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miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology (2021)

Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-021-01127-x

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24

ChsA, a Class Ⅱ Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids in <i>Aspergillus niger</i>

Yunqi Zhu, Tong Liu, Yingsi Wang, Guojun Chen et al. • Journal of Fungi (2023)

Chitin synthases (CHSs) are vital enzymes for the synthesis of chitin and play important and differential roles in fungal development, cell wall integrity, environmental adaptation, virulence, and metabolism in fungi. However, except for Ch...

DOAJ Open Access (DOAJ) DOI: 10.3390/jof9080801

Natural Polyphenols for the Preservation of Meat and Dairy Products

Hammad Ullah, Yaseen Hussain, Cristina Santarcangelo, Alessandra Baldi et al. • Molecules (2022)

Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, sa...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27061906

The Challenge of Timely, Responsive and Rigorous Ethics Review of Disaster Research: Views of Research Ethics Committee Members.

Matthew Hunt, Catherine M Tansey, James Anderson, Renaud F Boulanger et al. • PLoS ONE (2016)

Research conducted following natural disasters such as earthquakes, floods or hurricanes is crucial for improving relief interventions. Such research, however, poses ethical, methodological and logistical challenges for researchers. Oversig...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0157142

Let's Play it Safe: Ethical Considerations from Participants in a Photovoice Research Project

Karin Hannes PhD, Oksana Parylo PhD • International Journal of Qualitative Methods (2014)

The use of images and other visual data in qualitative research projects poses new ethical challenges, particularly in the context of participatory research projects that engage research participants in conducting fieldwork. Little is known...

DOAJ Open Access (DOAJ) DOI: 10.1177/160940691401300112

Perceived community environment and depressive symptoms among older adults in China: a cross-sectional analysis of physical activity as a moderator

Zhijia Du, Junyue Yue, Zirui Lin, Xiaoyu Han • Frontiers in Psychology (2026)

IntroductionPerceived community environment is an important contextual factor related to depressive symptoms in later life. However, few studies have examined whether physical activity (PA), a modifiable behavioral factor, moderates this as...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyg.2026.1893833

Analysis of Long-Term Impact of Maintenance Policy on Maintenance Capacity Using a Time-Driven Activity-Based Life-Cycle Costing

Orlando Durán, Paulo Afonso, Vinicius Minatogawa • Mathematics (2020)

In capital-intensive industries, physical assets and maintenance activities play a relevant and strategic role in terms of providing operational continuity and business sustainability. As a result, maintenance support structures are highly ...

DOAJ Open Access (DOAJ) DOI: 10.3390/math8122208

Internal Decoupling in Nonlinear Process Control

Jens G. Balchen, Bernt Lie, Ingar Solberg • Modeling, Identification and Control (1988)

A simple method has been investigated for the total or partial removal of the effect of non-linear process phenomena in multi-variable feedback control systems. The method is based upon computing the control variables which will drive the p...

DOAJ Open Access (DOAJ) DOI: 10.4173/mic.1988.3.3

A Fractional-Order Complexity Framework for Misinformation Propagation With Fact-Checking Saturation and Social Vulnerability Dynamics

Shewafera Wondimagegnhu Teklu, M. A. Abdelkawy, Waleed Adel • Complexity (2026)

Misinformation spreads through communities in ways that resemble infectious diseases, but existing mathematical models often miss three real-world complexities: People remember past information (memory effects), some folks are more easily f...

DOAJ Open Access (DOAJ) DOI: 10.1155/cplx/8861194

Mathematical modeling of the COVID-19 pandemic with intervention strategies

Subhas Khajanchi, Kankan Sarkar, Jayanta Mondal, Kottakkaran Sooppy Nisar et al. • Results in Physics (2021)

Mathematical modeling plays an important role to better understand the disease dynamics and designing strategies to manage quickly spreading infectious diseases in lack of an effective vaccine or specific antivirals. During this period, for...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rinp.2021.104285

Global quantum correlations in finite-size spin chains

S Campbell, L Mazzola, G De Chiara, T J G Apollaro et al. • New Journal of Physics (2013)

We perform an extensive study of the properties of global quantum correlations in finite-size one-dimensional quantum spin models at finite temperature. By adopting a recently proposed measure for global quantum correlations (Rulli and Sara...

DOAJ Open Access (DOAJ) DOI: 10.1088/1367-2630/15/4/043033

Feasibility study for interactive reporting of network meta-analysis: experiences from the development of the MetaInsight COVID-19 app for stakeholder exploration, re-analysis and sensitivity analysis from living systematic reviews

Yiqiao Xin, Clareece R. Nevill, Janion Nevill, Ewan Gray et al. • BMC Medical Research Methodology (2022)

Abstract Background Network meta-analysis (NMA) has been increasingly adopted worldwide by Cochrane reviews, guideline developers and decision-making bodies to identify optimal treatment choices. However, NMA results are often produced stat...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12874-022-01507-x

Development and validation of a portable, point-of-care canine distemper virus qPCR test.

Ania Tomaszewicz Brown, Denise McAloose, Paul P Calle, Angelika Auer et al. • PLoS ONE (2020)

Canine distemper virus (CDV) is a multi-host pathogen that can cause significant mortality in domestic, wild terrestrial and marine mammals. It is a major conservation threat in some endangered species. Infection can result in severe respir...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0232044

Development of WEFIT Screening Tool for Assessing Pre-exercise Fitness Level for Older Adults in Peninsular Malaysia

Divya Vanoh, Arimi Fitri Mat Ludin, Suzana Shahar, Shahrul Azman Mohd Noah et al. • Journal of Health Research (2022)

Background: Pre-exercise screening is important to identify the fitness level of older adults prior to performing exercise. This study aimed to develop a screening tool for identifying older adults with poor physical fitness prior to exerci...

DOAJ Open Access (DOAJ) DOI: 10.56808/2586-940x.1006

Treatment seeking behaviors related to gonorrhea among female sex workers in 7 cities in Indonesia

Roselinda Roselinda, Nelly Puspandari • Health Science Journal of Indonesia (2014)

Abstrak Latar belakang:Gonore merupakan salah satu infeksi menular seksual yang menjadi permasalahan besar kesehatan terutama pada wanita penjaja seks (WPS) di Indonesia. Tujuan dari artikel ini adalah untuk melihat hubungan antara pola pen...

DOAJ Open Access (DOAJ) DOI: 10.22435/hsji.v4i2 Des.3438.87-92

Evaluation of Blood-Based Antibody Rapid Testing for HIV Early Therapy: A Meta-Analysis of the Evidence

Xiaojie Huang, Xinchao Liu, Jieqing Chen, Yugang Bao et al. • Frontiers in Immunology (2018)

BackgroundWestern blot (WB) assay is considered the gold standard test for HIV infection confirmation. However, it requires technical expertise and is quite time-consuming. WHO recommends blood-based rapid diagnosis to achieve same-day test...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2018.01458

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Vladimir Tesar, Conor Judge, John Kelleher, Zdenka Hrušková et al. • RMD Open (2024)

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS&gt;0) is often missing or inaccurate in re...

DOAJ Open Access (DOAJ) DOI: 10.1136/rmdopen-2023-003962

Innovative polymer-based electrochemical platform for detecting ESAT-6 in human blood for pulmonary tuberculosis diagnosis

Xiu-An Ye, Shu-Hong Lin, Liang-Yu Chen, Jie-Ren Li et al. • Sensing and Bio-Sensing Research (2025)

Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), necessitates early diagnosis for effective patient care. Despite advancements in TB diagnostics, there remains an urgent need to discover innovative non-sputum-based m...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.sbsr.2025.100816