-Didi, Marwa M. Essawy, Sagy L. Asar, Sahar M. El-Sheikh et al. • Alexandria Dental Journal
(2019)
INTRODUCTION: Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide with high mortality rate. Conventional treatment strategies have improved but remain far from optimal. Cancer research is focused on improving cance...
DOAJ
Open Access (DOAJ)
DOI: 10.21608/adjalexu.2019.57569
Yawei Sun, Shuai Wang, Xingwei Zhang, Zhuhao Wu et al. • Biomolecules
(2021)
Background: Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a key enzyme that catalyzes the hydroxylation of lysine, plays a crucial role in the progression of several solid tumors. However, its spatial expression profile and pr...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/biom11121842
Claudio Tomi-Andrino, Alina Pandele, Klaus Winzer, John King et al. • Scientific Reports
(2022)
Abstract The manifestation of intra- and inter-tumor heterogeneity hinders the development of ubiquitous cancer treatments, thus requiring a tailored therapy for each cancer type. Specifically, the reprogramming of cellular metabolism has b...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41598-022-14721-w
Heabin Kim, Hyun-Taek Kim, Seung-Hyun Jung, Jong Won Han et al. • Marine Drugs
(2023)
The discovery of new highly effective anticancer drugs with few side effects is a challenge for drug development research. Natural or synthetic anticancer peptides (ACPs) represent a new generation of anticancer agents with high selectivity...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/md21120607
Xuanzhao Chen, Zeyan Li, Meihua Liang, Ziyang Zhang et al. • World Journal of Surgical Oncology
(2023)
Abstract Background Triple-negative breast cancer (TNBC) is the most heterogenous and aggressive subtype of breast cancer. Chemotherapy remains the standard treatment option for patients with TNBC owing to the unavailability of acceptable t...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12957-023-03078-7
Hai-Ning Wee, Soek-Ying Neo, Deepika Singh, Hui-Chuing Yew et al. • BMC Complementary Medicine and Therapies
(2020)
Abstract Background Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growing in co...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12906-020-02884-w
Youfeng Shen, Kaixiang Xu, Zaimei Yuan, Jianxiong Guo et al. • Journal of Translational Medicine
(2017)
Abstract Background Pigs have many features that make them attractive as biomedical models for various diseases, including cancer. P53 is an important tumor suppressor gene that exerts a central role in protecting cells from oncogenic trans...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12967-017-1327-0
Tara Alaadin Abdulrazzaq, Jangi Shawakat Salayi • Advanced Medical Journal
(2023)
Background & Objectives: Colorectal cancer is the commonest malignancy in the gastrointestinal tract third and the second leading cause of cancer death worldwide. The advanced stages and poor tumor grade of colorectal cancer are likely to b...
DOAJ
Open Access (DOAJ)
DOI: 10.56056/amj.2023.202
Valerio Nardone, Federica Marmorino, Marco Maria Germani, Natalia Cichowska-Cwalińska et al. • Current Oncology
(2024)
The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in per...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/curroncol31090369
Wenjie Wu, Rongjing Xia, Si Ma, Zenglei Hu et al. • Poultry Science
(2026)
Newcastle disease (ND) caused by Newcastle disease virus (NDV) infection is a highly contagious avian disease that causes substantial threat to the global poultry industry. Emodin (EMO), a member of the free anthraquinone compounds derived ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.psj.2026.107180
PMC: PMC13265661
John P Zepecki, David Karambizi, J Eduardo Fajardo, Kristin M Snyder et al. • PLoS Genetics
(2021)
Within the glioblastoma cellular niche, glioma stem cells (GSCs) can give rise to differentiated glioma cells (DGCs) and, when necessary, DGCs can reciprocally give rise to GSCs to maintain the cellular equilibrium necessary for optimal tum...
DOAJ
Open Access (DOAJ)
DOI: 10.1371/journal.pgen.1009086
Auriemma Lauren B, Shah Shaili, Linden Lara M, Henriksen Melissa A • Epigenetics & Chromatin
(2012)
Abstract Background The tumor suppressor menin (MEN1) is mutated in the inherited disease multiple endocrine neoplasia type I, and has several documented cellular roles, including the activation and repression of transcription effected by s...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/1756-8935-5-2
Chunfu Wang, Songmao Liang, Jiachen Xu, Yingfan Zhai et al. • Separations
(2024)
Futibatinib is an excellent fibroblast growth factor receptor 1–4 (FGFR 1–4) inhibitor that exhibits selective anti-tumor activeness against FGFR-deregulated tumors. A new high-performance liquid chromatography-tandem mass spectrometry (HPL...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/separations11070213