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Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

Marie E Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, Rebecca Petri et al. • Nature Communications (2019)

DNA methylation plays an important role in silencing transposable elements. Here the authors find that loss of DNMT1 and DNA methylation leads to transcriptional activation and chromatin remodelling of evolutionarily young—hominoid-specific...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-019-11150-8

Necroptosis and Neuroinflammation in Retinal Degeneration

Yan Tao, Yusuke Murakami, Demetrios G. Vavvas, Koh-Hei Sonoda • Frontiers in Neuroscience (2022)

Necroptosis mediates the chronic inflammatory phenotype in neurodegeneration. Receptor-interacting protein kinase (RIPK) plays a pivotal role in the induction of necroptosis in various cell types, including microglia, and it is implicated i...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2022.911430

Prevalence of Constipation in Elderly and Its Association With Dementia and Mild Cognitive Impairment: A Cross-Sectional Study

Fei Wang, Fei Wang, Min Fei, Min Fei et al. • Frontiers in Neuroscience (2022)

BackgroundConstipation and dementia have similar epidemiological characteristics. Changes in intestinal flora and characteristics of the brain-gut axis play roles in the pathogeneses of the two diseases, suggesting that there may be a close...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2021.821654

Alterations in white matter fiber density associated with structural MRI and metabolic PET lesions following multimodal therapy in glioma patients

Michel Friedrich, Ezequiel Farrher, Svenja Caspers, Svenja Caspers et al. • Frontiers in Oncology (2022)

BackgroundIn glioma patients, multimodality therapy and recurrent tumor can lead to structural brain tissue damage characterized by pathologic findings in MR and PET imaging. However, little is known about the impact of different types of d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.998069

Hamartin: An Endogenous Neuroprotective Molecule Induced by Hypoxic Preconditioning

Sijie Li, Sijie Li, Changhong Ren, Changhong Ren et al. • Frontiers in Genetics (2020)

Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be involved. Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such mol...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2020.582368

Role of Coffee Caffeine and Chlorogenic Acids Adsorption to Polysaccharides with Impact on Brew Immunomodulation Effects

Cláudia P. Passos, Rita M. Costa, Sónia S. Ferreira, Guido R. Lopes et al. • Foods (2021)

Coffee brews have High Molecular Weight (HMW) compounds with described immunostimulatory activity, namely polysaccharides and melanoidins. Melanoidins are formed during roasting and are modified during brews technological processing. In add...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods10020378

Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation

Akihiro Sugai, Taisuke Kato, Akihide Koyama, Yuka Koike et al. • Neurobiology of Disease (2019)

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by accumulation of fragmented insoluble TDP-43 and loss of TDP-43 from the nucleus. Increased expression of exogenous TARDBP (encoding TDP-43) induces TDP-43 p...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nbd.2019.104534

The role of attachment insecurity in the emergence of anxiety symptoms in children and adolescents with migraine: an empirical study

Riccardo Williams, Luigi Leone, Noemi Faedda, Giulia Natalucci et al. • The Journal of Headache and Pain (2017)

Abstract Background It is widely recognised that there are associations between headache, psychiatric comorbidity and attachment insecurity in both adults and children. The aims of this study were: 1) to compare perceived attachment securit...

DOAJ Open Access (DOAJ) DOI: 10.1186/s10194-017-0769-3

Frontiers in Human Neuroscience

Alessio Avenanti • Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (2013)

Frontiers in Human Neuroscience is a first-tier electronic journal devoted to understanding the brain mechanisms supporting cognitive and social behavior in humans, and how these mechanisms might be altered in disease states. The last 25 ye...

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Neuroscience in Medicine

P. Michael Conn • Humana Press eBooks (2003)

Cytology and Organization of Cell Types: Light and Electron Microscopy Rochelle S. Cohen and Donald W. Pfaff Anatomy of the Spinal Cord and Brain Bruce E. Maley Ion Channels and Electrical Signaling Stanko S. Stojilkovic A. Clinical Correla...

OPENALEX DOI: https://doi.org/10.1007/978-1-59259-371-2

Computational Neuroscience

Terrence J. Sejnowski A B, Christof Koch, Patricia Smith Churchland • Science (1988)

The ultimate aim of computational neuroscience is to explain how electrical and chemical signals are used in the brain to represent and process information. This goal is not new, but much has changed in the last decade. More is known now ab...

OPENALEX DOI: https://doi.org/10.1126/science.3045969

Neuroscience and education

Usha Goswami • British Journal of Educational Psychology (2004)

Neuroscience is a relatively new discipline encompassing neurology, psychology and biology. It has made great strides in the last 100 years, during which many aspects of the physiology, biochemistry, pharmacology and structure of the verteb...

OPENALEX Open Access DOI: https://doi.org/10.1348/000709904322848798