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Admission prognostic nutritional index improves risk stratification for the carbapenem-resistant phenotype in culture-positive Klebsiella pneumoniae: a retrospective cohort study

Kaixuan Zhang, Huihui Li, Yuanyuan Xu, Sudi Zhu et al. • Frontiers in Cellular and Infection Microbiology (2026)

BackgroundCarbapenem-resistant Klebsiella pneumoniae (CRKP) remains an infection-control challenge. We assessed whether admission immuno-nutritional status, measured by the Prognostic Nutritional Index (PNI), is associated with the CRKP phe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2026.1828441

Why do emergency department clinicians miss acute aortic syndrome? A case series and descriptive analysis

Rachel McLatchie, Sarah Wilson, Matthew Reed, Francoise Ticehurst et al. • Emergency Care Journal (2023)

Objectives: To understand why the diagnosis of AAS is missed in the ED, and to characterise the presenting features of cases in which a diagnosis of AAS was missed. Methods: A retrospective case series cohort study was performed, identif...

DOAJ Open Access (DOAJ) DOI: 10.4081/ecj.2023.11153

Longevity of dental restorations in Sjogren’s disease patients using electronic dental and health record data

Grace Gomez Felix Gomez, Mei Wang, Zasim A. Siddiqui, Theresa Gonzalez et al. • BMC Oral Health (2024)

Abstract Background Decreased salivary secretion is not only a risk factor for carious lesions in Sjögren’s disease (SD) but also an indicator of deterioration of teeth with every restorative replacement. This study determined the longevity...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12903-024-03957-9

Association of triglyceride glucose-body roundness index and body roundness index with incident sarcopenia among Chinese older adults: A nationwide cohort study

Yu -Yang Ma, Hai-Yan Li, Ruo-Nan Yao, Gong Cheng et al. • Experimental Gerontology (2025)

Background: The relationship between TyG-BRI, BRI, and the sarcopenia definition proposed by the Asian Working Group for Sarcopenia (AWGS) in 2019 remains unclear. This research focused on exploring the relationship between the TyG-BRI inde...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.112946

Hospitalisations for physical abuse in infants and children less than 5 years, 2013‒2021: a multinational cohort study using administrative data from five European countries

Catherine Quantin, Jonathan Cottenet, Colleen Chambers, Natasha Kennedy et al. • International Journal of Population Data Science (2025)

Objectives Child physical abuse (CPA) is a global public health problem associated with lifelong negative consequences, yet reliable epidemiologic data are lacking. We did a multinational cohort study to analyse trends in CPA hospitalisatio...

DOAJ Open Access (DOAJ) DOI: 10.23889/ijpds.v10i3.3028

TRACK-CF prospective cohort study: Understanding early cystic fibrosis lung disease

Eva Steinke, Eva Steinke, Eva Steinke, Olaf Sommerburg et al. • Frontiers in Medicine (2023)

BackgroundLung disease as major cause for morbidity in patients with cystic fibrosis (CF) starts early in life. Its large phenotypic heterogeneity is partially explained by the genotype but other contributing factors are not well delineated...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.1034290

Psychological STress, Anxiety, and Depression After miscarriage in comparison to successful pregnancy and abortion: design and protocol for the observational cohort study STRADA

Maarit Mentula, Oskari Heikinheimo, Katri Räikkönen, Heini Sorasto et al. • BMJ Open (2026)

Introduction Miscarriage occurs in 15%–20% of clinically recognised pregnancies. It may cause acute or prolonged psychological distress such as anxiety, depression and post-traumatic stress disorder (PTSD). Data on symptom severity and dura...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2026-127865

Changes in the comprehensive unassisted pregnancy rate as a possible marker of declining human fecundity

Rune Lindahl-Jacobsen, Astrid Linnea Beck, Lærke Priskorn, Stine Agergaard Holmboe et al. • Scientific Reports (2025)

Abstract Recent decades have seen declining total fertility rates (TFR) globally, alongside increased use of assisted reproductive technology (ART). However, TFR includes ART births and excludes induced abortions, complicating assessments o...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-08332-4

Parental Birth-Related PTSD Symptoms and Bonding in the Early Postpartum Period: A Prospective Population-Based Cohort Study

Suzannah Stuijfzand, Susan Garthus-Niegel, Susan Garthus-Niegel, Susan Garthus-Niegel et al. • Frontiers in Psychiatry (2020)

The parent-infant bond following childbirth is an important facilitator of optimal infant development. So far, research has mainly focused on mother-infant bonding. Data on fathers are still sparse. Parental mental health, such as posttraum...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2020.570727

Musculoskeletal pain is not clearly associated with the risk of anterior cruciate ligament reconstruction in adolescents

John-Anker Zwart, Kjersti Storheim, Anne Marie Fenstad, Maren Hjelle Guddal et al. • BMJ Open Sport & Exercise Medicine (2023)

Objectives The purpose of this study was to investigate whether self-reported musculoskeletal pain (MSP) was associated with a future anterior cruciate ligament reconstruction (ACLR).Methods In this population-based prospective cohort study...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjsem-2022-001453

Preoperative and intraoperative assessment of myometrial invasion in patients with FIGO stage I non-endometrioid endometrial carcinoma—a large-scale, multi-center, and retrospective study

Xiaohang Yang, Jingjing Yin, Yu Fu, Yuanming Shen et al. • Diagnostic Pathology (2023)

Abstract Introduction Myometrial invasion is a prognostic factor for lymph node metastases and decreased survival in non-endometrioid endometrial carcinoma patients. Herein, we explored the mode of myometrial invasion diagnosis in FIGO stag...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-023-01294-z

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Vladimir Tesar, Conor Judge, John Kelleher, Zdenka Hrušková et al. • RMD Open (2024)

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS>0) is often missing or inaccurate in re...

DOAJ Open Access (DOAJ) DOI: 10.1136/rmdopen-2023-003962

The Comparability of Men Who Have Sex With Men Recruited From Venue-Time-Space Sampling and Facebook: A Cohort Study

Hernandez-Romieu, Alfonso C, Sullivan, Patrick S, Sanchez, Travis H, Kelley, Colleen F et al. • JMIR Research Protocols (2014)

BackgroundRecruiting valid samples of men who have sex with men (MSM) is a key component of the US human immunodeficiency virus (HIV) surveillance and of research studies seeking to improve HIV prevention for MSM. Social media, such as Face...

DOAJ Open Access (DOAJ) DOI: 10.2196/resprot.3342

Remote Patient Monitoring System for Polypathological Older Adults at High Risk for Hospitalization: Retrospective Cohort Study

Damien Testa, Israa Salma, Vincent Iborra, Victoire Roussel et al. • Journal of Medical Internet Research (2025)

Abstract BackgroundHealth care systems are increasingly facing challenges posed by the aging of populations. In particular, hospitalization, both initial and subsequent, is often observed among older adult patients. However, res...

DOAJ Open Access (DOAJ) DOI: 10.2196/71527

A genome-wide association study on meat consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort study

Yasuyuki Nakamura, Akira Narita, Yoichi Sutoh, Nahomi Imaeda et al. • Journal of Nutritional Science (2021)

Recent genome-wide association studies (GWAS) on the dietary habits of the Japanese population have shown that an effect rs671 allele was inversely associated with fish consumption, whereas it was directly associated with coffee consumption...

DOAJ Open Access (DOAJ) DOI: 10.1017/jns.2021.49

Missed Healthcare Visits During the COVID-19 Pandemic: A Longitudinal Study

Jethel Hernandez, Stephanie Batio, Rebecca Mullen Lovett, Michael S. Wolf et al. • Journal of Primary Care & Community Health (2024)

Introduction: Missed visits have been estimated to cost the U.S. healthcare system $50 billion annually and have been linked to healthcare inefficiency, higher rates of emergency department visits, and worse outcomes. COVID-19 disrupted exi...

DOAJ Open Access (DOAJ) DOI: 10.1177/21501319241233869

The influence of patient characteristics on the alarm rate in intensive care units: a retrospective cohort study

Zeena-Carola Sinno, Denys Shay, Jochen Kruppa, Sophie A.I. Klopfenstein et al. • Scientific Reports (2022)

Abstract Intensive care units (ICU) are often overflooded with alarms from monitoring devices which constitutes a hazard to both staff and patients. To date, the suggested solutions to excessive monitoring alarms have remained on a research...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-26261-4

Association of maternal metabolic risk factors with offspring body mass index (BMI) trajectories in early childhood: a retrospective cohort study

Wei Song, Xiao Yang, Liu Yang, Yan Ren et al. • BMJ Open (2025)

Objective This study aimed to identify body mass index (BMI) growth trajectories from birth to 24 months of age and examine the independent and additive effects of four maternal metabolic risk factors, namely prepregnancy BMI, the rate of g...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2024-088641

Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol

MinJae Lee, Anna M Georgiopoulos, Raksha Jain, Traci M Kazmerski et al. • BMJ Open Respiratory Research (2024)

Introduction People with cystic fibrosis (CF) are living longer and healthier lives with a growing number considering and pursuing parenthood. The decision of whether to become a parent is complex for people with CF, and CF is a major facto...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjresp-2024-002383

Mortality trends among hospitalised COVID-19 patients in Sweden: A nationwide observational cohort study

Kristoffer Strålin, Erik Wahlström, Sten Walther, Anna M Bennet-Bark et al. • The Lancet Regional Health. Europe (2021)

Background: It is important to know if mortality among hospitalised COVID-19 patients has changed as the pandemic has progressed. The aim of this study was to describe the dynamics over time of mortality among patients hospitalised for COVI...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.lanepe.2021.100054