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Evaluating stool microbiome integrity after domestic freezer storage using whole-metagenome sequencing, genome assembly, and antimicrobial resistance gene analysis

Paula Momo Cabrera, Nicholas A. Bokulich, Petra Zimmermann • Microbiology Spectrum (2025)

ABSTRACT The gut microbiome is crucial for host health. Early childhood is a critical period for the development of a healthy gut microbiome, but it is particularly sensitive to external influences. Recent research has focused on using adva...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.02278-24

Antimicrobial compound from Trichoderma harzianum, an endophytic fungus associated with ginger (Zingiber officinale)

Harwoko Harwoko, Jungho Lee, Georgios Daletos, Michael Feldbrügge et al. • JKKI (Jurnal Kedokteran dan Kesehatan Indonesia) (2021)

Background: Genus Trichoderma of fungal kingdom are largely used as biological control agents due to broad-spectrum activity against plant pathogens. Objective: This study aimed to investigate Trichoderma harzianum, an endophytic fungus obt...

DOAJ Open Access (DOAJ) DOI: 10.20885/JKKI.Vol12.Iss2.art8

Purification, Characterization and Bactericidal Action of Lysozyme, Isolated from <i>Bacillus subtillis</i> BSN314: A Disintegrating Effect of Lysozyme on Gram-Positive and Gram-Negative Bacteria

Muhammad Naveed, Yadong Wang, Xian Yin, Malik Wajid Hussain Chan et al. • Molecules (2023)

In the present study, lysozyme was purified by the following multi-step methodology: salt (ammonium sulfate) precipitation, dialysis, and ultrafiltration. The lysozyme potential was measured by enzymatic activity after each purification ste...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28031058

Key Variables for Effective eHealth Designs for Individuals With and Without Mental Health Disorders: 2^12-4 Fractional Factorial Experiment

Rotondi, Armando J, Grady, Jonathan, Hanusa, Barbara H, Haas, Gretchen L et al. • Journal of Medical Internet Research (2021)

BackgroundeHealth applications not only offer the potential to increase service convenience and responsiveness but also expand the ability to tailor services to improve relevance, engagement, and use. To achieve these goals, it is critical ...

DOAJ Open Access (DOAJ) DOI: 10.2196/23137

Recommendations of the German Association for Medical Informatics, Biometry and Epidemiology for Education and Training in Medical Informatics

J. Dudeck, Wilhelm Gaus, Franz Josef Leven, Hildebrand Kunath et al. • Methods of Information in Medicine (1992)

In the fields of health care and medicine there is an immense demand for a systematic application of methods of information processing and for the use of computers. Obviously, to that end well-trained scientists and qualified personnel must...

OPENALEX DOI: https://doi.org/10.1055/s-0038-1634857

Solar spectra datasets at optimum and vertical installation angles in central Europe (Berlin) during 2020, 2021 and 2022

Guillermo A. Farias-Basulto, Maximilian Riedel, Mark Khenkin, Rutger Schlatmann et al. • Data in Brief (2023)

This article provides datasets containing three years worth of solar spectra for the optimum installation angle of 35° and the building-integrated-photovoltaics relevant vertical angle of 90°. These datasets were obtained by measuring the s...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2023.109273

Case-based medical informatics

Stefan Valerian Pantazi, José F. Arocha, Jochen R. Moehr • BMC Medical Informatics and Decision Making (2004)

BACKGROUND: The "applied" nature distinguishes applied sciences from theoretical sciences. To emphasize this distinction, we begin with a general, meta-level overview of the scientific endeavor. We introduce the knowledge spectrum and four ...

OPENALEX cc-by DOI: https://doi.org/10.1186/1472-6947-4-19 PMC: 544898

Can Oscillometry Replace Spirometry as a Major Tool for Lung Function Testing? – An Overview

Jaymohan Unnithan, Srikanth Krishnamurthy, Nandagopal Velayuthaswamy, Nagarajan Srinivasan • Journal of Association of Pulmonologist of Tamil Nadu (2024)

Developing countries face a huge challenge in managing obstructive lung disorders due to frequency, severity, management, and economic impact. Spirometry has been the popular choice to assess the severity and reversibility of airflow obstru...

DOAJ Open Access (DOAJ) DOI: 10.4103/japt.japt_1_24

Correlation of Social Network Attributes with Individuals’ Score on Bipolar Spectrum Diagnostic Scale

Amir Momeni Boroujeni, Nima Khalighinejad, Elham Yousefi, Elham Asadi • Basic and Clinical Neuroscience (2012)

Introduction: Bipolar Spectrum Disorders include a variety of mood disorders from bipolar II disorder to conditions characterized by hyperthymic mood states. It has been suggested that psychosocial factors also play an important role in bip...

DOAJ Open Access (DOAJ)

Fipronil disturbs the antigen-specific immune responses and GABAergic gene expression in the ovalbumin-immunized BALB/c mice

Jui-Fang Kuo, Yin-Hua Cheng, Chun-Wei Tung, Chia-Chi Wang • BMC Veterinary Research (2024)

Abstract Background Fipronil (FPN) is a broad-spectrum pesticide and commonly known as low toxicity to vertebrates. However, increasing evidence suggests that exposure to FPN might induce unexpected adverse effects in the liver, reproductiv...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12917-024-03878-3

In vitro inhibition of SARS-CoV-2 Infection by dry algae powders

Daniel Garcia-Ruiz, Erendira Villalobos-Sánchez, David Alam-Escamilla, Darwin Elizondo-Quiroga • Scientific Reports (2022)

Abstract Chlorella spp., Spirulina spp., and fucoidan dry powders, are commercialized as food supplements and are considered safe for human consumption. Their broad-spectrum antiviral properties have been studied, however, their effect agai...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-22148-6

High level non-carbapenemase carbapenem resistance by overlaying mutations of mexR, oprD, and ftsI in Pseudomonas aeruginosa

Yan Yang, Xue Li, Lang Sun, Xiu-Kun Wang et al. • Microbiology Spectrum (2025)

ABSTRACT Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global threat, but the mechanism of non-carbapenemase carbapenem resistance is still unclear. In the current study, we investigated the contributions of point mutations in mex...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.01398-24

Isolation, characterization, and genomic analysis of a novel phage WSPA with lytic activity against Serratia marcescens

Lijuan Li, Kunkun Li, Yu Mi, Xiumei Wu et al. • Microbiology Spectrum (2025)

ABSTRACT Serratia marcescens is an established pathogen implicated in hospital-acquired infections and is notorious for its propensity to form biofilms on medical devices, leading to persistent environmental contamination and increased infe...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.02716-24

Evidence for the Effectiveness of Remdesivir (GS-5734), a Nucleoside-Analog Antiviral Drug in the Inhibition of IK(M) or IK(DR) and in the Stimulation of IMEP

Wei-Ting Chang, Wei-Ting Chang, Wei-Ting Chang, Ping-Yen Liu et al. • Frontiers in Pharmacology (2020)

Remdesivir (RDV, GS-5734), a broad-spectrum antiviral drug in the class of nucleotide analogs, has been particularly tailored for treatment of coronavirus infections. However, to which extent RDV is able to modify various types of membrane ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2020.01091

Expanding the genetic spectrum of hereditary motor sensory neuropathies in Pakistan

Asif Naveed Ahmed, Lettie E. Rawlins, Niamat Khan, Zakir Jan et al. • BMC Neurology (2024)

Abstract Background Hereditary motor and sensory neuropathy (HMSN) refers to a group of inherited progressive peripheral neuropathies characterized by reduced nerve conduction velocity with chronic segmental demyelination and/or axonal dege...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12883-024-03882-y

Parents’ Perceptions of the Problems in Children With Autism Spectrum Disorders: A Qualitative Study

Masume Zareei, Seyed Abolfazl Tohidast, Masoomeh Salmani • Iranian Rehabilitation Journal (2022)

Objectives: Parents of children with autism spectrum disorder (ASD) have valuable experiences of the possible developmental problems and other issues of their children as the primary caregivers. The present study aimed to obtain proper info...

DOAJ Open Access (DOAJ)

International Relations Theories

• Oxford University Press eBooks (2020)

The fifth edition of this text provides coverage of international relations theories and arguments. The chapters explore the full spectrum of theoretical perspectives and debates, ranging from the historically dominant traditions of realism...

OPENALEX DOI: https://doi.org/10.1093/hepl/9780198814443.001.0001

The Oxford Handbook of International Relations

• Oxford University Press eBooks (2008)

Abstract The Oxford Handbook of International Relations offers the most authoritative and comprehensive overview to date of the field of international relations. Bringing together an impressive collection of international relations scholars...

OPENALEX DOI: https://doi.org/10.1093/oxfordhb/9780199219322.001.0001